Frana became a professional tennis player in 1986 and was in the final of an ATP tournament for the first time the following year in Barcelona with Christian Miniussi . In 1988 he won his first double title on the ATP Tour, again alongside Miniussi. In total, he came to seven double titles in the course of his career, another nine times he was in the finals of a double competition. In 1991 he won his first of three individual titles on the ATP World Tour in Guarujá . He reached his highest scores in the world rankings in 1995 with position 30 in singles and in 1992 with position 14 in doubles.
Frana played 17 singles and 20 doubles games between 1986 and 1997 for the Argentine Davis Cup team . At the quarter-finals against Germany in 1990 , he won the doubles against Eric Jelen and Michael Stich alongside Gustavo Luza and thus contributed significantly to Argentina’s 3-2 victory. When the two countries met again the following year, he lost both singles against Stich and Boris Becker and the doubles alongside Christian Miniussi, giving Germany a 5-0 revenge.