Edwin G. Krebs
Edwin Gerhard Krebs (born June 6, 1918 in Lansing , Iowa , † December 21, 2009 in Seattle , Washington ) was an American biochemist and Nobel Prize winner .
Life
Krebs studied biology and chemistry at the University of Illinois since 1936 with a bachelor's degree in 1940 and then medicine at Washington University in St. Louis , where he received his doctorate in medicine in 1943 (MD). In 1944/45 he trained as a resident at Barnes Hospital in St. Louis and from 1946 he was a Research Fellow of the National Institutes of Health at the University of Washington in Seattle, where he became Assistant Professor and later Professor of Biochemistry in 1948. 1968 to 1976 he was Professor of Biochemistry at the University of California, Davis , and then again until his retirement in 1988 Professor of Pharmacology at the University of Washington (Medical College). From 1980 to 1990 he was a senior investigator at the Howard Hughes Medical Institute .
He had been married since 1945 and had three children.
With Edmond H. Fischer , who came from Geneva as a post-doctoral student and became a professor in Seattle in 1953, Krebs clarified the mechanism of phosphorylation of proteins (enzymes), which plays a central role in metabolism and controls the activity of many enzymes.
Honors
In 1971, Krebs was elected to the American Academy of Arts and Sciences , and he was a member of the National Academy of Sciences since 1973 . In 1978 he received a Gairdner Foundation International Award , in 1989 the Albert Lasker Award for Basic Medical Research and the Louisa Gross Horwitz Prize . In 1992, together with Edmond H. Fischer, he was awarded the Nobel Prize in Physiology or Medicine "for their discovery of the mechanisms that control the metabolic processes in organisms".
He received honorary doctorates from the University of Geneva (1979), the Medical College of Ohio and Indiana University. In 1959 and 1966 he was a Guggenheim Fellow.
literature
- Edwin G. Krebs , in: Internationales Biographisches Archiv 01/1993 of December 28, 1992, in the Munzinger Archive ( beginning of article freely available)
- Gisela Baumgart: Krebs, Edwin Gerhard. In: Werner E. Gerabek , Bernhard D. Haage, Gundolf Keil , Wolfgang Wegner (eds.): Enzyklopädie Medizingeschichte. De Gruyter, Berlin / New York 2005, ISBN 3-11-015714-4 , p. 805.
Web links
- Information from the Nobel Foundation on the 1992 award to Edwin G. Krebs (English)
Individual evidence
- ↑ Birth and career data according to American Men and Women of Science , Thomson Gale 2004
| personal data | |
|---|---|
| SURNAME | Krebs, Edwin G. |
| ALTERNATIVE NAMES | Krebs, Edwin Gerhard (full name) |
| BRIEF DESCRIPTION | American biochemist |
| DATE OF BIRTH | June 6, 1918 |
| PLACE OF BIRTH | Lansing , Iowa |
| DATE OF DEATH | December 21, 2009 |
| Place of death | Seattle , Washington |