John Robert Vane
Sir John Robert Vane (born March 29, 1927 in Tardebigge , Worcestershire , † November 19, 2004 in Farnborough , London ) was a British biochemist , pharmacologist and Nobel Prize winner in medicine . He was the discoverer of the mode of action of acetylsalicylic acid on prostaglandins .
Life
His father Maurice Vane was the son of Russian immigrants; his mother Frances Vane came from a British farming family. He went to King Edward's School in Birmingham . At the age of twelve he got a chemistry kit from his parents and began to experiment. He studied chemistry from 1944 at the University of Birmingham . There he was initially disappointed by the lack of opportunities to experiment . He then studied from 1946 at the University of Oxford pharmacology with Harold Burn , where he received his doctorate in 1953 at the Nuffield Institute for Medical Research with Geoffrey Dawes after an interim teaching activity at the University of Sheffield . From 1953 he was an assistant professor at Yale University . From 1955 he taught at the Institute for Basic Medical Science at the University of London in the Royal College of Surgeons of England , first as Senior Lecturer, then as Reader and finally as Professor of Experimental Pharmacology. In 1973 he became director of research at the Wellcome Foundation . From 1985 he was at the William Harvey Research Institute at the Medical College of St. Bartolomew Hospital in London.
He received the Nobel Prize for Medicine in 1982 together with Sune Bergström and Bengt Samuelsson for discoveries relating to prostaglandins and related biologically active substances. In the late 1960s and early 1970s, he discovered that aspirin works by suppressing prostaglandin synthesis. He also worked with the Brazilian pharmacologist Sérgio Henrique Ferreira , also in the field of the early development of ACE inhibitors (which led to the development of captopril in 1974 at the pharmaceutical company Squibb ).
In 1977 he received the Albert Lasker Award for Basic Medical Research and in 1989 the Royal Medal of the Royal Society , of which he had been a Fellow since 1974. In 1984 he was knighted as a Knight Bachelor . He was a foreign member of the Polish Academy of Sciences , the Royal Netherlands Academy of Sciences , the American Academy of Arts and Sciences (1982) and the National Academy of Sciences (1983). He has received several honorary doctorates (Mount Sinai Hospital Medical School in New York, Krakow, Paris, Aberdeen). In 1980 he received the Peter Debye Prize and in 1981 he was a Dale Medalist.
Vane was married and had two daughters.
literature
- Gisela Baumgart: Vance, John Robert Sir. In: Werner E. Gerabek , Bernhard D. Haage, Gundolf Keil , Wolfgang Wegner (eds.): Enzyklopädie Medizingeschichte. De Gruyter, Berlin / New York 2005, ISBN 3-11-015714-4 , p. 1435 f.
Web links
- Information from the Nobel Foundation on the 1982 award ceremony for John Robert Vane
Individual evidence
- ↑ Joe Collier: Obituary: Sir John Vane. In: theguardian.com. November 25, 2004, accessed January 15, 2017 .
- ↑ John R. Vane - Biographical. In: nobelprize.org. November 19, 2004, accessed January 15, 2017 .
- ^ William Harvey Research Foundation, William Harvey Research Institute. (No longer available online.) In: whrf.org.uk. Archived from the original on September 8, 2014 ; accessed on January 15, 2017 . Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice.
- ↑ Joe Collier: Obituary: Sir John Vane. In: theguardian.com. November 25, 2004, accessed January 15, 2017 .
| personal data | |
|---|---|
| SURNAME | Vane, John Robert |
| BRIEF DESCRIPTION | British biochemist and Nobel Prize in Medicine |
| DATE OF BIRTH | March 29, 1927 |
| PLACE OF BIRTH | Tardebigge , Worcestershire |
| DATE OF DEATH | November 19, 2004 |
| Place of death | Farnborough , London |