Choline transporter-like protein 1: Difference between revisions

SLC44A1
Identifiers
Aliases	SLC44A1, CD92, CDW92, CHTL1, CTL1, solute carrier family 44 member 1, CONATOC
External IDs	OMIM: 606105 MGI: 2140592 HomoloGene: 11137 GeneCards: SLC44A1
Gene location (Human)
Chr.	Chromosome 9 (human)
End	105,439,171 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	53,622,478 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; inferior ganglion of vagus nerve; ; internal globus pallidus; ; subthalamic nucleus; ; superior vestibular nucleus; ; external globus pallidus; ; ventral tegmental area; ; corpus epididymis; ; corpus callosum; ; pons;
	Top expressed in
	hair follicle; ; left colon; ; urothelium; ; pyloric antrum; ; medullary collecting duct; ; gastric mucosa; ; mucous cell of stomach; ; Paneth cell; ; ileum; ; crypt of lieberkuhn of small intestine;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	choline transmembrane transporter activity;
Cellular component	extracellular exosome; nucleoplasm; mitochondrion; plasma membrane; integral component of membrane; mitochondrial outer membrane; membrane;
Biological process	phosphatidylcholine biosynthetic process; transmembrane transport; choline transport; choline catabolic process; transport;
	Sources:Amigo / QuickGO
Orthologs
	23446
	100434
	ENSG00000070214
	ENSMUSG00000028412
	Q8WWI5
	Q6X893
	NM_001286730; NM_022109; NM_080546; NM_001330731
	NM_001159633; NM_133891; NM_001374697
	NP_001273659; NP_001317660; NP_536856
	NP_001153105; NP_598652; NP_001361626
	Wikidata
View/Edit Human	View/Edit Mouse

Browse history interactively

← Previous edit Next edit →

Content deleted Content added

VisualWikitext

Inline

Revision as of 06:29, 10 June 2016

Choline transporter-like protein 1 is a protein that in humans is encoded by the SLC44A1 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000070214 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028412 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wille S, Szekeres A, Majdic O, Prager E, Staffler G, Stöckl J, Kunthalert D, Prieschl EE, Baumruker T, Burtscher H, Zlabinger GJ, Knapp W, Stockinger H (November 2001). "Characterization of CDw92 as a member of the choline transporter-like protein family regulated specifically on dendritic cells". Journal of Immunology. 167 (10): 5795–804. doi:10.4049/jimmunol.167.10.5795. PMID 11698453.
^ O'Regan S, Traiffort E, Ruat M, Cha N, Compaore D, Meunier FM (February 2000). "An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins". Proceedings of the National Academy of Sciences of the United States of America. 97 (4): 1835–40. doi:10.1073/pnas.030339697. PMC 26522. PMID 10677542.
^ "Entrez Gene: SLC44A1 solute carrier family 44, member 1".

External links

SLC44A1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This membrane protein–related article is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000070214 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028412 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11698453-5] Wille S, Szekeres A, Majdic O, Prager E, Staffler G, Stöckl J, Kunthalert D, Prieschl EE, Baumruker T, Burtscher H, Zlabinger GJ, Knapp W, Stockinger H (November 2001). "Characterization of CDw92 as a member of the choline transporter-like protein family regulated specifically on dendritic cells". Journal of Immunology. 167 (10): 5795–804. doi:10.4049/jimmunol.167.10.5795. PMID 11698453.

[pmid10677542-6] O'Regan S, Traiffort E, Ruat M, Cha N, Compaore D, Meunier FM (February 2000). "An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins". Proceedings of the National Academy of Sciences of the United States of America. 97 (4): 1835–40. doi:10.1073/pnas.030339697. PMC 26522. PMID 10677542.

[entrez-7] "Entrez Gene: SLC44A1 solute carrier family 44, member 1".

