Bill Naughton and Johannes Fibiger: Difference between pages

From Wikipedia, the free encyclopedia
(Difference between pages)
Content deleted Content added
 
m →‎References: Added reflist and erased redundant ref
 
Line 1: Line 1:
{{Infobox Scientist
'''William John Francis Naughton''', or '''Bill Naughton''' ([[Ballyhaunis]], [[12 June]] [[1910]] - [[Ballasalla]], [[9 January]] [[1992]]) was a [[United Kingdom|British]] [[playwright]] and [[author]], best known for his play ''[[Alfie (play)|Alfie]]''.
|name = Johannes Andreas Grib Fibiger
|box_width =
|image =J_Fibiger.jpg
|image_width =150px
|caption =Fibiger won a Nobel Prize in 1926
|birth_date = [[April 23]], [[1867]]
|birth_place = [[Silkeborg]]
|death_date = [[January 30]], [[1928]]
|death_place = [[Copenhagen]]
|residence =
|citizenship =
|nationality = [[Denmark|Danish]]
|ethnicity =
|field =
|work_institutions =
|alma_mater =
|doctoral_advisor =
|doctoral_students =
|known_for = [[cancer]]
|author_abbrev_bot =
|author_abbrev_zoo =
|influences =
|influenced =
|prizes = 1926 [[Nobel Prize in Physiology or Medicine]]
|religion =
|footnotes =
|signature =
}}
'''Johannes Andreas Grib Fibiger''' ([[April 23]], [[1867]] [[Silkeborg]] - [[January 30]], [[1928]] [[Copenhagen]]) was a [[Denmark|Danish]] scientist who won the 1926 [[Nobel Prize in Physiology or Medicine]]. Fibiger had claimed to find an organism he called ''[[Spiroptera carcinoma]]'' that caused [[cancer]] in [[mouse|mice]] and [[rat]]s. Later, it was shown that this specific organism was not the primary cause of the tumors. Because of this, some consider Fibiger's Nobel Prize to be undeserved, but others credit Fibiger with showing that external stimuli can induce cancer.


==Research==
Born in Ballyhaunis, [[County Mayo]],Ireland his family moved in 1914 to [[Bolton]], [[Lancashire]], [[England]], where he attended Saint Peter and Paul's School. Naughton worked as a weaver, coal-bagger and lorry-driver before he started writing. Naughton's preferred environment was working class society. Although ''Alfie'' is the play with which he will always be associated, mostly because of the British film starring Michael Caine in the eponymous role, he was a prolific writer, with both plays, novels, short stories and children’s books to his name. At least two of his other plays have been transferred onto the cinema screen as well. These are ''[[Spring and Port Wine]]'', which had [[James Mason]] starring in the role of Rafe Crompton, and ''[[The Family Way]]'', which starred [[John Mills]]. His work also includes the novel ''One Small Boy'' (1957), and the collection of short stories ''The Goalkeeper's Revenge: And Other Stories'' (1961).
While studying [[tuberculosis]] in lab rats, Fibiger found [[tumor]]s in some of his rats. He discovered that these tumors were associated with parasitic [[nematode]] worms that had been living in some [[cockroach]]es that the rats had eaten. He thought that these organisms may have been the cause of the cancer. In fact, the rats had been suffering from a [[vitamin A]] deficency and this was the main cause of the tumors. The parasites had merely caused the tissue irritation that drove the damaged cells into cancer; any tissue irritation could have induced the tumors. Although the specific link between the parasites and cancer was later known to be relatively unimportant, the idea that tissue damage was a cause of cancer was still an important advance in cancer research.
Had many of his plays performed at the Octagon Theatre in Bolton town Centre and has a theatre named after him.


