Tomas Lindahl
Tomas Robert Lindahl (born January 28, 1938 in Stockholm ) is a Swedish cancer researcher. He has made particular contributions to research into the biochemistry of DNA repair . In 2015 he was awarded the Nobel Prize in Chemistry “for the mechanistic studies on DNA repair” together with Paul Modrich and Aziz Sancar .
Life
Lindahl was founded in 1967 at the Karolinska Institute in Solna in Stockholm with the work on the structure and stability of nucleic acids in solution doctorate and became in 1970 an MD just there. As a postdoctoral fellow , he worked at Princeton University in Princeton , New Jersey (1964–1967) and at Rockefeller University in New York City , New York (1967–1969). From 1969 to 1977 he worked at the Karolinska Institute and from 1978 to 1981 he was Professor of Medical Biochemistry at the University of Gothenburg . Since 1981 he has been researching for the Imperial Cancer Research Fund (later Cancer Research UK ) in London. He retired in 2009, but is now Emeritus group leader at the Francis Crick Institute and Emeritus director of Cancer Research UK at Clare Hall Laboratory, Hertfordshire.
While DNA was thought to be a relatively stable molecule until the early 1970s , Lindahl found that DNA is so unstable that life based on DNA should actually be impossible. While searching for stabilization mechanisms in DNA, he found base excision repair (BER) as the DNA repair mechanism (see DNA repair ).
Awards (selection)
- 1988 membership in the Royal Society
- 2007 Royal Medal
- 2008 Prix Étranger de l'INSERM
- 2010 Copley Medal
- 2015 Nobel Prize in Chemistry
- 2017 Fellow of the American Association for the Advancement of Science
- 2018 membership in the National Academy of Sciences
- Membership in the Norwegian Academy of Sciences
- Membership in the Royal Swedish Academy of Sciences
- Membership in the Academia Europaea
literature
- Who's Who 2012 . 164th edition. A & C Black, London 2011, ISBN 978-1-4081-4229-5 , pp. 1382 .
Web links
- Profile ( memento of February 23, 2012 in the Internet Archive ) at Cancer Research UK (london-research-institute.co.uk)
Individual evidence
- ↑ libris.kb.se ; Retrieved May 21, 2011
- ^ Nobel Prize in Chemistry 2015, press release, accessed October 7, 2015
- ^ Fellows ( memento October 7, 2010 in the Internet Archive ) of the Royal Society (royalsociety.org); Retrieved May 21, 2011
- ^ Royal Medal ( memento June 19, 2010 in the Internet Archive ) of the Royal Society (royalsociety.org); Retrieved May 21, 2011
- ^ Prix 2008 / Histoire de l'Inserm. In: histoire.inserm.fr. Retrieved February 5, 2016 (French).
- ^ Royal Society recognizes excellence in science ( Memento of June 13, 2010 in the Internet Archive ) of the Royal Society (royalsociety.org); Retrieved May 21, 2011
- ↑ http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2015/lindahl-facts.html
- ^ Fellows of the AAAS: T. Lindahl. American Association for the Advancement of Science, accessed February 1, 2018 .
- ↑ dnva.no ; Retrieved May 21, 2011
- ↑ kva.se ; Retrieved May 21, 2011
- ↑ ae-info.org ; Retrieved May 21, 2011
| personal data | |
|---|---|
| SURNAME | Lindahl, Tomas |
| ALTERNATIVE NAMES | Lindahl, Tomas R .; Lindahl, Tomas Robert (full name) |
| BRIEF DESCRIPTION | Swedish cancer researcher |
| DATE OF BIRTH | January 28, 1938 |
| PLACE OF BIRTH | Stockholm |