[1]

[2]

[3]

[4]

[5]

[6]

[7]

@@ Line 1: / Line 1: @@
 {{Infobox_gene}}
-'''Choline transporter-like protein 1''' is a [[protein]] that in humans is encoded by the ''SLC44A1'' [[gene]].<ref name="pmid11698453">{{cite journal |author1=Wille S |author2=Szekeres A |author3=Majdic O |author4=Prager E |author5=Staffler G |author6=Stockl J |author7=Kunthalert D |author8=Prieschl EE |author9=Baumruker T |author10=Burtscher H |author11=Zlabinger GJ |author12=Knapp W |author13=Stockinger H | title = Characterization of CDw92 as a member of the choline transporter-like protein family regulated specifically on dendritic cells | journal = J Immunol | volume = 167 | issue = 10 | pages = 5795–804 |date=Nov 2001 | pmid = 11698453 | pmc =  | doi =  10.4049/jimmunol.167.10.5795}}</ref><ref name="pmid10677542">{{cite journal |author1=O'Regan S |author2=Traiffort E |author3=Ruat M |author4=Cha N |author5=Compaore D |author6=Meunier FM | title = An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins | journal = Proc Natl Acad Sci U S A | volume = 97 | issue = 4 | pages = 1835–40 |date=Mar 2000 | pmid = 10677542 | pmc = 26522 | doi = 10.1073/pnas.030339697 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SLC44A1 solute carrier family 44, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23446| accessdate = }}</ref>
+'''Choline transporter-like protein 1''' is a [[protein]] that in humans is encoded by the ''SLC44A1'' [[gene]].<ref name="pmid11698453">{{cite journal | vauthors = Wille S, Szekeres A, Majdic O, Prager E, Staffler G, Stöckl J, Kunthalert D, Prieschl EE, Baumruker T, Burtscher H, Zlabinger GJ, Knapp W, Stockinger H | title = Characterization of CDw92 as a member of the choline transporter-like protein family regulated specifically on dendritic cells | journal = Journal of Immunology | volume = 167 | issue = 10 | pages = 5795–804 | date = November 2001 | pmid = 11698453 | pmc =  | doi = 10.4049/jimmunol.167.10.5795 }}</ref><ref name="pmid10677542">{{cite journal | vauthors = O'Regan S, Traiffort E, Ruat M, Cha N, Compaore D, Meunier FM | title = An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 97 | issue = 4 | pages = 1835–40 | date = February 2000 | pmid = 10677542 | pmc = 26522 | doi = 10.1073/pnas.030339697 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SLC44A1 solute carrier family 44, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23446| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{PBB_Summary
-| section_title =
-| summary_text =
-}}
-==See also==
+== See also ==
 * [[Cluster of differentiation]]
 * [[Solute carrier family]]
-==References==
+== References ==
 {{reflist}}
-==Further reading==
+== Further reading ==
 {{refbegin | 2}}
+* {{cite journal | vauthors = Yuan Z, Tie A, Tarnopolsky M, Bakovic M | title = Genomic organization, promoter activity, and expression of the human choline transporter-like protein 1 | journal = Physiological Genomics | volume = 26 | issue = 1 | pages = 76–90 | date = June 2006 | pmid = 16609143 | doi = 10.1152/physiolgenomics.00107.2005 }}
-{{PBB_Further_reading
+* {{cite journal | vauthors = Fullerton MD, Wagner L, Yuan Z, Bakovic M | title = Impaired trafficking of choline transporter-like protein-1 at plasma membrane and inhibition of choline transport in THP-1 monocyte-derived macrophages | journal = American Journal of Physiology. Cell Physiology | volume = 290 | issue = 4 | pages = C1230-8 | date = April 2006 | pmid = 16319125 | doi = 10.1152/ajpcell.00255.2005 }}
-| citations =
-*{{cite journal  |author1=Yuan Z |author2=Tie A |author3=Tarnopolsky M |author4=Bakovic M |title=Genomic organization, promoter activity, and expression of the human choline transporter-like protein 1 |journal=Physiol. Genomics |volume=26 |issue= 1 |pages= 76–90 |year= 2007 |pmid= 16609143 |doi= 10.1152/physiolgenomics.00107.2005 }}
+* {{cite journal | vauthors = Li D, Wang F, Lai M, Chen Y, Zhang JF | title = A protein phosphatase 2calpha-Ca2+ channel complex for dephosphorylation of neuronal Ca2+ channels phosphorylated by protein kinase C | journal = The Journal of Neuroscience | volume = 25 | issue = 8 | pages = 1914–23 | date = February 2005 | pmid = 15728831 | doi = 10.1523/JNEUROSCI.4790-04.2005 }}
-*{{cite journal  |author1=Fullerton MD |author2=Wagner L |author3=Yuan Z |author4=Bakovic M |title=Impaired trafficking of choline transporter-like protein-1 at plasma membrane and inhibition of choline transport in THP-1 monocyte-derived macrophages |journal=Am. J. Physiol., Cell Physiol. |volume=290 |issue= 4 |pages= C1230–8 |year= 2006 |pmid= 16319125 |doi= 10.1152/ajpcell.00255.2005 }}
+* {{cite journal | vauthors = Traiffort E, Ruat M, O'Regan S, Meunier FM | title = Molecular characterization of the family of choline transporter-like proteins and their splice variants | journal = Journal of Neurochemistry | volume = 92 | issue = 5 | pages = 1116–25 | date = March 2005 | pmid = 15715662 | doi = 10.1111/j.1471-4159.2004.02962.x }}
