Henri Kagan

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Henri Boris Kagan (born December 15, 1930 in Boulogne-sur-Seine , Hauts-de-Seine , France ) is a French chemist .

Life

Henri Kagan was born as the son of the engineer Alexandre Kagan and his wife Adeline Kagan, b. Celniker born. After attending school in Guéret , Sceaux and Paris , he studied at the Sorbonne . He graduated from the École nationale supérieure de chimie de Paris with a degree in physics and engineering around 1954 to join the Center national de la recherche scientifique (CNRS) as a researcher . In 1960 he received his doctorate from J. Jacques at the Collège de France , 1968 lecturer at the University of Paris-Süd and director of the laboratory for stereoselective synthesis . From 1973 he was Professor of Chemistry at the University of Paris-Süd before he retired in 1999.

Kagan worked in the fields of stereochemistry , organometallic chemistry and organic synthesis. He was involved in the development of stereoselective catalysis for the synthesis of chiral molecules . In 1971 he was able to generate a large excess of a chiral product for the first time in alkene hydrogenation with the help of a rhodium complex catalyst. Stereoselective catalysis is of great importance for the pharmaceutical industry and was awarded the 2001 Nobel Prize in Chemistry . The fact that Kagan was not taken into account caused such resentment among French scientists that the then French Science Minister Roger-Gérard Schwartzenberg wrote a letter to the Nobel Foundation.

On August 13, 1960, he married Claude Vignon, with whom he has three children: Sylvie, Véronique, Anne.

Publications

Kagan has published numerous articles in academic journals since 1955.

  • with Dang-Tuan-Phat: Asymmetric catalytic reduction with transition metal complexes. I. Catalytic system of rhodium (I) with (-) - 2,3-0-isopropylidene-2,3-dihydroxy-1,4-bis (diphenylphosphino) butane, a new chiral diphosphine . In: Journal of the American Chemical Society . Volume 94 (18), 1972, pp. 6429-6433.
  • with P. Girard and JL Namy: Divalent lanthanide derivatives in organic synthesis. 1. Mild preparation of samarium iodide and ytterbium iodide and their use as reducing or coupling agents . In: Journal of the American Chemical Society . 102 (8), 1980, pp. 2693-2698.
  • with JL Namy: Lanthanides in organic synthesis . In: Tetrahedron . Volume 42 (24), 1986, pp. 6573-6614.
  • with Olivier Riant: Catalytic asymmetric Diels Alder reactions . In: Chemical Reviews . 92 (5), 1992, pp. 1007-1019.
  • Organic stereochemistry . Thieme, Stuttgart 1977, ISBN 3-13-532801-5 (French: Stéréochimie organique . 1975)
  • Editor of the book series Stereochemistry. Fundamentals and methods . Thieme, Stuttgart 1977, 4 volumes

Awards

Memberships

literature

Web links

Individual evidence

  1. ^ Sally Goodman: French Nobel protest makes chemist a cause célèbre . In: Nature , Vol. 414, p. 239, November 15, 2001, doi: 10.1038 / 35104765 .
personal data
SURNAME Kagan, Henri
ALTERNATIVE NAMES Kagan, Henri Boris (full name)
BRIEF DESCRIPTION French chemist
DATE OF BIRTH December 15, 1930
PLACE OF BIRTH Boulogne-sur-Seine , Hauts-de-Seine , France