One of his experiments from 1998 is by some regarded as the first controlled [[clinical trial]].<ref>{{Cite journal
During his lifetime, he received the following awards:
| author = [[A. Hrobjartsson]], [[P. C. Gotzsche]] & [[C. Gluud]]
*Screenwriters Guide Award (1967 and 1968)
| title = The controlled clinical trial turns 100 years: Fibiger's trial of serum treatment of diphtheria
*Italia Prize for Radio Play (1974)
| journal = [[BMJ]]
*Children's Rights Workshop Other Award (1978)
| volume = 317
*Portico Literary Prize (1987)
| issue = 7167
*The Hon. Fellowship, Bolton Institute of Higher Education (1988).
| pages = 1243–1245
| year = 1998
| month = October
| pmid = 9794873
}}</ref>


==Biography==
Naughton died in 1992, in Ballasalla on the [[Isle of Man]]. There is today a "Bill Naughton Short Story Competition"[http://www.aghamoreireland.com/kennynaughton/shortstory.htm] in honour of the author. This is administered by The Kenny/Naughton Autumn School, established in 1993 and based today in the village of [[Aghamore]], Ireland. The "School" was created in honour of Bill Naughton and [[Patrick Dermot Kenny]], and scheduled over the annual October bank holiday weekend, consists of lectures, readings, local tours, workshops, new publications, drama and entertainment[http://www.aghamoreireland.com/kennynaughton/school.htm].
Fibiger became a medical doctor in 1890 and studied under [[Robert Koch]] and [[Emil Adolf von Behring]] in Berlin. He received his research doctorate from the [[University of Copenhagen]] in 1895 and became a professor there.


==Plays==
==References==
{{Reflist}}


=== Further reading ===
* ''My Flesh, My Blood'' (1957)
*''Nobel Lectures, Physiology or Medicine 1922-1941'', Elsevier Publishing Company, Amsterdam, 1965.
* ''[[Alfie (play)|Alfie]]'', ([[Alfie (1966 film)|1966 film]]) (1963)
*{{Citation
* ''[[The Family Way|All In Good Time]]'' (1963)
|id = [[PMID]]:11500602
* ''He Was Gone When We Got There'' (1966)
|url= http://www.ncbi.nlm.nih.gov/pubmed/11500602
* ''June Evening'' (1966)
|last=Modlin
* ''[[Spring and Port Wine]]'' (1967)
|first=I M
* ''Lighthearted Intercourse'' (1971)
|last2=Kidd
* ''Keep It In The Family'' (1967)
|first2=M
* ''Annie And Fanny'' (1967)
|last3=Hinoue

|first3=T
Naz likes you hahhahahahahaha
|publication-date=2001 Sep
|year=2001
|title=Of Fibiger and fables: a cautionary tale of cockroaches and Helicobacter pylori.
|volume=33
|issue=3
|periodical=J. Clin. Gastroenterol.
|pages=177-9
}}
*{{Citation
|id = [[PMID]]:9889652
|url= http://www.ncbi.nlm.nih.gov/pubmed/9889652
|last=Gluud
|first=C N
|publication-date=1998 Dec 14
|year=1998
|title=[Centenary of Fibiger's controlled clinical trial]
|volume=160
|issue=51
|periodical=Ugeskr. Laeg.
|pages=7407-8
}}
*{{Citation
|id = [[PMID]]:9843145
|url= http://www.ncbi.nlm.nih.gov/pubmed/9843145
|last=Raju
|first=T N
|publication-date=1998 Nov 14
|year=1998
|title=The Nobel chronicles. 1926: Johannes Andreas Grib Fibiger (1867-1928).
|volume=352
|issue=9140
|periodical=[[Lancet]]
|pages=1635
}}
*{{Citation
|id = [[PMID]]:1558350
|url= http://www.ncbi.nlm.nih.gov/pubmed/1558350
|last=Stolley
|first=P D
|last2=Lasky
|first2=T
|publication-date=1992 May 1
|year=1992
|title=Johannes Fibiger and his Nobel Prize for the hypothesis that a worm causes stomach cancer.
|volume=116
|issue=9
|periodical=Ann. Intern. Med.
|pages=765-9
}}


==External links==
==External links==
*[http://www.nobel.se/medicine/laureates/1926/fibiger-bio.html Nobel Prize Biography]
{{imdb name|id=0622540|name=Bill Naughton}}
*[http://www.whonamedit.com/doctor.cfm/1443.html Biography from WhoNamedIt]