+* {{cite journal | vauthors = Lecomte MJ, De Gois S, Guerci A, Ravassard P, Faucon Biguet N, Mallet J, Berrard S | title = Differential expression and regulation of the high-affinity choline transporter CHT1 and choline acetyltransferase in neurons of superior cervical ganglia | journal = Molecular and Cellular Neurosciences | volume = 28 | issue = 2 | pages = 303–13 | date = February 2005 | pmid = 15691711 | doi = 10.1016/j.mcn.2004.09.014 }}
-*{{cite journal  | author=Li D |title=A protein phosphatase 2calpha-Ca2+ channel complex for dephosphorylation of neuronal Ca2+ channels phosphorylated by protein kinase C |journal=J. Neurosci. |volume=25 |issue= 8 |pages= 1914–23 |year= 2005 |pmid= 15728831 |doi= 10.1523/JNEUROSCI.4790-04.2005  |name-list-format=vanc| author2=Wang F  | author3=Lai M  | display-authors=3  | last4=Chen  | first4=Y  | last5=Zhang  | first5=JF }}
+* {{cite journal | vauthors = Flajolet M, Rakhilin S, Wang H, Starkova N, Nuangchamnong N, Nairn AC, Greengard P | title = Protein phosphatase 2C binds selectively to and dephosphorylates metabotropic glutamate receptor 3 | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 100 | issue = 26 | pages = 16006–11 | date = December 2003 | pmid = 14663150 | pmc = 307683 | doi = 10.1073/pnas.2136600100 }}
-*{{cite journal  |author1=Traiffort E |author2=Ruat M |author3=O'Regan S |author4=Meunier FM |title=Molecular characterization of the family of choline transporter-like proteins and their splice variants |journal=J. Neurochem. |volume=92 |issue= 5 |pages= 1116–25 |year= 2005 |pmid= 15715662 |doi= 10.1111/j.1471-4159.2004.02962.x }}
+* {{cite journal | vauthors = Takekawa M, Maeda T, Saito H | title = Protein phosphatase 2Calpha inhibits the human stress-responsive p38 and JNK MAPK pathways | journal = The EMBO Journal | volume = 17 | issue = 16 | pages = 4744–52 | date = August 1998 | pmid = 9707433 | pmc = 1170803 | doi = 10.1093/emboj/17.16.4744 }}
-*{{cite journal  | author=Lecomte MJ |title=Differential expression and regulation of the high-affinity choline transporter CHT1 and choline acetyltransferase in neurons of superior cervical ganglia |journal=Mol. Cell. Neurosci. |volume=28 |issue= 2 |pages= 303–13 |year= 2005 |pmid= 15691711 |doi= 10.1016/j.mcn.2004.09.014  |name-list-format=vanc| author2=De Gois S  | author3=Guerci A  | display-authors=3  | last4=Ravassard  | first4=Philippe  | last5=Faucon Biguet  | first5=Nicole  | last6=Mallet  | first6=Jacques  | last7=Berrard  | first7=Sylvie }}
-*{{cite journal  | author=Gerhard DS |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
-*{{cite journal  | author=Humphray SJ |title=DNA sequence and analysis of human chromosome 9 |journal=Nature |volume=429 |issue= 6990 |pages= 369–74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465  | pmc=2734081  |name-list-format=vanc| author2=Oliver K  | author3=Hunt AR  | display-authors=3  | last4=Plumb  | first4=R. W.  | last5=Loveland  | first5=J. E.  | last6=Howe  | first6=K. L.  | last7=Andrews  | first7=T. D.  | last8=Searle  | first8=S.  | last9=Hunt  | first9=S. E. }}
-*{{cite journal  | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285  |name-list-format=vanc| author2=Suzuki Y  | author3=Nishikawa T  | display-authors=3  | last4=Otsuki  | first4=Tetsuji  | last5=Sugiyama  | first5=Tomoyasu  | last6=Irie  | first6=Ryotaro  | last7=Wakamatsu  | first7=Ai  | last8=Hayashi  | first8=Koji  | last9=Sato  | first9=Hiroyuki }}
-*{{cite journal  | author=Flajolet M |title=Protein phosphatase 2C binds selectively to and dephosphorylates metabotropic glutamate receptor 3 |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 26 |pages= 16006–11 |year= 2004 |pmid= 14663150 |doi= 10.1073/pnas.2136600100  | pmc=307683  |name-list-format=vanc| author2=Rakhilin S  | author3=Wang H  | display-authors=3  | last4=Starkova  | first4=N  | last5=Nuangchamnong  | first5=N  | last6=Nairn  | first6=AC  | last7=Greengard  | first7=P }}
-*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
-*{{cite journal  |author1=Takekawa M |author2=Maeda T |author3=Saito H |title=Protein phosphatase 2Calpha inhibits the human stress-responsive p38 and JNK MAPK pathways |journal=EMBO J. |volume=17 |issue= 16 |pages= 4744–52 |year= 1998 |pmid= 9707433 |doi= 10.1093/emboj/17.16.4744  | pmc=1170803 }}
-}}
 {{refend}}
-==External links==
+== External links ==
 * {{MeshName|SLC44A1+protein,+human}}
 {{Clusters of differentiation}}
 {{Membrane transport proteins}}
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
-{{PBB_Controls
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
 [[Category:Solute carrier family]]
 [[Category:Clusters of differentiation]]
 {{membrane-protein-stub}}

