Venkatraman Ramakrishnan

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Venkatraman Ramakrishnan (2015)

Venkatraman "Venki" Ramakrishnan (* 1952 in Chidambaram , Tamil Nadu ) is an Indian-British-American ribosome researcher and structural biologist. In 2009 he received the Nobel Prize in Chemistry and has been President of the Royal Society since December 1, 2015 .

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Ramakrishnan received his Bachelor of Science degree in physics from the University of Baroda in India in 1971 . In 1976 he was at the Ohio University in Physics Ph. D. doctorate . He then studied biology at the University of California, San Diego until 1978 . As a post-doctoral student, he worked in the chemistry department of Yale University from 1978 to 1982 . In 1982 and 1983 he conducted research at Oak Ridge National Laboratory and from 1983 to 1995 in the biology department of Brookhaven National Laboratory . From 1995 to 1999 he was a professor in the Biochemistry Department at the University of Utah . Since 1999 he has been doing research at the Laboratory for Molecular Biology of the Medical Research Council in Cambridge , England , which he already knew from a stay as a visiting scientist in 1991 and 1992. Ramakrishnan is a Fellow of Trinity College at Cambridge University.

Among other things, his research has contributed to the mechanistic understanding of the synthesis of proteins by the ribosome (the so-called translation ) in the context of gene expression . In 2000 he and his group determined the X-ray crystal structure of the 30S subunit of the ribosome, as well as of complexes of this subunit with various antibiotics . Subsequent work was concerned with the mechanism underlying the accuracy of protein synthesis. In 2006, he clarified the atomic structure of the entire ribosome in complex with his research group tRNA - and mRNA - ligands on. In addition to his research on the ribosome, Ramakrishnan is also known for his previous research on the structure of histones and chromatin . He has been a member of the European Molecular Biology Organization since 2002, of the Royal Society (EMBO) since 2003 and of the US National Academy of Sciences since 2004 . Together with Thomas A. Steitz and Ada Yonath, he was awarded the Nobel Prize in Chemistry 2009 “for studies on the structure and function of the ribosome”.

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Web links

Commons : Venkatraman Ramakrishnan  - collection of pictures, videos and audio files

Individual evidence

  1. ↑ V. Ramakrishnan (2008): What we have learned from ribosome structures. In: Biochem. Soc. Trans. Volume 36, Part 4, pp. 567-574. PMID 18631119 doi : 10.1042 / BST0360567
  2. ↑ BT Wimberly, DE Brodersen, WM Clemons Jr, RJ Morgan-Warren, AP Carter, C. Vonrhein, T. Hartsch, V. Ramakrishnan (2000): Structure of the 30S ribosomal subunit. In: Nature. Vol. 407, No. 6802, pp. 327-339. PMID 11014182 doi : 10.1038 / 35030006
  3. ^ AP Carter, WM Clemons Jr., DE Brodersen, BT Wimberly, RJ Morgan-Warren, V. Ramakrishnan (2000): Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics. In: Nature. Vol. 407, No. 6802, pp. 340-348. PMID 11014183 doi : 10.1038 / 35030019
  4. ↑ Information from the Nobel Foundation on the 2009 award ceremony to Venkatraman Ramakrishnan, Thomas A. Steitz and Ada E. Yonath (English)
  5. ↑ Member entry of Ph.D. Venkatraman Ramakrishnan (with picture and CV) at the German Academy of Natural Scientists Leopoldina , accessed on July 19, 2016.
personal data
SURNAME Ramakrishnan, Venkatraman
ALTERNATIVE NAMES Ramakrishnan, Venki (nickname)
BRIEF DESCRIPTION American structural biologist
DATE OF BIRTH 1952
PLACE OF BIRTH Chidambaram , Tamil Nadu