List of sons and daughters of Rome
The following list contains important people born in Rome , regardless of their later sphere of activity.
The list does not claim to be complete.
A.
- Ahmed Abdelwahed (* 1996), track and field athlete
- Alberto Abruzzese (* 1942), literary and media scholar
- Francesco Abussi (* 1947), cameraman, screenwriter and film director
- Alessandra Acciai (born 1965), actress
- Filippo Acciaiuoli (1700–1766), papal diplomat, bishop of Ancona and cardinal
- Adeodatus I († 618), Pope (615–618)
- Adeodatus II († 676), Pope (672–676)
- Giorgio Agamben (* 1942), philosopher and lawyer and editor of the Italian editions of Walter Benjamin's writings
- Agapitus I († 536), Pope (535–536)
- Aegidius Romanus (around 1243–1316), Augustinian hermit
- Agnes of Rome (around 237-250), martyr
- Luciana Aigner-Foresti (* 1936), archaeologist, ancient historian and Etruscanologist
- Andrea Aiuti (1849–1905), cardinal of the Roman Catholic Church
- Giovanni Francesco Albani (1720–1803), Cardinal Curia of the Roman Catholic Church
- Giuseppe Albani (1750–1834), cardinal of the Roman Catholic Church
- Marcella Albani (1899–1959), actress, film producer and author
- Vincenzo Albrici (1631–1696), organist, conductor and composer
- Pietro Aldobrandini (1571–1621), cardinal of the Roman Catholic Church
- Alessandro Alessandroni (1925–2017), musician
- Alexander I († 115), Bishop of Rome (106–115)
- Alfons de Borbón (1941–1956), member of the Spanish Bourbon House
- Gregorio Allegri (1582–1652), priest, composer and tenor singer
- Guido Altarelli (1941–2015), theoretical physicist
- Giovanna Amati (* 1962), racing car driver
- Domenico Amici (1808-?), Artist
- Niccolò Ammaniti (* 1966), writer
- Franco Amurri (* 1958), film director and screenwriter
- Anaklet († 88 (?)), Pope, around 79–88
- Anaclet II (around 1090–1138), antipope to Pope Innocent II.
- Anastasius III. († 913), Pope from 911 to 913
- Giulio Andreotti (1919–2013), politician
- Lucilla Andreucci (* 1969), long-distance runner
- Giovanni Francesco Anerio (1567–1630), musician and composer
- Roberta Angelilli (* 1965), politician
- Fiorenzo Angelini (1916–2014), cardinal of the Roman Catholic Church
- Elio de Angelis (1958–1986), racing car driver
- Ambra Angiolini (* 1977), film actress
- Paolo Francesco Antamori (1712–1795), Bishop of Orvieto and Cardinal
- Luca Antei (* 1992), soccer player
- Richard Antinucci (* 1981), American racing driver
- Mirko Antonucci (* 1999), football player
- Silvio Antoniano (1540–1603), lawyer, theologian, cardinal
- Flavio Apel (* 1988), artist
- Guillaume Apollinaire (1880–1918), French writer and art critic of Italian-Polish descent
- Alberto Aquilani (* 1984), football player
- Tullia d'Aragona (1510–1556), courtesan and poet and philosopher of the Renaissance
- Vittoria Archilei , called "la Romanina" (* approx. 1560 - around 1645), famous singer (soprano)
- Asia Argento (* 1975), actress and director
- Dario Argento (* 1940), film director and screenwriter
- Marcello Argilli (1926–2014), lawyer, journalist, writer, children's book author and comic author
- Marco Ariano (* 1961), jazz drummer and performance artist
- Domenico Armellini (1769–1828), Bishop of Terni
- Pompeio Arrigoni (1552–1616), cardinal of the Roman Catholic Church
- Augustus (63 BC - 14 AD), Roman Emperor
- Aldo Aureggi (1931-2020), fencer
- Mark Aurel (121–180), Roman emperor
- Giuseppe Aureli (1858–1929), painter
- Carlo Aymonino (1926–2010), architect and urban planner
B.
