John Jacob Abel

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John Jacob Abel

John Jacob Abel (born May 19, 1857 in Cleveland , Ohio , † May 26, 1938 in Baltimore , Maryland ) was an American physician, pharmacologist and biochemist .

life and work

Abel began studying at the University of Michigan at Ann Arbor in 1876 , but he had to interrupt it from 1879 to 1882 for financial reasons. He studied medicine, pharmacology, biochemistry and chemistry at Johns Hopkins University in Baltimore and with Carl Ludwig at the University of Leipzig . He also studied in Strasbourg , Würzburg , Heidelberg , Vienna , Berlin and Paris . In Strasbourg he was awarded a Dr. med. PhD. In 1891 he became Professor of Medicine and Therapeutics at the University of Michigan at Ann Arbor. When he was offered a professorship in pharmacology at Johns Hopkins University in 1893, he went to Schmiedeberg in Strasbourg and asked him for a recommendation for his successor. He recommended his own assistant, Arthur Robertson Cushny, as his successor. Cushny worked successfully at the University of Michigan at Ann Arbor from 1893 to 1905. Abel stayed at Johns Hopkins until his retirement in 1932.

Abel is considered one of the pioneers of early hormone research and became known for his studies of the adrenal hormone adrenaline . Along with Napoleon Cybulski and Jokichi Takamine, he was the first to isolate adrenaline in 1897; he called it "epinephrine". In 1926 he presented the hormone insulin in crystalline form. His search for the central pituitary hormone , however, was unsuccessful, and later it turned out that it was a large number of hormones.

John Jacob Abel is co-founder of scientific journals Journal of Biological Chemistry (1905) and Journal of Pharmacology and Experimental Therapeutics (1909). In 1912 Abel was elected to the National Academy of Sciences , in 1925 he was elected a member of the Leopoldina Academy of Scholars . In the same year he gave the first George M. Kober Lecture . In 1933 he became a member of the Royal Society of Edinburgh , in 1934 he received the Kober Medal .

Honoring the name of its founder, the American Society for Pharmacology and Experimental Therapeutics (ASPET) annually awards the John J. Abel Award in Pharmacology and Experimental Therapeutics for original and outstanding research by a pharmacologist under 42 years of age. The prize is awarded at $ 5,000.

Important writings

  • About the part of the adrenal gland that causes blood pressure, epinephrine. In: Zeitschrift für Physiologische Chemie , 28, 1899, pp. 318-362.
  • Some recent advances in our knowledge of the ductless gland. In: Bulletin of the Johns Hopkins Hospital , 38, 1926; Pp. 1-32.
  • Books by John Jacob Abel in the Internet Archive - online

literature

Web links

Individual evidence

  1. ^ Winfried R. Pötsch, Annelore Fischer, Wolfgang Müller, with the collaboration of Heinz Cassenbaum: Lexicon of important chemists. VEB Bibliographisches Institut, Leipzig 1988, ISBN 3-323-00185-0 , p. 7 f.
  2. aspet.org: John J. Abel Award