Jeffrey C. Hall

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Jeffrey C. Hall

Jeffrey Connor Hall (born May 3, 1945 in Brooklyn , New York City ) is an American geneticist and chronobiologist and professor emeritus of Brandeis University in Waltham , Massachusetts and the University of Maine near Bangor , Maine . Hall was awarded the Nobel Prize in Physiology or Medicine in 2017 together with Michael Rosbash and Michael W. Young .

Life

Hall grew up as the son of a journalist in the area of Washington, DC in Maryland on. From 1963 he studied, first at Amherst College in Amherst , then at the University of Washington in Seattle , Washington , where he received a bachelor's degree in 1969 and a Ph.D. in 1971. in genetics . As a postdoctoral fellow , he worked with Seymour Benzer at the California Institute of Technology (Caltech) in Pasadena , California .

Hall was a faculty member at Brandeis University in Waltham , Massachusetts from 1974 (Assistant Professor) to 2008 . From 2007 until his retirement in 2009, he held a position as professor of biology at the University of Maine near Bangor , Maine . Hall also studies the history of the American Civil War , particularly the Battle of Gettysburg, at an academic level .

Act

Hall is considered a pioneer in behavioral genetics and its neurobiological basis in the fruit fly ( Drosophila melanogaster ). His neurogenetic investigations contributed significantly to the understanding of the molecular mechanisms of sex differentiation in the nervous system and biological clocks .

Together with Michael Rosbash Hall was in 1984 the first time period , a " Verhaltensgen the" circadian rhythm clone . Her work subsequently led to the identification and functional analysis of the proteins that underlie the biological clock of the fruit fly ( Drosophila melanogaster ). Hall and Rosbash proposed a negative feedback of transcription before and mechanism of biological clock. The model is still valid and could be applied to all living beings, including humans. The Chronotherapy considered as potential application of research results in people with insomnia . Hall's studies of the fruitless gene, including its cloning, yielded important insights into the sex development of the fruit flies.

Awards

literature

Web links

Individual evidence

  1. Livestream via nobelprize.org (accessed on October 2, 2017).
  2. ^ Hall, JC (2003) The Stand of the US Army at Gettysburg (Indiana Univ. Press, Bloomington) ISBN 978-0-253-34258-4
  3. Book of Members 1780 – present (PDF, 1039 kB) of the American Academy of Arts and Sciences (amacad.org); Retrieved October 2, 2011
  4. ^ RJ Greenspan: The 2003 Genetics Society of America Medal; Jeffrey C. Hall. In: Genetics. Volume 164, Number 4, August 2003, pp. 1245-1247, PMID 15106661 , PMC 1462664 (free full text).
  5. 2009 Gruber Neuroscience Prize , Laureate Profile and Jeffrey Hall at gruberprizes.org; Retrieved October 2, 2011
  6. ^ Louisa Gross Horwitz Prize - 2011 at Columbia University (columbia.edu); Retrieved October 2, 2011
  7. Jeffrey C. Hall at the Gairdner Foundation (gairdner.org); Retrieved August 7, 2012