- Guido Baccelli (1830–1916), physician and politician
- Marcello Bacciarelli (1731-1818), painter of the baroque and classicism
- Giovanni Baglione (1571–1643), painter and art writer
- Jorge de Bagration (1944–2008), from 1991 recognized head of the former royal family of Georgia
- Pio Baldi (* 1945), architect
- Alfredo Balloni (* 1989), racing cyclist
- Silvia Baraldini (* 1947), activist
- Federico Barba (* 1993), football player
- Paola Barbara (1912–1989), actress
- Luca Barbarossa (* 1961), singer
- Antonio Barberini (1607–1671), Duke of Urbino, Archbishop of Reims, son of Carlo Barberini and nephew of Pope Urban VIII.
- Carlo Barberini (1630–1704), cardinal
- Enzo Barboni (1922–2002), screenwriter and director
- Andrea Bargnani (* 1985), basketball player
- Cecilia Bartoli (* 1966), mezzo-soprano
- Domenico Bartolini (1813–1887), Curia Cardinal of the Roman Catholic Church
- Giulio Battelli (1904–2005), archivist, palaeographer, literary scholar and university professor
- Mattia Battistini (1856–1928), opera and concert singer
- Alessandro Bausani (1921–1988), Iranist, Islamic scholar and linguist
- Lamberto Bava (* 1944), director, screenwriter and film producer
- Giuseppe Gioachino Belli (1791–1863), poet
- Michele Belli (1753–1822), Curia Bishop
- Giordano Bellincampi (* 1965), Danish conductor of Italian origin
- Benedict VI. († 974), Pope from 973 to 974
- Benedict VII († 983), Pope from 974 to 983
- Orazio Benevoli (1605–1672), conductor and composer
- Dario Beni (1889–1969), cyclist and sports official
- Marianna Benti Bulgarelli , called "la Romanina" (around 1684–1734), opera singer (soprano)
- Vincent Beretti (1781–1842), Russian and Ukrainian architect of Italian descent
- Fulvio Bernardini (1905–1984), football player and coach
- Luigi Bernini (1612–1681), sculptor, architect and machine designer
- Matteo Berrettini (* 1996), tennis player
- Andrea Bertolacci (* 1991), football player
- Goffredo Bettini (* 1952), politician
- Max Biaggi (* 1971), motorcycle racer
- Isabella Biagini (1940–2018), actress, radio announcer and model
- Laura Biagiotti (1943–2017), fashion designer
- Angelo Bianchi (1817–1897), Curia Cardinal of the Roman Catholic Church
- Daniela Bianchi (* 1942), actress
- Pedro Biava Ramponi (1902–1972), Colombian composer
- Susanne Bickel (* 1960), Swiss Egyptologist
- Pietro Fumasoni Biondi (1872–1960), cardinal of the Roman Catholic Church
- Lelio Biscia (1575-1638), cardinal
- Alessandro Blasetti (1900–1987), film director
- Ilary Blasi (* 1981), actress and photo model
- Lina Bo Bardi (1914–1992), Brazilian architect and designer of Italian origin
- Giovanni Boccamazza († 1309), bishop and cardinal
- Angelo Bolaffi (* 1946), philosopher and political scientist
- Giorgio Bolognetti (1595–1686), Bishop of Rieti
- Lucien-Louis-Joseph-Napoleon Bonaparte (1828–1895), French cardinal of the Roman Catholic Church
- Boniface of Tarsus († around 306), Roman early church martyr
- Boniface II. († 532), Pope from 530 to 532
- Boniface III († 607), Pope from February 19 to November 12, 607
- Mario Bonnard (1889–1965), actor, film director and screenwriter
- Roberto Bordi (* 1946), Franciscan, auxiliary bishop in El Beni o Beni
- Giovanni Antonio Boretti (around 1640 - 1672), opera singer
- Sal Borgese (born 1937), actor and stuntman
- Camillo Filippo Ludovico Borghese (1775–1832), Prince of Sulmona and Rossano
- Francesco Scipione Maria Borghese (1697–1759), bishop and cardinal
- Junio Valerio Borghese (1906–1974), naval officer and politician
- Scipione Borghese (1734–1782), cardinal
- Cesare Borgia (1475–1507), Renaissance ruler
- Lucrezia Borgia (1480–1519), princess
- Raoul Bova (* 1971), actor and photo model
- Cesare Bovo (born 1983), football player
- Francesco Borgongini Duca (1884–1954), cardinal of the Roman Catholic Church
- Christina von Braun (* 1944), German cultural scientist, gender theorist, author and filmmaker
- Pierre Savorgnan de Brazza (1852–1905), French naval officer and African traveler of Italian origin
- Scipione Breislak (1750–1826), Italian geologist of Swedish origin
- Alex Britti (* 1968), songwriter, guitarist and singer
- Romaine Brooks (1874–1970), American painter and sculptor
- Sandro Brugnolini (* 1931), musician and film composer
- Lucia Brunacci (1848–1931), model, muse and lover of Anselm Feuerbach
- Giovanni Brunelli (1795–1861), papal diplomat and cardinal
- Gianmaria Bruni (* 1981), racing car driver
- Cristian Bucchi (* 1977), soccer player and coach
- Gaspare del Bufalo (1786–1837), founder of the Congregation of Missionaries of the Precious Blood (CPPS), is venerated as a saint in the Roman Catholic Church
- Nastassja Burnett (* 1992), tennis player
- Vittoria Bussi (* 1987), racing cyclist
- Guido Buzzelli (1927–1992), comic book artist and illustrator
C.
