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Chloralose
Names
IUPAC name
(5ξ)-1,2-O -[2,2,2-Trichloroethylidene]-α-xylo -hexofuranose
Identifiers
85418
ChEMBL
ChemSpider
77572 N 25616 (2R ,5R ,6S ,6aR )-6-hydroxy-2-methyl-furo-5-yl Y 17339596 (1R )-dioxol, (2R ,5R ,6S ,6aR )-6-hydroxy-2-methyl-furo-5-yl Y 162227 (1R )-dioxol, (3aR ,5R ,6S ,6aR )-6-hydroxy-furo-5-yl Y 2005998 (2R ,3aR ,5R ,6S ,6aR )-6-hydroxy-2-methyl-furo-5-yl Y
ECHA InfoCard 100.036.363
EC Number
KEGG
MeSH
Chloralose
85991 40467114 (2R ,3aR ,5R ,6R )-6-hydroxy-2-methyl-furo-5-yl 27525 (2R ,5R ,6S ,6aR )-6-hydroxy-2-methyl-furo-5-yl 16211632 (1R )-dioxol, (2R ,5R ,6S ,6aR )-6-hydroxy-2-methyl-furo-5-yl 186624 (1R )-dioxol, (3aR ,5R ,6S ,6aR )-6-hydroxy-furo-5-yl 2723807 (2R ,3aR ,5R ,6S ,6aR )-6-hydroxy-2-methyl-furo-5-yl
RTECS number
InChI=1S/C8H11Cl3O6/c9-8(10,11)7-16-5-3(14)4(2(13)1-12)15-6(5)17-7/h2-7,12-14H,1H2
N Key: OJYGBLRPYBAHRT-UHFFFAOYSA-N
N
OCC(O)C1OC2OC(OC2C1O)C(Cl)(Cl)Cl
C(C(C1C(C2C(O1)OC(O2)C(Cl)(Cl)Cl)O)O)O
Properties
C 8 H 11 Cl 3 O 6
Molar mass
−1
Melting point
176 °C (349 °F; 449 K)
Hazards
Occupational safety and health
Main hazards
Harmful if swallowedHarmful if inhaled
Related compounds
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
Chemical compound
Chloralose is an avicide , rodenticide used to kill mice in temperatures below 15 °C. It is also widely used in neuroscience and veterinary medicine as an anesthetic and sedative .[1]
Chemically, it is a chlorinated acetal derivative of glucose .
It is listed in Annex I of Directive 67/548/EEC with the classification Harmful (Xn )
References
^ Silverman J, Muir WW (Jun 1993). "A review of laboratory animal anesthesia with chloral hydrate and chloralose". Lab Anim Sci . 43 (3): 210–6. PMID 8355479 .
Alcohols Barbiturates Benzodiazepines Carbamates Flavonoids Imidazoles Kava constituentsMonoureides Neuroactive steroids Nonbenzodiazepines Phenols Piperidinediones Pyrazolopyridines Quinazolinones Volatiles /gases Others/unsorted
3-Hydroxybutanal α-EMTBL AA-29504 Alogabat Avermectins (e.g., ivermectin )Bromide compounds (e.g., lithium bromide , potassium bromide , sodium bromide )Carbamazepine Chloralose Chlormezanone Clomethiazole Darigabat DEABL Deuterated etifoxine Dihydroergolines (e.g., dihydroergocryptine , dihydroergosine , dihydroergotamine , ergoloid (dihydroergotoxine) )DS2 Efavirenz Etazepine Etifoxine Fenamates (e.g., flufenamic acid , mefenamic acid , niflumic acid , tolfenamic acid )Fluoxetine Flupirtine Hopantenic acid KRM-II-81 Lanthanum Lavender oil Lignans (e.g., 4-O-methylhonokiol , honokiol , magnolol , obovatol )Loreclezole Menthyl isovalerate (validolum) Monastrol Niacin Niacinamide Org 25,435 Phenytoin Propanidid Retigabine (ezogabine) Safranal Seproxetine Stiripentol Sulfonylalkanes (e.g., sulfonmethane (sulfonal) , tetronal , trional )Terpenoids (e.g., borneol )Topiramate Valerian constituents (e.g., isovaleric acid , isovaleramide , valerenic acid , valerenol )
