Friedrich Bear

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Portrait of Friedrich Bär (Heidelberg, ca.1934)

Friedrich "Fritz" Bär , also Friedrich Baer (born June 11, 1908 in Meran , South Tyrol , † January 22, 1992 in Berlin-Wilmersdorf ), was an Austro-German chemist , physician and university professor .

Life

Origin and family

Friedrich Bär was born in 1908 in South Tyrol as the son of the ophthalmologist and later Vice Mayor of Meran Josef Alois Karl Bär (1874–1952) and Magdalena (Magda) Maria (born October 9, 1884 in Franzensfeste , South Tyrol ; † 1971), the youngest daughter of Franz Landtmann , born. His brother was the future director of the Bregenz Festival Ernst Bär (1919–1985). Friedrich Bär came from the Beer family , which later u. a. had settled in Andelsbuch . After the father's death, the mother moved from Meran to Bregenz , where a large part of the Bär family lived in the region.

Friedrich Bär was married to Gerda Pauling (1915-2010) from 1939. The couple had five children. In Berlin he lived for the last years of his life at Humboldtstrasse 13 , which belonged to the Pauling family.

Scientific career

Friedrich Bär grew up in Meran, where he also went to school. He first studied chemistry in Innsbruck , Munich and Freiburg and finally received his doctorate in 1935 under the later Nobel Prize winner Richard Kuhn in Heidelberg . From 1934 to 1936 he received a DFG grant to do research at the Kaiser Wilhelm Institute for Medical Research in Heidelberg. He then moved to the Robert Koch Institute in Berlin and became a scientific member there from 1940. He habilitated in 1946 at Hans Berger Castle at the Institute of Hygiene of the University of Jena , which he published jointly received his doctorate there in 1950 to Dr. med. and stayed in Jena until mid-1950 .

Because the GDR was founded , Friedrich Bär fled to West Berlin with his family . He found a job at the Max von Pettenkofer Institute of the Federal Health Office in Berlin-Dahlem , where he was appointed professor for the Department of Physiology and Pharmacology . Later he was head of the toxicology department .

In 1953 he became a private lecturer for food chemistry and later also for nutritional hygiene at the Technical University of Berlin , where he taught until 1969.

Until 1975 he was still working at the Max von Pettenkofer Institute. His successor at the Max von Pettenkofer Institute was Hartmut Uehleke.

Friedrich Bär died in Berlin-Wilmersdorf in 1992 at the age of 83. His grave is in the Kaiser Wilhelm Memorial Cemetery in Berlin-Westend .

Scientific importance

Working at Richard Kuhn

Friedrich Bär published experimental results together with Richard Kuhn in 1934/35. The following well-known scientists have referred to this work as an example in their books:

Working at Hans Schlossberger

In 1937 he carried out the experiments that led to joint publication with Hans Schlossberger in 1938. Friedrich Bär found experimentally that Prontosil mice infected with lymphogranuloma inguinale could positively influence the course of the disease and mortality usually 6–10 days after the onset of typical symptoms. These findings formed the basis for further work in the field of sulfonamide preparations.

He also carried out the experiments with comparable substances such as sulfapyridine and sulfathiazole , and came to the conclusion that Uliron (Diseptale A) was the most effective preparation in the series. The comparison substances used for the experiment were the basis for follow-up research by other scientists, such as John Callomon . After 10 comparison substances were examined by Friedrich Bär.

The experiments also showed that the virus can still be detected in the brains of infected monkeys and mice for a long time. Based on this, he carried out further experiments with other viral pathogens.

Use of pesticides

In his publications, Friedrich Bär always pointed out the risks involved in using pesticides on food. As early as 1973, in a Spiegel article on the use of pesticides in food production, he expressed his concerns about using arithmetic values ​​to adjust the limit values ​​to a maximum tolerance value without taking into account the influence of “residue levels” on the consumer.

Bär was in the Commission for Plant Protection, Plant Treatment and Storage Preservatives of the German Research Foundation (DFG) . In 1975, together with eleven other well-known toxicologists , he published a memorandum on Toxicology for the DFG , which has been published as a continuous publication until now.

Other scientific topics

In his career, Friedrich Bär has made numerous, recited publications on the following topics:

  • Health hazard to humans and animals from insecticides , residues and detection of insecticides in food
  • Nutritional hygiene
  • Plastics in medicine and in the context of the food law

He also appeared as an expert for the DFG and in the German Bundestag, z. B. 1971 on the subject of air pollution and its dangers in the course of the gasoline lead law .

In 1974, his doctoral candidate Christhard Böhme and later Professor Werner Grunow dedicated a publication to him in the Archives of Toxicology for his 65th birthday .