- Nicola Cabibbo (1935–2010), physicist and university professor
- Giulio Caccini (1551-1618), composer
- Giuseppe Cades (1750–1799), painter and graphic artist
- Cecilia of Rome (* around 200 AD; † around 230), Christian saint, virgin and martyr
- Gaius Iulius Caesar (* 100 BC; † 44 BC), Roman statesman, general and author
- Bonifazio Caetani (1567–1617), Bishop of Cassano all'Jonio, Archbishop of Taranto and Cardinal
- Niccolò Caetani di Sermoneta (1526–1585), archbishop and cardinal
- Prospero Caffarelli (1593-1659), cardinal
- Mario Caiano (1933–2015), film director, screenwriter and producer
- Giorgio Calcaterra (* 1972), long-distance and ultra-marathon runner
- Calpurnia (* around 77 BC), third wife of Gaius Iulius Caesar
- Francesco Gaetano Caltagirone (* 1943), entrepreneur
- Filippo Camassei (1848–1921), Patriarch of Jerusalem and Cardinal of the Roman Catholic Church
- Mario Camerini (1895–1981), director
- Achille Campanile (1899–1977), journalist and playwright
- Vincenzo Camuccini (1771–1844), painter
- Annamaria Cancellieri (* 1943), politician, interior minister from 2011 to 2013
- Antonio Candreva (* 1987), football player
- Justus of Canterbury († between 627 and 631), missionary, Archbishop of Canterbury
- Annibale Capalti (1811–1877), cardinal of the Roman Catholic Church
- Daniele Capezzone (* 1972), journalist and politician
- Remo Capitani (1927-2014), actor
- Gianantonio Capizucchi (1515–1569), cardinal of the Roman Catholic Church
- Gaetano Capocci (1811–1898), church musician, organist and composer
- Cristiana Capotondi (* 1980), actress
- Benedetta Cappa (1897–1977), painter of futurism
- Kaspar Capparoni (born 1964), actor
- Angelo Capranica (around 1415 - 1478), bishop and cardinal
- Luigi Carnacina (1888–1981), cook
- Giulio Carpegna (1760–1826), papal diplomat, last inquisitor in Malta
- Liam Caruana (* 1998), tennis player
- Giovanni Battista Casali del Drago (1838–1908), priest and cardinal of the Roman Catholic Church
- Claudio Casciolini (1697–1760), composer
- Mario Caserini (1874–1920), film director, actor and screenwriter
- Carlo Cassola (1917–1987), writer
- Fabio Massimo Castaldo (* 1985), politician
- Francesco Castellacci (* 1987), racing car driver
- Giuseppe Maria Castellani (1798-1854), Curia Bishop
- Enzo G. Castellari (* 1938), director
- Luciana Castellina (* 1929), politician and journalist
- Sergio Castellitto (* 1953), actor, film director and screenwriter
- Danilo Cataldi (* 1994), football player
- Marcus Porcius Cato the Younger (* 95 BC; † 46 BC), Roman general and statesman
- Emilio de 'Cavalieri (1550–1602), composer, organist, diplomat, choreographer and dancer
- Pietro Cavallini (around 1250, † around 1330), painter
- Enrico Cecchetti (1850–1928), ballet dancer, pantomime, ballet master and ballet teacher
- Suso Cecchi D'Amico (1914-2010), screenwriter
- Angelo Celsi (around 1600 - 1671), cardinal
- Beatrice Cenci (1577–1599), Roman patrician
- Vincenzo Cerami (1940–2013), writer, dramaturge and screenwriter
- Carlo Cerri (1610–1690), bishop and cardinal
- Michela Cerruti (* 1987), racing car driver
- Valentina Cervi (* 1976), actress
- Alessandro Cesarini (around 1475 - 1542), bishop and cardinal
