Chloralose

Chloralose

Names
IUPAC name 1,2-O-[2,2,2-Trichloroethylidene]-α-gluco-hexofuranose
Identifiers
CAS Number	15879-93-3 Y[EBI]
3D model (JSmol)	Interactive image
Beilstein Reference	85418
ChEBI	CHEBI:81902
ChEMBL	ChEMBL2104181 Y
ChemSpider	5414376 Y
ECHA InfoCard	100.036.363
EC Number	240-016-7
KEGG	C18707 N
MeSH	Chloralose
PubChem CID	7057995 40467114 (2R,3aR,5R,6R)-6-hydroxy-2-methyl-furo-5-yl 27525 (2R,5R,6S,6aR)-6-hydroxy-2-methyl-furo-5-yl 16211632 (1R)-dioxol, (2R,5R,6S,6aR)-6-hydroxy-2-methyl-furo-5-yl 186624 (1R)-dioxol, (3aR,5R,6S,6aR)-6-hydroxy-furo-5-yl 2723807 (2R,3aR,5R,6S,6aR)-6-hydroxy-2-methyl-furo-5-yl 85991
RTECS number	FM9450000
UNII	238BZ29MUE Y
CompTox Dashboard (EPA)	DTXSID4020088
InChI InChI=1S/C8H11Cl3O6/c9-8(10,11)7-16-5-3(14)4(2(13)1-12)15-6(5)17-7/h2-7,12-14H,1H2/t2-,3+,4-,5-,6-,7-/m1/s1 Y Key: OJYGBLRPYBAHRT-IPQSZEQASA-N Y InChI=1/C8H11Cl3O6/c9-8(10,11)7-16-5-3(14)4(2(13)1-12)15-6(5)17-7/h2-7,12-14H,1H2/t2-,3+,4-,5-,6-,7-/m1/s1 Key: OJYGBLRPYBAHRT-IPQSZEQABF
SMILES C([C@H]([C@@H]1[C@@H]([C@@H]2[C@H](O1)O[C@@H](O2)C(Cl)(Cl)Cl)O)O)O
Properties
Chemical formula	C8H11Cl3O6
Molar mass	309.52 g·mol−1
Melting point	176 to 182 °C (349 to 360 °F; 449 to 455 K)
Hazards
Occupational safety and health (OHS/OSH):
Main hazards	Harmful if swallowed Harmful if inhaled
GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H301, H332, H336, H410
Precautionary statements	P261, P264, P270, P271, P273, P301+P310, P304+P312, P304+P340, P312, P321, P330, P391, P403+P233, P405, P501
Related compounds
Related compounds	Chloral hydrate
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Chloralose (also known as α-chloralose) is an avicide, and a rodenticide used to kill mice in temperatures below 15 °C. It is also widely used in neuroscience and veterinary medicine as an anesthetic and sedative.

Chemically, it is a chlorinated acetal derivative of glucose.

It is listed in Annex I of Directive 67/548/EEC with the classification Harmful (Xn)

Chloralose exerts barbiturate-like actions on synaptic transmission in the brain, including potent effects at inhibitory γ-aminobutyric acid type A (GABA_A) receptors. A structural isomer of chloralose, β-chloralose (also called parachloralose in older literature), is inactive as a GABA_A modulator and also as a general anesthetic.