'''25N-NBOMe''' ('''2C-N-NBOMe''', '''NBOMe-2C-N''') is a [[derivative (chemistry)|derivative]] of the [[hallucinogen]] [[2C-N]]. The pharmacological properties of 25N-NBOMe have not been described in the scientific literature, but it is believed to act in a similar manner to related compounds such as [[25I-NBOMe]] and [[25C-NBOMe]], which are potent [[agonist]]s at the [[5HT2A receptor|5HT<sub>2A</sub>]] [[Receptor (biochemistry)|receptor]].<ref>{{Cite journal | last1 = Hansen | first1 = M. | last2 = Phonekeo | first2 = K. | last3 = Paine | first3 = J. S. | last4 = Leth-Petersen | first4 = S. | last5 = Begtrup | first5 = M. | last6 = Bräuner-Osborne | first6 = H. | last7 = Kristensen | first7 = J. L. | doi = 10.1021/cn400216u | title = Synthesis and Structure-Activity Relationships of N-Benzyl Phenethylamines as 5-HT<sub>2A/2C</sub> Agonists | journal = ACS Chemical Neuroscience | volume = 5 | issue = 3 | pages = 243–9 | year = 2014 | pmid = 24397362| pmc = 3963123
'''25N-NBOMe''' ('''2C-N-NBOMe''', '''NBOMe-2C-N''') is a [[derivative (chemistry)|derivative]] of the [[hallucinogen]] [[2C-N]]. The pharmacological properties of 25N-NBOMe have not been described in the scientific literature, but it is believed to act in a similar manner to related compounds such as [[25I-NBOMe]] and [[25C-NBOMe]], which are potent [[agonist]]s at the [[5HT2A receptor|5HT<sub>2A</sub>]] [[Receptor (biochemistry)|receptor]].<ref>{{Cite journal | last1 = Hansen | first1 = M. | last2 = Phonekeo | first2 = K. | last3 = Paine | first3 = J. S. | last4 = Leth-Petersen | first4 = S. | last5 = Begtrup | first5 = M. | last6 = Bräuner-Osborne | first6 = H. | last7 = Kristensen | first7 = J. L. | doi = 10.1021/cn400216u | title = Synthesis and Structure-Activity Relationships of N-Benzyl Phenethylamines as 5-HT<sub>2A/2C</sub> Agonists | journal = ACS Chemical Neuroscience | volume = 5 | issue = 3 | pages = 243–9 | year = 2014 | pmid = 24397362| pmc = 3963123
}}</ref><ref>{{cite thesis | vauthors = Hansen M | title = Design and Synthesis of Selective Serotonin Receptor Agonists for Positron Emission Tomography Imaging of the Brain. | degree = Ph.D. | publisher = University of Copenhagen | date = 2010-12-16 | doi = 10.13140/RG.2.2.33671.14245}}</ref> 25N-NBOMe has been sold as a street drug and has only been described in the literature in terms of identification by forensic analysis.<ref>{{cite journal|last=Casale|first=John F.|author2=Hays, Patrick A.|title=Characterization of Eleven 2,5-Dimethoxy-N-(2-methoxybenzyl)phenethylamine (NBOMe) Derivatives and Differentiation from their 3- and 4-Methoxybenzyl Analogues - Part I|journal=Microgram Journal|year=2012|volume=9|issue=2|pages=84–109|url=https://www.justice.gov/dea/pr/microgram-journals/2012/mj9_84-109.pdf|access-date=14 January 2014}}</ref><ref>{{cite journal | title=Two new synthetic cannabinoids, AM-2201 benzimidazole analog (FUBIMINA) and (4-methylpiperazin-1-yl)(1-pentyl-1H-indol-3-yl)methanone (MEPIRAPIM), and three phenethylamine derivatives, 25H-NBOMe 3,4,5-trimethoxybenzyl analog, 25B-NBOMe, and 2C-N-NBOMe, identified in illegal products |vauthors=Uchiyama N, Shimokawa Y, Matsuda S, Kawamura M, Kikura-Hanajiri R, Goda Y | journal=Forensic Toxicology | year=2014 | volume=32 | issue=1 | pages=105–115 | doi=10.1007/s11419-013-0217-2|s2cid=32599561 }}</ref>