- Alessandro Cesarini (1592–1644) (1592–1644), bishop and cardinal
- Giuliano Cesarini the Elder (1398–1444), canonist, diplomat and cardinal
- Andrea de Cesaris (1959–2014), racing car driver
- Pierdonato Cesi (1585-1656), cardinal
- Ross Cheever (* 1964), American racing car driver
- Gaetano Chiaveri (1689–1770), builder and architect
- Luciano Ciancola (1929–2011), racing cyclist
- Flavio Chigi (1711–1771), Roman Catholic Curia Cardinal
- Flavio Chigi (1810-1885), Roman Catholic cardinal
- Ottavio Cinquanta (* 1938), sports official
- Marco Cioci (* 1975), racing car driver
- Flavio Cipolla (* 1983), tennis player
- Pietro Ciriaci (1885–1966), cardinal of the Roman Catholic Church
- Franco Citti (1935–2016), actor
- Chiara Civello (* 1975), jazz musician
- Clement of Rome (* around 50; † 97 or 101), one of the Apostolic Fathers
- Clement III. († 1191), Pope from 1187 to 1191
- Clement X. (1590–1676), Pope from 1670 to 1676
- Muzio Clementi (1752–1832), classical composer
- Filippo Coarelli (* 1936), classical archaeologist, Graecist and ancient scholar
- Maria Rosa Coccia (1759–1833), composer, first woman with the title "maestra di capella romana"
- Celestine III. (* about 1106; † 1198), Pope from 1191 to 1198
- Stefano Colantuono (* 1962), football player and coach
- Piergiorgio Colautti (* 1934), painter and sculptor
- Pino Colizzi (* 1937), film actor and voice actor
- Tonino Delli Colli (1923-2005), cameraman
- Michael Collins (* 1930), American astronaut
- Giovanni Colonna (* 1934), archaeologist
- Girolamo Colonna di Sciarra (1708–1763), Cardinal Chamberlain of the Roman Catholic Church
- Pompeo Colonna (1479–1532), Cardinal of the Roman Catholic Church, Bishop of Rieti
- Prospero Colonna (* around 1410, † 1463), cardinal of the Roman Catholic Church
- Flavio Colusso (* 1960), composer, librettist, conductor and choir director
- Bianca Commichau-Lippisch (1890–1968), German painter
- Domenico Comparetti (1835–1927), classical philologist, papyrologist and folklorist
- Ennio De Concini (1923–2008), screenwriter and film director
- Ercole Consalvi (1757–1824), cardinal of the Roman Catholic Church and diplomat of the Papal States
- Bernardo Maria Conti (1664–1730), cardinal of the Roman Catholic Church
- Carlo Conti (1556–1615), Bishop of Ancona and cardinal
- Giovanni Conti (1414–1493), bishop and cardinal
- Sergio Corbucci (1927–1990), film director
- Ignazio Corrao (* 1984), politician
- Renato Corsetti (* 1941), linguist, activist of the Esperanto movement and from 2001 to 2007 chairman of the World Esperanto Federation
- Simone Corsi (* 1987), motorcycle racer
- Paola Cortellesi (* 1973), actress and presenter
- Daniele Corvia (* 1984), football player
- Franco Costa (1934-2015), painter
- Marcello Costalunga (1925-2010), Vatican Archbishop of the Curia
- Antonio Cotogni (1831-1918), opera singer
- Carlo Cremonesi (1866–1943), cardinal of the Roman Catholic Church
- Alessandro Crescenzi , Bishop and Cardinal
- Pier Paolo Crescenzi (1572–1645), cardinal of the Roman Catholic Church
- Marcus Antonius Creticus († 71 BC), Roman politician
- Emanuele Crialese (* 1965), screenwriter and film director
- Gianluca Curci (* 1985), soccer goalkeeper
D.
