Butalbital

Butalbital

Clinical data
Pregnancy category	?
Routes of administration	?
Legal status
Legal status	US: Schedule III
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Elimination half-life	about 35 hours
Excretion	?
Identifiers
IUPAC name 5-(2-methylpropyl)-5-(2-propenyl)- 2,4,6(1H,3H,5H)-pyrimidinetrione
CAS Number	77-26-9
PubChem CID	2481
DrugBank	APRD00266
CompTox Dashboard (EPA)	DTXSID6022711
ECHA InfoCard	100.000.926
Chemical and physical data
Formula	C11H16N2O3
Molar mass	224.256 g·mol−1

Butalbital, 5-allyl-5-isobutylbarbituric acid, is a barbiturate with an intermediate duration of action. It has the same chemical formula as talbutal but a different structure. Butalbital is often combined with other medications, such as acetaminophen or aspirin, and is commonly prescribed for the treatment of pain and headache. The various formulations combined with codeine are FDA approved for the treatment of tension headaches.

Combinations include:

• butalbital and acetaminophen (Axocet®, Bucet®, Bupap®, Cephadyn®, Dolgic®, Phrenilin®, Phrenilin Forte®, Sedapap®)
• butalbital, acetaminophen, and caffeine (Fioricet®, Esgic®, Esgic-Plus®)
• butalbital and aspirin (Axotal®)
• butalbital, aspirin, and caffeine (Fiorinal®, Fiormor®, Fiortal®, Fortabs®, Laniroif®)
• butalbital, acetaminophen, caffeine, and codeine phosphate (Fioricet #3 with Codeine®) (Fioricet w/ Codeine®)
• butalbital, aspirin, caffeine, and codeine phosphate (Fiorinal #3 with Codeine®) (Fiorinal w/ Codeine®)

Fioricet (50/40/325)

Side effects

Side effects for any drug are difficult to predict, but commonly reported side effects for Butalbital include:

• Dizziness
• Drowsiness
• Intoxicated feeling
• Light-headedness
• Nausea
• Sedation
• Addiction
• Severe impairment of judgement

There are other potential side effects, this list should not be considered all-inclusive.

Dangers and Risks

Butalbital is a physically and psychologically addictive barbiturate. Butalbital should not be mixed with alcohol due to increased risk of intoxication.

There are other potential risks; this list should not be considered all-inclusive.

External links

"Butalbital". On-line Medical Dictionary. Retrieved June 26. {{cite web}}: Check date values in: |accessdate= (help); Unknown parameter |accessyear= ignored (|access-date= suggested) (help)

"Butalbital and Acetaminophen (Systemic)". MedicinePlus Drug Information. Retrieved December 31. {{cite web}}: Check date values in: |accessdate= (help); Unknown parameter |accessyear= ignored (|access-date= suggested) (help)

"Controlled Substances in Schedule III". Drug Enforcement Agency. 2007. Retrieved 2007-01-13.