v t e Proteins: clusters of differentiation (see also list of human clusters of differentiation)
1–50	CD1 a-c 1A 1B 1D 1E CD2 CD3 γ δ ε CD4 CD5 CD6 CD7 CD8 a CD9 CD10 CD11 a b c d CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50
51–100	CD51 CD52 CD53 CD54 CD55 CD56 CD57 CD58 CD59 CD61 CD62 E L P CD63 CD64 A B C CD66 a b c d e f CD68 CD69 CD70 CD71 CD72 CD73 CD74 CD78 CD79 a b CD80 CD81 CD82 CD83 CD84 CD85 a d e h j k CD86 CD87 CD88 CD89 CD90 CD91 - CD92 CD93 CD94 CD95 CD96 CD97 CD98 CD99 CD100
101–150	CD101 CD102 CD103 CD104 CD105 CD106 CD107 a b CD108 CD109 CD110 CD111 CD112 CD113 CD114 CD115 CD116 CD117 CD118 CD119 CD120 a b CD121 a b CD122 CD123 CD124 CD125 CD126 CD127 CD129 CD130 CD131 CD132 CD133 CD134 CD135 CD136 CD137 CD138 CD140b CD141 CD142 CD143 CD144 CD146 CD147 CD148 CD150
151–200	CD151 CD152 CD153 CD154 CD155 CD156 a b c CD157 CD158 (a d e i k) CD159 a c CD160 CD161 CD162 CD163 CD164 CD166 CD167 a b CD168 CD169 CD170 CD171 CD172 a b g CD174 CD177 CD178 CD179 a b CD180 CD181 CD182 CD183 CD184 CD185 CD186 CD191 CD192 CD193 CD194 CD195 CD196 CD197 CDw198 CDw199 CD200
201–250	CD201 CD202b CD204 CD205 CD206 CD207 CD208 CD209 CDw210 a b CD212 CD213a 1 2 CD217 CD218 (a b) CD220 CD221 CD222 CD223 CD224 CD225 CD226 CD227 CD228 CD229 CD230 CD233 CD234 CD235 a b CD236 CD238 CD239 CD240CE CD240D CD241 CD243 CD244 CD246 CD247 - CD248 CD249
251–300	CD252 CD253 CD254 CD256 CD257 CD258 CD261 CD262 CD263 CD264 CD265 CD266 CD267 CD268 CD269 CD271 CD272 CD273 CD274 CD275 CD276 CD278 CD279 CD280 CD281 CD282 CD283 CD284 CD286 CD288 CD289 CD290 CD292 CDw293 CD294 CD295 CD297 CD298 CD299
301–350	CD300A CD301 CD302 CD303 CD304 CD305 CD306 CD307 CD309 CD312 CD314 CD315 CD316 CD317 CD318 CD320 CD321 CD322 CD324 CD325 CD326 CD327 CD328 CD329 CD331 CD332 CD333 CD334 CD335 CD336 CD337 CD338 CD339 CD340 CD344 CD349 CD350