Georges JF Koehler

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Georges Jean Franz Köhler (born April 17, 1946 in Munich ; † March 1, 1995 in Freiburg im Breisgau ) was a German biologist and Nobel Prize winner .

After graduating from high school in Kehl , Köhler began studying biology at the University of Freiburg im Breisgau in 1965 , which he graduated with a diploma in 1971. He then worked as a doctoral student at the Roche Institute for Immunology in Basel with Fritz Melchers on the enzymology of the immune system . In 1974 he received his doctorate from the University of Freiburg. rer. nat.

From 1974 to 1976 Köhler was a postdoctoral fellow at the British Medical Research Council at the Laboratory of Molecular Biology in Cambridge (UK) in César Milstein's group. There, together with Milstein, he discovered the possibility of forming monoclonal antibodies from hybridoma cells through cell fusion of B lymphocytes with myeloma cells .

From 1976 to 1984 Köhler worked again at the Institute for Immunology in Basel before he was appointed director at the Max Planck Institute for Immunobiology in Freiburg in 1984 . In 1984 he became a professor at the University of Freiburg.

In 1981 Köhler received a Gairdner Foundation International Award . In 1984 he received the Nobel Prize for Physiology or Medicine together with César Milstein and Niels K. Jerne and in the same year the Albert Lasker Award for Basic Medical Research . In 1985 Köhler was appointed a member of the Leopoldina .

Georges Köhler died of pneumonia . The street at the technical faculty of the University of Freiburg is named Georges-Köhler-Allee in his honor. The German Society for Immunology awards the Georges Köhler Prize.

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Individual evidence

  1. ↑ Köhler, G. & Milstein, C. (1975): Continuous cultures of fused cells secreting antibody of predefined specificity. In: Nature. Vol. 256, pp. 495-497. PMID 1172191 doi : 10.1038 / 256495a0 Reprint In: J. Immunol. Vol. 174, pp. 2453-2455. PMID 15728446 PDF
  2. ↑ Margulies, DH (2005): Monoclonal antibodies: producing magic bullets by somatic cell hybridization. In: J. Immunol. Vol. 174, pp. 2451-2452. PMID 15728445 PDF
  3. ↑ Information from the Nobel Foundation on the 1984 award ceremony to Georges JF Köhler (English)
  4. ^ Georges Köhler Prize of the German Society for Immunology (dgfi.org); Retrieved October 20, 2012
personal data
SURNAME Koehler, Georges JF
ALTERNATIVE NAMES Köhler, Georges Jean Franz (full name)
BRIEF DESCRIPTION German biologist and Nobel Prize winner
DATE OF BIRTH April 17, 1946
PLACE OF BIRTH Munich
DATE OF DEATH March 1, 1995
Place of death Freiburg in Breisgau