Works (selection)

  • Together with Richard Kuhn on the migration of hydrogen in Liebigs Ann. Chem. 516, 143, 1925
  • Together with Richard Kuhn on experiments on hydroxyl groups, reports of the German Chemical Society , 67, 898, 1934
  • Together with Richard Kuhn on quinophthalones in Liebigs Ann. Chem. 516, 155, 1935
  • Chemotherapeutic attempts in the experimental infection of the mouse with lymphogranuloma venereum . In: Klinische Wochenschrift 17, 1938
  • Experiences and results about the chemotherapeutic influence of the lymphogranuloma inguinale and other viral diseases . In: Zeitschrift für Immunitätsforschung 97, 1940
  • Chemotherapeutic experiments with penicillin , Journal for Hygiene and Infectious Diseases, Volume 129, Verlag Von Veit & Comp., 1949, pp. 2 ff.
  • Chemotherapy of trypanosomes infeklionen , Chemisches Zentralblatt ff, Volume 120, Part 1, pp 322nd
  • Habilitation thesis: About the possibility of therapeutically influencing neurotropic virus types: Chemotherapeutic experiments in the experimental infection of the mouse with " Louping ill " (jumping disease of sheep) , Jena, 1950
  • Antivitamin Effect of Plant Substances, Planta Medica , 2 (1), 1954, pp. 23-28
  • Pesticides, their effects on food and their detection . In: Journal of Food Research and Research , Volume 105, Issue 2, 1957, pp. 104–121
  • Together with K. Raible: General investigation procedures and laboratory technology , magazine for food investigation and research, Volume 105, Issue 2, 1957, pp. 129-129
  • Together with Günter Scheibe , KE Schulte, Oelkers, Karl-Ernst Quentin : Frontier areas of food science , magazine for food analysis and research, Volume 108, Issue 1, 1958, pp. 75–76
  • Together with F. Griepentrog: The situation in the health assessment of flavoring agents for food , medicine and nutrition, volumes 7–8, Pallas-Verlag , 1966, pp. 244–250
  • Together with R. Roll: Studies on the teratogenic effects of hydroxyurea during the early and embryonic development of the mouse , Archiv für Toxikologie , Volume 25, Issue 2, 1969, pp. 150-168
  • The hygienic-toxicological assessment within the framework of the Food Act in relation to environmental toxicology , Deutsche Lebensmittel-Rundschau , Wissenschaftliche Verlagsgesellschaft, 1971, p. 389 ff.
  • Together u. a. with Wolfgang Bruns , Hans-Jürgen Hapke, Dietrich Henschler , Otto Rudolf Klimmer, Herbert Remmer , Wolfgang Wirth : Memorandum of Toxicology , German Research Foundation, Harold Boldt Verlag KG, Boppard, 1975