- Massimo D'Alema (* 1949), politician (PD), Prime Minister of Italy from 1998 to 2000, Foreign Minister from 2006 to 2008
- Joe D'Amato (1936–1999), film director and producer, cameraman and screenwriter
- Mirella D'Angelo (born 1956), actress
- Piero D'Inzeo (1923-2014), show jumper
- Giacomo Dalla Torre del Tempio di Sanguinetto (1944–2020), Grand Master of the Order of Malta
- Wolfango Dalla Vecchia (1923–1994), composer, organist and teacher
- Paolo Damiani (* 1952), jazz bassist and big band leader
- Enrico Dante (1884–1967), Curia Cardinal of the Roman Catholic Church
- Clelio Darida (1927–2017), lawyer and politician (DC)
- Aurelio De Laurentiis (* 1949), film producer and football official
- Marco De Luca (* 1981), walker
- Luciano De Paolis (* 1941), bobsleigh athlete and two-time Olympic champion
- Boris de Rachewiltz (1926–1997), Egyptologist
- Fabrizio De Simone (* 1971), racing car driver
- Cosimo de Torres (1584–1642), cardinal and archbishop
- Mimmo Dei (1909–1985), sports patron and racing team owner
- Innocenzo Del Bufalo de 'Cancellieri (1565 / 66-1610), cardinal
- Luigi Del Drago (1776–1845), Cardinal to the Curia
- Marisa Del Frate (1931–2015), singer and actress
- Friedrich Christian Delius (* 1943), German writer
- Giuseppe Della Porta Rodiani (1773–1841), cardinal
- Carlo Delle Piane (1936-2019), actor
- Francesca Dellera (* 1965), actress and model
- Giovanni Devoti (1744–1820), Bishop of Anagni and Curia Bishop
- Agostino Di Bartolomei (1955-1994), football player
- Luigi Di Biagio (* 1971), football player and coach
- Paolo Di Canio (* 1968), football player
- Alberto Di Chiara (* 1964), football player
- Angelo Di Livio (* 1966), football player and coach
- Grazia Di Michele (* 1955), Cantautrice
- Carlo Di Palma (1925-2004), cameraman
- Camillo Di Pietro (1806–1884), papal diplomat and cardinal of the Roman Catholic Church
- Guerino Di Tora (* 1946), Roman Catholic clergyman and auxiliary bishop in Rome
- Marco Di Vaio (* 1976), football player
- Francesco Diodati (* 1983), jazz musician
- Stefano Dionisi (born 1966), actor
- Domitian (51–96), Roman Emperor from 81 to 96
- Maurizio Domizzi (* 1980), football player
- Cristiano Doni (* 1973), football player
- Piero Dorazio (1927–2005), painter
- Gianni Dova (1925–1991), painter
- Mario Draghi (* 1947), bank manager, economist and President of the European Central Bank since 2011
- Heinrich Dressel (1845–1920), German epigraphist and numismatist
- Serafino Dubois (1817–1899), chess player
E.
- Eduard Ender (1822–1883), Austrian painter
- Guglielmo Epifani (* 1950), politician and trade unionist
- Eugenia of Rome (* around 180; † 258 or 262), Christian martyr
- Franco Evangelisti (1926–1980), composer, improvisation musician and music theorist
- Julius Evola (1898–1974), cultural philosopher, esotericist and racial theorist
F.
- Luce Fabbri (1908–2000), anarchist and publicist
- Fabianus (* before 200; † 250), martyr and from 236 to 250 bishop of Rome
- Aldo Fabrizi (1905–1990), film actor and director
- Federica Faiella (* 1981), figure skater
- Franca Falcucci (1926-2014), politician
- Giovanni Fallani (1910–1985), Archbishop of the Curia
- Antonio Faraò (* 1965), jazz pianist
- Simone Farina (* 1982), football player
- Alessandro Farnese (1545–1592), general and diplomat
- Pier Luigi II. Farnese (1503–1547), illegitimate son of Alessandro Farnese (1468–1549), later Pope Paul III.
