Rolf Zinkernagel

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Rolf Zinkernagel.

Rolf Martin Zinkernagel (born January 6, 1944 in Riehen , Basel-Stadt ) is a Swiss physician and experimental immunologist . He is a Nobel Prize Winner in Medicine (1996).

Life

Zinkernagel studied medicine from 1962 to 1968 and received his doctorate in 1970 from the University of Basel with a subject on clinical neurology. He is a member of the Zofingia . From October 1970 to 1973 he worked as a research assistant at the Institute for Biochemistry at the University of Lausanne. In 1975 he received his Ph. D. at the Australian National University in Canberra and also completed his habilitation there. From 1976 to 1979 he was a professor at the Scripps Research Institute , then he went to the University of Zurich , where he stayed until 1992. He later worked at the Institute for Experimental Immunology at the University Hospital Zurich . In February 2008, Rolf Zinkernagel retired.

Together with the Australian Peter Doherty , he discovered in 1973 how the immune system recognizes virus-infected cells. For this realization, both received the Nobel Prize for Medicine in 1996. Virus-infected cells are recognized and destroyed by the immune system using killer T cells . With Doherty he discovered mice infected with meningitis viruses that these killer T cells not only need a virus antigen to recognize virus-infected cells , but also the MHC complexes, which were previously known to be involved in tissue rejection Transplants play a role. Their role in the immune defense against viruses was surprising.

Zinkernagel is thus the 24th Swiss Nobel Prize winner. In 1981 he received the Cloëtta Prize . In 1983, Zinkernagel received the Paul Ehrlich and Ludwig Darmstaedter Prize , the Gairdner Foundation International Award in 1986 , the William B. Coley Award in 1987 , the Otto Naegeli Prize in 1988 and the Albert Lasker Award for Basic Medical Research in 1995 . Since 1994 he has been a member of the German Academy of Sciences Leopoldina (since 2008 National Academy of Sciences). In 1989 he was accepted as a full member of the Academia Europaea . In 1996, Zinkernagel was elected to the National Academy of Sciences , 1998 to the American Academy of Arts and Sciences, and 2001 to the American Philosophical Society .

literature

  • Gisela Baumgart: Zinkernagel, Rolf. In: Encyclopedia of Medical History. Edited by Werner E. Gerabek , Bernhard D. Haage, Gundolf Keil and Wolfgang Wegner, Walter de Gruyter, Berlin and New York 2005, p. 1530
  • Rolf Zinkernagel: Viruses and Virus Like Agents in Disease. Basel 1993.

Web links

Commons : Rolf Zinkernagel  - Collection of images, videos and audio files

Individual evidence

  1. ↑ http://www.uzh.ch/news/articles/2008/2843.html
  2. ↑ Directory of members: Rolf Zinkernagel. Academia Europaea, accessed on August 16, 2017 .
  3. ↑ Member History: Rolf M. Zinkernagel. American Philosophical Society, accessed December 12, 2018 .
personal data
SURNAME Zinkernagel, Rolf
ALTERNATIVE NAMES Zinkernagel, Rolf Martin (full name)
BRIEF DESCRIPTION Swiss physician and experimental immunologist
DATE OF BIRTH January 6, 1944
PLACE OF BIRTH Riehen , Basel-Stadt