{{Nobel Prize in Physiology or Medicine Laureates 1926-1950}}

{{DEFAULTSORT:Fibiger, Johannes}}
[[Category:1867 births|Fibiger, Johannes]]
[[Category:1928 deaths|Fibiger, Johannes]]
[[Category:Nobel laureates in Physiology or Medicine|Fibiger, Johannes]]
[[Category:Danish Nobel laureates|Fibiger, Johannes]]
[[Category:Danish scientists|Fibiger, Johannes]]
[[Category:Danish physicians]]
[[Category:University of Copenhagen alumni]]
[[Category:University of Copenhagen faculty]]


[[ar:يوهانس فيبيغر]]
{{DEFAULTSORT:Naughton, Bill}}
[[ca:Johannes Andreas Grib Fibiger]]
[[Category:English dramatists and playwrights]]
[[da:Johannes Fibiger]]
[[Category:People from Bolton]]
[[Category:1910 births]]
[[de:Johannes Fibiger]]
[[es:Johannes Andreas Grib Fibiger]]
[[Category:1992 deaths]]
[[fr:Johannes Andreas Grib Fibiger]]
[[hr:Johannes Andreas Grib Fibiger]]
[[id:Johannes Andreas Grib Fibiger]]
[[it:Johannes Andreas Grib Fibiger]]
[[sw:Johannes Fibiger]]
[[nl:Johannes Andreas Grib Fibiger]]
[[ja:ヨハネス・フィビゲル]]
[[no:Johannes Andreas Grib Fibiger]]
[[pl:Johannes Fibiger]]
[[pt:Johannes Andreas Grib Fibiger]]
[[ro:Johannes Fibiger]]
[[ru:Фибигер, Йоханнес Андреас Гриб]]
[[sv:Johannes Fibiger]]
[[vi:Johannes Fibiger]]
[[zh:約翰尼斯·菲比格]]

Revision as of 14:10, 10 October 2008

Johannes Andreas Grib Fibiger
Fibiger won a Nobel Prize in 1926
BornApril 23, 1867
DiedJanuary 30, 1928
NationalityDanish
Known forcancer
Awards1926 Nobel Prize in Physiology or Medicine

Johannes Andreas Grib Fibiger (April 23, 1867 Silkeborg - January 30, 1928 Copenhagen) was a Danish scientist who won the 1926 Nobel Prize in Physiology or Medicine. Fibiger had claimed to find an organism he called Spiroptera carcinoma that caused cancer in mice and rats. Later, it was shown that this specific organism was not the primary cause of the tumors. Because of this, some consider Fibiger's Nobel Prize to be undeserved, but others credit Fibiger with showing that external stimuli can induce cancer.

Research

While studying tuberculosis in lab rats, Fibiger found tumors in some of his rats. He discovered that these tumors were associated with parasitic nematode worms that had been living in some cockroaches that the rats had eaten. He thought that these organisms may have been the cause of the cancer. In fact, the rats had been suffering from a vitamin A deficency and this was the main cause of the tumors. The parasites had merely caused the tissue irritation that drove the damaged cells into cancer; any tissue irritation could have induced the tumors. Although the specific link between the parasites and cancer was later known to be relatively unimportant, the idea that tissue damage was a cause of cancer was still an important advance in cancer research.

One of his experiments from 1998 is by some regarded as the first controlled clinical trial.[1]

Biography

Fibiger became a medical doctor in 1890 and studied under Robert Koch and Emil Adolf von Behring in Berlin. He received his research doctorate from the University of Copenhagen in 1895 and became a professor there.

References

  1. ^ A. Hrobjartsson, P. C. Gotzsche & C. Gluud (1998). "The controlled clinical trial turns 100 years: Fibiger's trial of serum treatment of diphtheria". BMJ. 317 (7167): 1243–1245. PMID 9794873. {{cite journal}}: Unknown parameter |month= ignored (help)

Further reading

External links