Nageikina made her debut in the World Cup in Oberstdorf in February 1986 and finished sixth over 20 km classic. In the 1987/88 season she came in the top ten four times in the World Cup. With third place in the 10 km freestyle in Rovaniemi, she achieved her first podium and finished ninth in the overall World Cup at the end of the season. At the 1988 Winter Olympics in Calgary , she won the gold medal with the Soviet relay. In addition, it was eighth over 5 km classic and fourth over 10 km classic. In the following season she reached the podium again in Kavgolovo at her only start of the season in the World Cup with second place over 15 km. After three third places at the beginning of the 1989/90 season, she won her only individual victory in the World Cup over 10 km classic in Bohinj . This was followed in Lahti with the relay and over 5 km freestyle in each case second place and at the end of the season fourth place in the overall World Cup. In the 1990/91 season, like in the previous season, she came in the top ten at all World Cup races, including second place over 30 km classic in Minsk and with the relay in Oslo . In Falun she won the relay and at the end of the season she finished eighth in the overall World Cup. At the Nordic World Ski Championships in 1991 in Val di Fiemme , she achieved 14th place over 10 km freestyle, eighth place over 15 km classic and fifth place over 30 km freestyle. In the following season she could not repeat her strong results. After third place at the beginning of the season in Silver Star , she achieved two results in the top ten in six participations and took 12th place in the overall World Cup. Also in the 1992/93 season she achieved two placings in the top ten and finally 13th place in the overall World Cup. Her best result was fourth place over 30 km classic in Kavgolovo. At the season highlight, the Nordic World Ski Championships in 1993 in Falun, she finished 31st over 30 km freestyle and 19th over 15 km classic. After five top ten placements in the first half of the 1993/94 season, she achieved 19th place in the pursuit race at the 1994 Winter Olympics in Lillehammer , 16th place over 5 km classic and ninth place over 30 km classic. This was followed by second place in the relay in the World Cup in Lahti and first place in Falun. At the last World Cup of the season in Thunder Bay , she came third over 5 km classic and finally finished sixth in the overall World Cup. After taking a break in the 1994/95 season, she came in the 1995/96 season three times under the top ten in the World Cup singles. In addition, she was third with the relay in Santa Caterina Valfurva and won with the relay in Nové Město and Oslo. She finished the season in 13th place in the overall World Cup. Her best individual result in the World Cup the following season was seventh in the 30 km freestyle in Oslo. At the Nordic World Ski Championships in Trondheim in 1997 , she was tenth over 30 km classic. Also in the season she took third place in Davos , second place in Brusson and first place in Oslo. At the end of the season she reached 18th place in the overall World Cup. In the 1997/98 season she came eight times in the top ten in the individual World Cup, including once third and twice second. In addition, she won in the Fiemme Valley and took third place in Lahti with the relay. At the season highlight, the 1998 Winter Olympics in Nagano , she achieved 16th place over 15 km classic. She finished the season in sixth place in the overall World Cup. After finishing 16th and eighth at the beginning of the 1998/99 season in Toblach , she won in Davos together with the relay. In the further course of the season she achieved third place over 10 km classic in Nové Mesto and second place over 15 km classic in Falun. At the Nordic World Ski Championships in 1999 in Ramsau am Dachstein , she finished 11th in the pursuit race and fourth place over 5 km classic and over 30 km classic. At the end of the season she won in Falun and in Oslo with the relay and reached seventh place in the overall World Cup.
In the 1999/2000 season Nageikina came in the World Cup 11 times in the top ten, including two third and one second place, reaching 15th place in the Sprint World Cup and tenth place in the overall World Cup. She also started in the Marathon Cup that season . She won the Marcialonga , the König-Ludwig-Lauf and the Wasalauf and thus won the overall ranking. In the following season she reached six top ten positions in the individual World Cup. In January 2001 she became Russian champion over 30 km in Krasnogorsk and won the Dolomites run . At the Nordic World Ski Championships in 2001 in Lahti , she finished 11th over 15 km classic and 11th over 10 km classic. She finished the season in 16th place in the overall World Cup. After she moved from the Russian Federation to the Belarusian Federation after the 2000/01 season, she came in the 2001/02 season in 14 competitions in the World Cup singles, twice under the top ten, including third place in the 15 km mass start race in Fiemme Valley. Her best result at the season highlight, the 2002 Winter Olympics in Salt Lake City, was fifth in both the 15 km mass start race and with the relay. In March 2002 she won the Wasalauf for the second time and reached 23rd place in the overall World Cup at the end of the season. Her best individual result in the World Cup in the 2002/03 season was seventh place in the 15 km mass start race in Otepää . Her best placings at the Nordic World Ski Championships in 2003 in Val di Fiemme were eighth in the skiathlon and fifth in the relay. From the 2003/04 season she started again for the Russian Federation. At the beginning of the 2003/04 season she won her only victory in the Continental Cup in Krasnogorsk . Two World Cup races followed, each of which she finished in fourth place. In the following seasons she started mainly in FIS races . She ran her last international race in January 2007 at the World Cup in Rybinsk , which she finished in 27th place in the 15 km mass start race.