Axel Haverich

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Axel Haverich (2007)

Axel Have Rich (* 9. March 1953 in Lemgo ) is a German transplant - physicians and cardiac surgeon .

Life

Axel Haverich attended elementary school in Humfeld from 1959 to 1963 and then the grammar school in Barntrup . After graduating from high school in 1972, he was doing civilian service with the Red Cross before studying medicine at the Hannover Medical School (MHH). At the end of 1978 he received his license to practice medicine and a year later he received his doctorate . The phase as an assistant doctor at the Center for Surgery at the university ended in 1985. During this time, Axel Haverich was employed as a research assistant at the Department of Cardiovascular Surgery at Stanford University in 1983, on a grant from the German Research Foundation . In 1985 he became senior physician at the Clinic for Thoracic, Cardiac and Vascular Surgery at the Hannover Medical School. Two years later he completed his habilitation .

In 1992 he was appointed adjunct professor . From 1993 to 1996 he was director of the department for cardiovascular surgery at the University of Kiel. He returned to the MHH in 1996 as director of the Clinic for Cardiac, Thoracic, Transplant and Vascular Surgery. In 1995 he received the Leibniz Prize for German Scientists from the German Research Foundation (DFG). With this award he founded the Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO) in 1996 . There he and his team developed a heart valve that grew with the child.

plant

He conducts research in heart and lung surgery, transplant medicine (lung transplants, tissue regeneration) and, in this context, on alternatives to the scarce human donor organs, for example via renewable organs (tissue engineering, tissue cultivation), implantable animal organs (genetically modified pigs), organs from 3D -Printers or artificial organs (biohybrid lungs, with the patient's own cells grown), as well as induced pluripotent stem cells for use in tissue regeneration. In 2002 he transplanted heart valves that grew with the child for the first time, in which organ donor heart valves were enriched with cells from the patient. These first attempts on children outside of Germany were ethically controversial. The commission had to withdraw the nomination for the future prize for this work due to patent disputes. He developed an Organ Care System (OCS) to keep lungs alive outside the body, for example to bridge longer periods during transplants or with the aim of treating the lungs of patients outside the body (for example radiation for cancer therapy) .

In 2017 he presented a new thesis on the development of arteriosclerosis . According to this, the cause is not in the inner wall of the blood vessels, but in their own fine channels (microvessels, vasa vasorum) for blood supply in their outer wall, which are clogged by inflammation due to infections or fine dust. The plaques are then the result of dead cells in the vessel wall. As a surgeon, he noticed that patients with high-grade arteriosclerosis also had healthy vascular segments. These were those whose walls were thinner than 0.5 mm and who therefore did not need a vasa vasorum (VV) for blood supply. In addition, these were stabilized and moved by muscles. If the VV is blocked by dead cells and fat particles in the event of inflammation, further cells in the vessel wall die and, according to Haverich, plaques form. According to Haverich, this agrees with epidemiological observations that heart attacks increased after flu epidemics and particulate matter pollution.

Memberships

Haverich is or was a member of numerous commissions and societies. These include a. the German Society for Thoracic, Cardiac and Vascular Surgery (board member 1991 to 1995), the Commission for Animal Research of the German Research Foundation (since 1999), the Commission for Stem Cell Research of the German Medical Association (since 2000), the Senate of the German Research Foundation (2001 to 2007), the German Academy of Sciences Leopoldina (since 2003) and the Senate of the MHH (1999 to 2003).

Editorial activity

Awards

literature

Web links

Individual evidence

  1. Bettina Zinter: Axel Haverich , in Tigo Zeyen, Anne Weber-Ploemacher (ed.), Joachim Giesel (photos): 100 hannoversche Köpfe , Hameln: CW Niemeyer Buchverlage, 2006, ISBN 978-3-8271-9251-6 and ISBN 3-8271-9251-X , pp. 76f.
  2. a b Georg Thieme Verlag KG, press conference on the occasion of the 124th Congress of the German Society for Surgery Tuesday, May 1, 2007, 2 p.m. to 3 p.m.  ( page no longer available , search in web archivesInfo: The link was automatically marked as defective. Please check the link according to the instructions and then remove this notice. , accessed October 15, 2008.@1@ 2Template: Dead Link / www.thieme.de  
  3. Hannover Medical School, German Future Prize 2008 , October 15, 2008.
  4. Deutschlandfunk: 20 Years of the German Future Prize - In the Thicket of Visions , November 27, 2016, accessed on January 2, 2017
  5. - Denominated heart valves. Retrieved on May 7, 2019 (German).
  6. Jump up ↑ Infekt und Infarkt , Die Zeit from May 9, 1997, accessed on January 18, 2017
  7. Focus Gesundheit, January 17, 2017
  8. MHH press release , January 17, 2017
  9. Haverich: A Surgeon's View on the Pathogenesis of Atherosclerosis, Circulation, Volume 135, 2017, Issue 3
  10. Member entry of Axel Haverich (with picture) at the German Academy of Natural Scientists Leopoldina , accessed on July 12, 2016.
  11. Axel Haverich on the website of the Hannover Medical School. Retrieved October 15, 2008.
  12. Juliane Kaune: A ring of friendship , in: Hannoversche Allgemeine Zeitung of October 25, 2007, p. 19.