Martin Chalfie

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Martin Chalfie
George W. Bush meets three 2008 Nobel Prize winners. Martin Chalfie is second from right.

Martin Chalfie (born January 15, 1947 in Chicago , Illinois ) is an American biologist and, together with Osamu Shimomura and Roger Tsien, winner of the 2008 Nobel Prize in Chemistry .

Life

Chalfie received his PhD in Physiology from Harvard University in 1977 . In 1982 he became an associate professor of biology at Columbia University . He later became William R. Kenan Jr. Professor of Biology at the same university.

Chalfie works in the field of cell differentiation . He is particularly interested in the development and function of nerve cells, which he examined using the example of the nematode Caenorhabditis elegans . He also developed new experimental methods for these investigations. In 1994 he was able to express the gene for the green fluorescent protein for the first time outside of the jellyfish Aequorea victoria . This was the breakthrough for protein as a genetic marker .

Chalfie is married to Tulle Hazelrigg, who is also a professor at Columbia University, and has one daughter.

publication

  • Martin Chalfie and Steven Kain: Green Fluorescent Protein. Properties, Applications and Protocols . 2nd edition, Wiley & Sons, Hoboken 2006, ISBN 0-471-73682-1

Awards

Memberships

literature

Web links

Commons : Martin Chalfie  - Collection of images, videos and audio files

Individual evidence

  1. M. Chalfie, Y. Tu, G. Euskirchen, WW Ward, DC Prasher : Green fluorescent protein as a marker for gene expression . In: Science . Volume 263, 1994, pp. 802-805