Fritz Albert Lipmann

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Fritz Lipmann

Fritz Albert Lipmann (born June 12, 1899 in Königsberg i. Pr .; † July 24, 1986 in Poughkeepsie , New York ) was a German-American biochemist and Nobel Prize winner.

Life

Lipmann attended the Collegium Fridericianum . He first studied medicine, later chemistry and pharmacology at the Albertus University in Königsberg , the Ludwig Maximilians University in Munich and the Friedrich Wilhelms University in Berlin . In 1924 he was promoted to Dr. med. PhD . In 1928 the doctorate to Dr. phil. As early as 1927 he became an employee of Otto Meyerhof at the Kaiser Wilhelm Institute for Cell Physiology in Berlin-Dahlem , and in 1929 in Heidelberg . 1930/31 worked in Albert Fischer's laboratory at the Kaiser Wilhelm Institute for Biology in Berlin , he then went to New York City as a Rockefeller Fellow , followed in 1932 by Albert Fischer to the Carlsberg Laboratory in Copenhagen , where he studied the role of glucose in the embryo Researched cell metabolism, emigrated to the USA in 1939 and was naturalized there in 1944. Lipmann initially taught at Cornell University School of Medicine in New York and headed the biochemical research laboratory at Massachusetts General Hospital in Boston from 1941 to 1957 . In 1941 he became a lecturer, in 1943 associate professor and in 1949 full professor of biochemistry at Harvard Medical School and from 1957 to 1969 at Rockefeller University in New York City.

Lipmann dealt with B vitamins and enzymes and discovered coenzyme A in 1947 , due to the existence of which a new type of metabolism was developed. In 1953, together with James Baddiley , he described the structure of coenzyme A. In 1969 he was accepted into the German Academy of Natural Scientists Leopoldina . Lipmann discovered that ATP is the main energy carrier in the cell, which he wrote about in his specialist publication entitled Metabolic Generation and Utilization of Phosphate Bond Energy (1941). His autobiography Wanderings of a Biochemist was published in 1971.

Since 1931 Lipmann was married to the fashion illustrator Elfriede “Freda” Hall (1906–2008).

Honors

Fritz Lipmann's son is amazed at his father's Nobel Prize for Medicine (1953)

In 1949 Lipmann was elected to the American Academy of Arts and Sciences , 1950 to the National Academy of Sciences and 1959 to the American Philosophical Society . In 1953 he and Hans Adolf Krebs received the Nobel Prize for Medicine . In 1969 he became an honorary member of the Leopoldina.

The Leibniz Institute for Aging Research in Jena has been named after him since 2005 .

literature

Web links

Commons : Fritz Lipmann  - Collection of images, videos and audio files

Individual evidence

  1. Medical dissertation: About the effect of the shift in the hydrogen ion concentration, mainly due to the hydrolysis of the salts, on the flocculation phenomenon on the positive and negative iron hydroxide sol .
  2. Philosophical dissertation: Experiments on the mechanism of the effect of fluoride .
  3. Today the building houses the archive of the Max Planck Society .
  4. ^ Renate Wagner: Lipmann, Fritz Albert. In: Werner E. Gerabek , Bernhard D. Haage, Gundolf Keil , Wolfgang Wegner (eds.): Enzyklopädie Medizingeschichte. De Gruyter, Berlin / New York 2005, ISBN 3-11-015714-4 , p. 856.
  5. Member entry of Fritz Lipmann (with picture and CV) at the German Academy of Natural Scientists Leopoldina , accessed on September 21, 2016.
  6. ^ History of the ATP on the Nobel Prize website
  7. ^ Metabolic Generation and Utilization of Phosphate Bond Energy. In: Advances in Enzymology and Related Areas of Molecular Biology. Volume 1, pp. 99-162, 1941, doi: 10.1002 / 9780470122464.ch4
  8. Deaths: Lipmann, Freda Hall (New York Times, May 11, 2008)