}}</ref><ref>{{cite thesis | vauthors = Hansen M | title = Design and Synthesis of Selective Serotonin Receptor Agonists for Positron Emission Tomography Imaging of the Brain. | degree = Ph.D. | publisher = University of Copenhagen | date = 2010-12-16 | doi = 10.13140/RG.2.2.33671.14245}}</ref> 25N-NBOMe has been sold as a street drug and has only been described in the literature in terms of identification by forensic analysis.<ref>{{cite journal|last=Casale|first=John F.|author2=Hays, Patrick A.|title=Characterization of Eleven 2,5-Dimethoxy-N-(2-methoxybenzyl)phenethylamine (NBOMe) Derivatives and Differentiation from their 3- and 4-Methoxybenzyl Analogues - Part I|journal=Microgram Journal|year=2012|volume=9|issue=2|pages=84–109|url=https://www.justice.gov/dea/pr/microgram-journals/2012/mj9_84-109.pdf|access-date=14 January 2014}}</ref><ref>{{cite journal | title=Two new synthetic cannabinoids, AM-2201 benzimidazole analog (FUBIMINA) and (4-methylpiperazin-1-yl)(1-pentyl-1H-indol-3-yl)methanone (MEPIRAPIM), and three phenethylamine derivatives, 25H-NBOMe 3,4,5-trimethoxybenzyl analog, 25B-NBOMe, and 2C-N-NBOMe, identified in illegal products |vauthors=Uchiyama N, Shimokawa Y, Matsuda S, Kawamura M, Kikura-Hanajiri R, Goda Y | journal=Forensic Toxicology | year=2014 | volume=32 | issue=1 | pages=105–115 | doi=10.1007/s11419-013-0217-2|s2cid=32599561 }}</ref>
25N-NBOMe is illegal in Alabama,<ref>[https://legiscan.com/AL/text/SB333/id/988417/Alabama-2014-SB333-Enrolled.pdf Alabama Senate Bill SB 333: Controlled Substances]</ref> and Hungary.<ref>[http://www.daath.hu/incoming/designer_jogi_lista_20150903_BSZKI_Daath_kieg.pdf A Daath.hu kiegészítése a BSZKI "designer jogi listáján" nem szereplő, de az UP jegyzék 1.-4. szerkezeti leírásainak megfelelő, illetve az 5. felsorolásában szereplő néhány anyagról]</ref>
25N-NBOMe is illegal in Alabama.<ref>[https://legiscan.com/AL/text/SB333/id/988417/Alabama-2014-SB333-Enrolled.pdf Alabama Senate Bill SB 333: Controlled Substances]</ref>
25N-NBOMe is illegal in Hungary.<ref>[http://www.daath.hu/incoming/designer_jogi_lista_20150903_BSZKI_Daath_kieg.pdf A Daath.hu kiegészítése a BSZKI "designer jogi listáján" nem szereplő, de az UP jegyzék 1.-4. szerkezeti leírásainak megfelelő, illetve az 5. felsorolásában szereplő néhány anyagról]</ref>
25N-NBOMe (2C-N-NBOMe, NBOMe-2C-N) is a derivative of the hallucinogen2C-N. The pharmacological properties of 25N-NBOMe have not been described in the scientific literature, but it is believed to act in a similar manner to related compounds such as 25I-NBOMe and 25C-NBOMe, which are potent agonists at the 5HT2Areceptor.[1][2] 25N-NBOMe has been sold as a street drug and has only been described in the literature in terms of identification by forensic analysis.[3][4]
The Riksdag added 25N-NBOMe to Narcotic Drugs Punishments Act under swedish schedule I ("substances, plant materials and fungi which normally do not have medical use") as of January 16, 2015, published by Medical Products Agency (MPA) in regulation LVFS 2014:11 listed as 25N-NBOMe, and 2-(2,5-dimetoxi-4-nitrofenyl)-N-(2-metoxibensyl)etanamin.[7]
^Hansen M (2010-12-16). Design and Synthesis of Selective Serotonin Receptor Agonists for Positron Emission Tomography Imaging of the Brain (Ph.D. thesis). University of Copenhagen. doi:10.13140/RG.2.2.33671.14245.
^Uchiyama N, Shimokawa Y, Matsuda S, Kawamura M, Kikura-Hanajiri R, Goda Y (2014). "Two new synthetic cannabinoids, AM-2201 benzimidazole analog (FUBIMINA) and (4-methylpiperazin-1-yl)(1-pentyl-1H-indol-3-yl)methanone (MEPIRAPIM), and three phenethylamine derivatives, 25H-NBOMe 3,4,5-trimethoxybenzyl analog, 25B-NBOMe, and 2C-N-NBOMe, identified in illegal products". Forensic Toxicology. 32 (1): 105–115. doi:10.1007/s11419-013-0217-2. S2CID32599561.