Regeneron Pharmaceuticals
Regeneron Pharmaceuticals
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legal form | Incorporated |
ISIN | US75886F1075 |
founding | 1988 |
Seat | Tarrytown , United States |
management | Leonard S. Schleifer, President & CEO |
Number of employees | 8,100 |
sales | 5,872,000,000 USD |
Branch | pharmacy |
Website | www.regeneron.com |
As of December 31, 2019 |
The biotechnology company Regeneron Pharmaceuticals was founded in 1988 and is traded on the NASDAQ stock exchange under the symbol "REGN". Regeneron Pharmaceuticals is a global leader in the manufacture of monoclonal antibodies , some of which Regeneron markets itself, but some of which are also sold under license or in cooperation with other companies, such as Bayer or Sanofi .
Products
Regeneron Pharmaceuticals is a leader in human antibody production and has a significant pipeline of experimental candidates for the treatment of cancer, rheumatoid arthritis and hypercholesterolemia , for example . The strategic cooperation with Sanofi enables the company to make a long-term forecast of the financing.
Rilonacept (tradename Arcalyst) is an interleukin-1 inhibitor ; H. an anti-inflammatory medicine used to treat the rare hereditary disorder cryopyrin-associated periodic syndrome (CAPS). It was Regeneron's first drug and was approved by the Food and Drug Administration (FDA) in the US in 2008 .
Aflibercept is a recombinant growth factor inhibitor that - under the trade name Eylea - is used to treat age-related macular degeneration (AMD) . In Germany, Eylea is marketed by Bayer Healthcare Pharmaceuticals. Under the trade name Zaltrap, the same substance is used for the treatment of metastatic colorectal cancer. (mCRC) . Eylea is the company's main product.
pipeline
- Alirocumab (REGN727): proprotein convertase subtilisin / kexin type 9 antibody for lowering LDL cholesterol in familial hypercholesterolemia
- Sarilumab (REGN88): IL-6R antibody used to treat rheumatoid arthritis
literature
- How Two Guys From Queens Are Changing Drug Discovery , FORBES August 14, 2013, accessed March 30, 2014
Individual evidence
- ^ Regeneron Pharmaceuticals: Investor FAQs . 2014. Retrieved March 30, 2014.
- ^ Regeneron Pharmaceuticals: Company - Management . 2014. Retrieved March 30, 2014.
- ↑ About Regeneron Pharmaceuticals: Innovative Biotechnology. In: Company information. 2020, accessed on February 12, 2020 .
- ↑ a b Regeneron: 2017 Form 10-K Report. (PDF) Retrieved March 17, 2018 (English).
- ↑ a b c Regeneron Pharmaceuticals: Pipeline . 2014. Retrieved March 30, 2014.
- ^ Regeneron Pharmaceuticals: Company . 2014. Retrieved March 30, 2014.
- ↑ www.regeneron.com/ARCALYST , Rilonacept on the manufacturer's website (English), accessed on March 30, 2014.
- ↑ New medicines Eylea (Aflibercept) (PDF; 132 kB) Information from the Medicines Commission of the German Medical Association (AkdÄ), as of February 28, 2013
- ↑ New on the market: Aflibercept in Macular Degeneration DAZ from January 16, 2013, accessed on March 30, 2013.
- ↑ New drugs Zaltrap (Aflibercept) (PDF; 852 kB) Information from the drug commission of the German medical profession (AkdÄ), as of May 22, 2013.