Award

Individual evidence

  1. ↑ Meraner Zeitung . No. 85 , July 15, 1908, p. 7 .
  2. ↑ a b c d e f August Ludwig Degener, Walter Habel: Who is who? Ed .: Arani. tape 15 , 1967, p. 51 .
  3. ↑ Hans Schlossberger, Friedrich Bär: Studies on the mode of action of sulfonamide compounds in the infection of mice with streptococci and lymphogranuloma inguinale . In: G. Fischer (Hrsg.): Zentralblatt für Bakteriologie, Parasitenkunde, Infectious diseases and hygiene: Medical-hygienic, bacteriology, virus research and parasitology . tape 144 , 1939, pp. 228 ff .
  4. ↑ Jena University Archives. (PDF) p. 109 , accessed on November 4, 2017 .
  5. ^ Fischer, Wolfram., Academy of Sciences (Berlin, West). Working group Exodus of sciences from Berlin .: Exodus of sciences from Berlin: Questions - Results - Desiderata: Development before and after 1933 . de Gruyter, Berlin [a. a.] 1994, ISBN 3-11-013945-6 , pp. 421 .
  6. ↑ a b Friedrich Bär: Testing for physiological and toxic effects . In: Nitsche / Wolf (Ed.): Kunststoffe structure, physical behavior and testing: Volume 1: Structure and physical behavior of plastics . Springer, Berlin, Heidelberg 1961, ISBN 978-3-642-45972-6 .
  7. ^ A b Johann Christian Poggendorff, Hans Wussing, Margot Köstler (eds.): Biographical-literary concise dictionary for the history of the exact sciences . tape 8 , 1, Installment 3rd Saxon Academy of Sciences in Leipzig, 1996, p. 190 .
  8. ↑ T. Steinkopff: Central Pharmaceutical Hall for Germany . tape 92 , 1953, pp. 73 .
  9. ↑ University news of the TU Berlin. Retrieved November 4, 2017 .
  10. ^ Hans-Jürgen Mende : Lexicon of Berlin burial places . Pharus-Plan, Berlin 2018, ISBN 978-3-86514-206-1 , p. 471.
  11. ↑ Friedrich Weygand: Synthesis of lactoflavin (vitamin B2) and other flavins . Johann Wolfgang Goethe University in Frankfurt am Main., 1936, p. 7 ( google.de [accessed on April 10, 2018]).
  12. ↑ Leopold Ruzicka, Wilhelm Otto Stepp, Sir Edward Mellanby: Results of vitamin and hormone research . Academic publishing company m. b. h., 1944, p. 405 ( google.de [accessed April 10, 2018]).
  13. ↑ Walter Hückel: Theoretical Foundations of Organic Chem . Geest & Portig, 1957, p. 305 ( google.de [accessed April 10, 2018]).
  14. ^ Karl Winnacker, Leopold Küchler: Chemical Technology: Organic Technology I-II . C. Hanser, 1960, p. 113 ( google.de [accessed April 10, 2018]).
  15. ^ Fritz Ullmann, Wilhelm Foerst: Encyclopedia of technical chemistry . Urban & Schwarzenberg, 1963, p. 332 ( google.de [accessed April 10, 2018]).
  16. ^ Josef Houben, Eugen Müller, Theodor Weyl: Methods of organic chemistry (Houben-Weyl): nitrogen compounds I. (4 v.) . G. Thieme, 1965, p. 490 ( google.de [accessed April 10, 2018]).
  17. ^ Leopold Gmelin: Silver: Main volume . Verlag Chemie, 1975, p. 173 ( google.de [accessed April 10, 2018]).
  18. ↑ Hans Schuermann, Arthur Leinbrock: Sexually transmitted diseases . Springer-Verlag, 2013, ISBN 978-3-642-94892-3 , pp. 663 ( google.de [accessed April 10, 2018]).
  19. ^ R. Doerr, LO Kunkel: Handbook of virus research: I. Supplementary volume . Springer-Verlag, 2013, ISBN 978-3-7091-9790-5 , pp. 305 ( google.de [accessed April 10, 2018]).
  20. ↑ Hans Schuermann, Arthur Leinbrock: Sexually transmitted diseases . Springer-Verlag, 2013, ISBN 978-3-642-94892-3 , pp. 670 ( google.de [accessed April 10, 2018]).
  21. ^ R. Doerr, LO Kunkel: Handbook of virus research: I. Supplementary volume . Springer-Verlag, 2013, ISBN 978-3-7091-9790-5 , pp. 304 ( google.de [accessed April 10, 2018]).
  22. ^ Wilhelm Kolle, Heinrich Hetsch, Hans Schlossberger: Kolle and Hetsch Experimental Bacteriology and Infectious Diseases: with special consideration of immunity . Urban & Schwarzenberg, 1942, p. 746 ( google.de [accessed April 10, 2018]).
  23. ↑ Use of pesticides in food production. In: Spiegel. 1973, Retrieved November 3, 2017 .
  24. ^ Memorandum on Toxicology. (PDF) German Research Foundation, 2000, accessed April 4, 2018 .
  25. ↑ Friedrich Bär: Feeding experiments with Systox-treated sugar beets . In: drug research . No. 4 , 1954.
  26. ↑ Friedrich Bär: Health hazard from chemical pesticides . In: Scoreboard for pest science . tape 29 , no. 6 , 1956, pp. 85-87 .
  27. ↑ Friedrich Bär: Veterinary drugs and rearing agents in agricultural practice: Health considerations for the protection of the consumer when using veterinary drugs and rearing agents in agricultural practice . In: Medicine and Nutrition . Volumes 3-4. Pallas Verlag, 1962, p. 94 ff .
  28. ↑ Friedrich Bär: The evidence of insecticides in food and the importance for health . In: German Medical Journal . tape 15 , 1964, pp. 672-680 .
  29. ↑ Friedrich Bär: The toxicological assessment (safety margins, maximum quantities) within the framework of the food law (food additives and pesticide residues) . In: Archives of Toxicology . tape 32 , no. 1 , March 1, 1974, ISSN  0340-5761 , p. 51-62 , doi : 10.1007 / BF00334611 ( springer.com [accessed April 3, 2018]).
  30. ↑ Friedrich Bär: Chemotherapeutic experiments with penicillin in the experimental infection of the mouse with pig rot . In: Journal of Hygiene and Infectious Diseases . tape 129 . Veit & Comp., 1949.
  31. ↑ W. Grunow, F. Bär: Residues of drugs in food of animal origin. In: Medical monthly . No. 22 , 1963.
  32. ↑ Chr Böhme, W. Grunow: About the metabolism of 4- (2.4.5-trichlorophenoxy) -butyric acid in rats . In: Archives of Toxicology . tape 32 , no. 3 , September 1, 1974, ISSN  0340-5761 , p. 227–231 , doi : 10.1007 / BF00318437 ( springer.com [accessed April 4, 2018]).
personal data
SURNAME Bear, Friedrich
ALTERNATIVE NAMES Bär, Fritz (nickname); Baer, ​​Friedrich
BRIEF DESCRIPTION Austro-German chemist, physician and university professor
DATE OF BIRTH June 11, 1908
PLACE OF BIRTH Meran , South Tyrol
DATE OF DEATH January 22, 1992
Place of death Berlin-Wilmersdorf