- Pierfrancesco Favino (born 1969), film actor
- Felicianus († around 305), Christian and martyr in Rome, place of birth Rome uncertain
- Felicitas († around 166), Roman Christian and martyr
- Felix I († 274), Bishop of Rome from 269 to 274
- Enrico Fermi (1901–1954), nuclear physicist and Nobel Prize winner (1938)
- Giuseppe Ferraioli (1929–2000), Roman Catholic Archbishop and diplomat
- Giancarlo Ferrando (1939-2020), cameraman
- Niccola Ferrarelli (1762–1843), Curia Bishop
- Attilio Ferraris (1904-1947), football player
- Ferruccio Ferrazzi (1891–1978), painter and sculptor
- Anna Maria Ferrero (1934-2018), actress
- Giuseppe Ferretto (1899–1973), cardinal of the Roman Catholic Church
- Sabrina Ferilli (* 1964), film and theater actress
- Gabriele Ferzetti (1925–2015), actor
- Alessia Filippi (* 1987), swimmer
- Ettore Fioravanti (* 1958), jazz percussionist and band leader
- Valentino Fioravanti (1764–1837), composer
- Roberto Fiore (* 1959), politician (neo-fascist)
- Ernesto de Fiori (1884–1945), Austrian sculptor, painter and draftsman
- Valerio Fiori (* 1969), football player and coach
- Fabio Firmani (* 1978), football player
- Giancarlo Fisichella (* 1973), racing car driver
- Alessandro Florenzi (* 1991), football player
- Luciano Floridi (* 1964), philosopher
- Alessio Foconi (* 1989), fencer
- Enrica Follieri (1926-1999), Byzantinist
- Marcello Fondato (1924–2008), film director and screenwriter
- Sepp Forcher (* 1930), Austrian radio and television presenter
- Luigi Forino (1868–1936), Italian-Argentine cellist and music teacher
- Simone Forte (* 1996), athlete
- Alessandro Franchi (1819–1878), Cardinal Secretary of State
- Bruno Francisci († 1989), automobile and motorcycle racing driver
- Marisa Del Frate (1931–2015), singer and actress
- Candido Maria Frattini (1767–1821), Curia Bishop
- Franco Frattini (* 1957), politician and EU commissioner
- Marco Frisina (* 1954), clergyman and composer of film scores
- Massimiliano Fuksas (* 1944), architect and designer
G
- Caterina Gabrielli (1730–1796), famous opera singer (soprano)
- Francesco Gabrieli (1904–1996), Arabist and Orientalist
- Giulio Gabrielli the Elder (1603–1677), bishop and cardinal
- Enrico Pietro Galeazzi (1896–1986), architect
- Luigi Galimberti (1836–1896), Curia Cardinal of the Roman Catholic Church and diplomat of the Holy See
- Carlo Giorgio Garofalo (1886–1962), organist and composer
- Matteo Garrone (* 1968), film director and screenwriter
- Enrico Gasbarra (* 1962), politician
- Giulio Gaudini (1904–1948), foil and epee fencer
- Tony Gaudio (1883–1951), American cameraman of Italian descent
- Giuliano Gemma (1938-2013), actor
- Domenico Genovesi (1765-1835), Archbishop of the Curia
- Giuseppe Gentile (* 1943), athlete
- Artemisia Gentileschi (1593–1653), Baroque painter
- Paolo Gentiloni (* 1954), politician and foreign minister of Italy since 2014
- François Gérard (1770–1837), French portrait painter
- Gerino Gerini (1928–2013), automobile racing driver
- Fernando Germani (1906–1998), organist, composer and organ teacher
- Geta (189–211), Roman emperor from February 4, 211 to December 26, 211
- Pier Leone Ghezzi (1674–1755), painter
- Fabio Di Giannantonio (* 1998), motorcycle racer
- Francesco Gianni (1750-1822), improviser
- Giuseppe Giannini (* 1964), football player and coach
- Fabiola Gianotti (* 1960), experimental particle physicist
- Paolo Giobbe (1880–1972), cardinal of the Roman Catholic Church
- Leonardo Giordani (* 1977), racing cyclist
- Bruno Giordano (* 1956), football player and coach
- Domiziana Giordano (* 1959), artist and actress
- Raffaello Giovagnoli (1838–1915), writer and historian
- Giuseppe Girometti (1780–1851), gem cutter, stamp cutter, sculptor and medalist
- Ignazio Giunti (1941–1971), automobile racing driver
- Alberto Giustolisi (1928–1990), chess player
- Leda Gloria (1908–1997), actress
- Domenico Gnoli (1838–1915), writer, art historian and librarian
- Luigi Gottifredi (1595–1652), Order General
- Carlo Grano (1887–1976), cardinal of the Roman Catholic Church
- Gregory the Great (around 540–604), Pope from 590 to 604 and Doctor of the Church
- Gregory II (669-731), Pope from 715 to 731
- Ugo Gregoretti (1930–2019), documentary filmmaker, film director and screenwriter
- Francesco De Gregori (* 1951), Cantautore (songwriter)
- Gregorio della Suburra († around 1162), cardinal of the Roman Catholic Church
- Leandro Greco (* 1986), football player
- Francesca Gregorini (* 1968), Italian-American director, screenwriter and film producer
- Fabrizio Grillo (* 1987), football player
- Fabio Grosso (* 1977), football player
- Sabina Grzimek (* 1942), sculptor
- Ennio Guarnieri (1930–2019), cameraman
- Enrico Guazzoni (1876–1949), film director, set designer, screenwriter and film producer
- Monica Guerritore (born 1958), actress
- Vittorio Gui (1885–1975), composer and conductor
- Augusto Guidi (1838–1900), Archbishop, President of the Pontifical Diplomatic Academy
- Camillo Guidi (1853–1941), civil engineer
- Umberto Guidoni (* 1954), physicist, astronaut and member of the European Parliament
- Gaspar de Guzmán, Conde de Olivares (1587–1645), Spanish Prime Minister at the time of Philip IV.
