T. forsythia has been identified in atherosclerotic lesions. Lee et al. found that infecting mice with T. forsythia induced foam cell formation and accelerated the formation of atherosclerotic lesions.[3] It has also been isolated from women with bacterial vaginosis.[4]
^Cionca, N, et al. "Microbiologic testing and outcomes of full-mouth scaling and root planing with or without amoxicillin/metronidazole in chronic periodontitis." J Perio 2010;81:15-23.
^[LEE HR, JUN HK, & CHOI BK. (2014). Tannerella forsythia BspA increases the risk factors for atherosclerosis in ApoE(-/-) mice. Oral Diseases. 20, 803-8.]
A Metagenomic Approach to Characterization of the Vaginal Microbiome Signature in Pregnancy. Kjersti Aagaard, Kevin Riehle, Jun Ma, Nicola Segata, Toni-Ann Mistretta, Cristian Coarfa, Sabeen Raza, Sean Rosenbaum, Ignatia Van den Veyver, Aleksandar Milosavljevic, Dirk Gevers, Curtis Huttenhower, Joseph Petrosino, James Versalovic. PLoS ONE volume 7, issue 6. (2012) issn:1932-6203 doi 10.1371/journal.pone.0036466