Defending champion was Rafael Nadal in the singles, who could not convert a match point in the semifinals against Dominic Thiem and was eliminated. Thiem won the final against Nicolás Almagro in three sets with 7: 6 2 , 3: 6, 7: 6 and thus won his fourth individual title in his fifth final. Almagro broke a 15-game losing streak to David Ferrer en route to the final to reach his 22nd final on the tour. Last year, Jarkko Nieminen and André Sá won doubles, but they didn't start this time. The final decided the top seeded Juan Sebastián Cabal and Robert Farah from Colombia against Íñigo Cervantes and Paolo Lorenzi 6: 3, 6: 0 for themselves.
The field of participants in the single competition consisted of 28 players, that of the doubles competition consisted of 16 pairs. The total prize pool was $ 523,470; total financial liabilities were $ 598,865.
At the Argentina Open 2016, the following prize money and world ranking points were paid out or credited for reaching the respective round. Players who passed the qualification received the specified qualification points in addition to those for reaching the respective round. Otherwise, the amounts are not cumulative (amounts for the double competition per team).
Rafael Nadal
Jarkko Nieminen André Sá
Dominic Thiem
Juan Sebastián Cabal Robert Farah
Dušan Lajović (76)
Marco Cecchinato
Gastão Elias
O. Dolhopolov
J. Isner
J.-W. Tsonga
P. Cuevas