H
- Günther Haseloff (1912–1990), German art historian, prehistorian and medieval archaeologist
- Nicola Francesco Haym (1678–1729), musician, composer and librettist
- Otto von Hessen (1937–1998), German early historian and medieval archaeologist
- Heinrich von Hessen-Kassel (1927–1999), German painter and stage designer, who used his Italian name Enrico d'Assia as an artist
- Vanessa Hessler (* 1988), photo model and actress
- Honorius III. (around 1148–1227), Pope from 1216 to 1227
- Honorius IV (around 1210–1287), Pope from 1285 to 1287
- Danny Huston (* 1962), American actor and film director
I.
- Immanuel ha-Romi (* around 1261; † around 1335), poet in Hebrew
- Franco Interlenghi (1931–2015), actor and film producer
J
- Domenico Maria Jacobini (1837–1900), cardinal to the Curia and diplomat of the Holy See
- Nathan ben Jechiel (around 1020–1106), Jewish scholar
- John VIII (* before 852; † 882), Pope from 872 to 882
- Alberto di Jorio (1884–1979), cardinal of the Roman Catholic Church
- Jovanotti (* 1966), singer, rapper
- Juan Carlos I (* 1938), King of Spain from 1975 to 2014
- Julius I († 352), Pope from 337 to 352
- Julius III. (1487–1555), Pope from 1550 to 1555
K
- Tony Kendall (1936–2009), film actor
- Gaetano Koch (1849–1910), architect of historicism
- Alessandro Kouzkin (* 1992), Russian-Italian racing driver
L.
- Vincenzo Labella (1925–2018), screenwriter, film producer and film director
- Vittorio Magnago Lampugnani (* 1951), architect, architectural theorist and historian
- Orazio Lancellotti (1571-1620), cardinal
- Stefano Landi (1587–1639), singer, conductor and composer
- Marcello Lante (presumably 1561 - 1652), bishop and cardinal
- Antonio Lante Montefeltro della Rovere (1737-1817), cardinal
- Lorenzo Lauri (1864–1941), Cardinal Curia of the Roman Catholic Church
- Clelia Laviosa (1928–1999), archaeologist and etrusologist
- Giovanni Battista Leni (1573–1627), bishop and cardinal
- Leo III. (around 750-816) was Pope from 795 to 816
- Leo VII († 939), Pope from 936 to 939
- Leo VIII († 965), Pope from 963 to 965
- Gianfranco Leoncini (1939-2019), football player
- Sergio Leone (1929–1989), film director
- Liberius († 366), Bishop of Rome from 352 to 366
- Roberto Lippi (1926–2011), racing car driver
- Fabio Liverani (* 1976), football player and coach
- Mario Liverani (* 1939), ancient orientalist
- Carlo Lizzani (1922–2013), film director, screenwriter and actor
- Franco Lo Cascio (* 1946), film director and pornographer
- Augusto Paolo Lojudice (* 1964), Archbishop of Siena-Colle di Val d'Elsa-Montalcino
- Francesca Lollobrigida (* 1991), inline speed skater and speed skater
- Martino Longhi the Younger (1602–1660), architect
- Sophia Loren (* 1934), film actress
- Enrico Lorenzetti (1911–1989), motorcycle racer
- Paolo Lorenzi (* 1981), tennis player
- Vittorio Lucarelli (1928-2008), fencer
- Lucius I († 254), Bishop of Rome from 253 to 254
- Louis VI. (1328–1364 / 65), Duke of (Upper) Bavaria and Margrave and first Elector of Brandenburg
- Giovanni Battista Lugari (1846–1914), Curia Cardinal of the Roman Catholic Church
- Wolfgang Lutz (* 1956), Austrian demographer and university professor
M.
