John Gurdon

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Sir John Gurdon in Magdalene College, October 2012

Sir John Bertrand Gurdon (born October 2, 1933 in Dippenhall , Hampshire , England ) is a British developmental biologist and professor emeritus at the University of Cambridge .

Gurdon explored the importance of the nucleolus of the cell. He also laid the foundation for animal cloning with his work on cell nucleus transplants . In 2012 he was awarded the Nobel Prize for Medicine together with Shin'ya Yamanaka .

Life

After graduating from Eton College , Gurdon received a BA in Zoology from Christ Church College , Oxford , in 1956 and a D.Phil in 1960 . in embryology . He subsequently stayed at Christ Church College, but had research stays at the California Institute of Technology in Pasadena and the Carnegie Institution in Baltimore . In 1983, he succeeded Alan Lloyd Hodgkin as a professor at the University of Cambridge , which he held until 1990. In 1995 he was knighted as a Knight Bachelor . From 1995 to 2002 he was a Masters at Magdalene College, Cambridge .

Gurdon has headed the Wellcome Trust / Cancer Research UK Institute at the University of Cambridge, now known as the Gurdon Institute , since 1990 . He himself continues to lead one of the 20 research groups at this institute (as of 2016).

Act

The fact that Gurdon was able to raise adult, sexually mature animals from cells to which the nucleus of different cells at different stages of maturity had been transplanted , demonstrated that the genome (with a few exceptions) does not change during the development of an individual. However, the cytoplasm contains factors that influence gene expression . He was also able to show that foreign mRNA introduced into cells is expressed .

Gurdon carried out many of his pioneering work on oocytes (= egg cells ) of clawed frogs ( Xenopus laevis ).

Awards (selection)

Fonts (selection)

  • JB Gurdon: The developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpoles . In: Journal of Embryology and Experimental Morphology . tape 10 , 1962, pp. 622-640 ( [1] ).

literature

Web links

Commons : John Gurdon  - collection of pictures, videos and audio files

Individual evidence

  1. ↑ Scientific Medal Winners (PDF, 108 kB) at zsl.org; accessed on April 17, 2018.
  2. ^ A b Académie royale des Sciences, des Lettres et des Beaux-Arts de Belgique: John Gurdon ( Memento from October 31, 2015 in the Internet Archive )
  3. ↑ Prizewinners 1961–1981 at feldbergfoundation.org; Retrieved December 16, 2010
  4. ^ Goethe University - laureate since 1952. In: uni-frankfurt.de. March 14, 2016, accessed January 23, 2016 .
  5. ↑ Book of Members 1780 – present, Chapter G. (PDF; 931 kB) In: American Academy of Arts and Sciences (amacad.org). Retrieved April 17, 2018 .
  6. ^ The Royal Medals 1950–1989 ( Memento from January 7, 2011 in the Internet Archive ) on the website of the Royal Society
  7. ↑ John Bertrand Gurdon (PDF; 2.7 MB) at jsps.go.jp; Retrieved December 13, 2010
  8. ^ The 1989 Wolf Foundation Prize in Medicine at wolffund.org.il; Retrieved December 13, 2010
  9. ^ John Gurdon - List des membres de l'Académie des sciences / G - Listes par ordre alphabétique - Listes des membres - Memb. In: academie-sciences.fr. Retrieved January 24, 2016 (French).
  10. ↑ Copley recent winners: 1990 - present day ( memento of December 1, 2010 in the Internet Archive ) at royalsociety.org; Retrieved December 13, 2010
  11. ^ Past Winners - Rosenstiel Award - Rosenstiel Basic Medical Sciences Research Center - Brandeis University. In: brandeis.edu. Retrieved January 23, 2016 .
  12. ^ Albert Lasker Basic Medical Research Award. 2009 Winners John Gurdon and Shinya Yamanaka at laskerfoundation.org; Retrieved December 12, 2010
personal data
SURNAME Gurdon, John
ALTERNATIVE NAMES Gurdon, John B .; Gurdon, John Bertrand
BRIEF DESCRIPTION British evolutionary biologist
DATE OF BIRTH October 2, 1933
PLACE OF BIRTH Dippenhall , Hampshire, England