- Federico Macheda (* 1991), football player
- Marianna Madia (* 1980), politician and since 2014 Minister for Administrative Reforms and Simplification
- Federico de Madrazo y Kuntz (1815–1894), Spanish painter and lithographer of the Romantic period
- Bernardino Maffei (1514–1553), cardinal
- Michele Maffei (* 1946), fencer
- Orazio Maffei (1580–1609), Archbishop of Chieti and Cardinal
- Raffaello Maffei (1451–1522), theologian and humanist
- Anna Magnani (1908–1973), actress
- Franca Magnani (1925-1996), journalist
- Ingeborg Magnussen (1856–1946), painter and writer
- Luciano Maiani (* 1941), physicist
- Latino Malabranca Orsini (around 1235 - 1294), cardinal
- Sonia Malavisi (* 1994), pole vaulter
- Teobert Maler (1842–1917), German-Austrian architect, civil engineer, photographer, discoverer and researcher of Mayan ruins
- Franco Maria Malfatti (1927–1991), politician
- Hortensia Mancini (1646–1699), mistress of the English King Charles II.
- Guido Mancini (1924–1963), entrepreneur and racing car driver
- Laura Mancini (1635 / 36–1657), Duchess of Mercœur
- Maria Mancini (1639–1715), mistress of the French king Louis XIV.
- Olympia Mancini (1639–1708), mistress of the French King Louis XIV and from 1657 Countess of Soissons
- Lionello Manfredonia (born 1956), football player
- Silvana Mangano (1930–1989), actress
- Massimo Manzi (* 1956), jazz musician
- Marcella (* around 325; † around 410), martyr of the Christian Church
- Andrea Marcelli (* 1962), jazz percussionist and composer
- Francesco Marchetti Selvaggiani (1871–1951), Curia Cardinal of the Roman Catholic Church
- Riccardo Marchiò (* 1955), Commander in Chief of the Allied Joint Force Command Brunssum
- Enrico Marconi (1792–1863), Italian-Polish architect
- Paolo Marella (1895–1984), Curia Cardinal of the Roman Catholic Church
- Margarita of Spain (* 1939), sister of the former Spanish king Juan Carlos I.
- Antonio Margheriti (1930–2002), film director
- Carlo Maria Mariani (* 1931), painter
- Maria Anna (1803–1884), Empress of Austria (1835–1848)
- Marie Louise (1870–1899), Princess of Parma and Princess of Bulgaria
- Maria Theresia (1870–1935), daughter of Prince Charles VI. Heinrich Ernst zu Löwenstein-Wertheim-Rosenberg and wife of the Portuguese pretender to the throne, Duke Miguel II of Braganza
- Maria Theresia (1803–1879), daughter of King Victor Emanuel I of Sardinia-Piedmont
- Pietro Marini (1793 / 1794–1863), cardinal
- Francesco Marmaggi (1876–1949), diplomat of the Holy See and Cardinal Curia of the Roman Catholic Church
- Francesca Marsaglia (* 1990), ski racer
- Matteo Marsaglia (* 1985), ski racer and sports soldier
- Alessandra Martines (* 1963), film actress
- Michela Marzano (* 1970), philosopher, university lecturer, author and politician
- Francesco Maselli (* 1930), film director and screenwriter
- Giulia Masotti , called “La Dori” or “Giulia Romana” (approx. 1650–1701), soprano and opera singer
- Lea Massari (born 1933), actress
- Massimo Massimi (1877–1954), Curia Cardinal of the Roman Catholic Church
- Vincentius Massoni (1808–1857), Roman Catholic Archbishop and Diplomat of the Holy See
- Chiara Mastalli (* 1984), actress
- Ruggero Mastroianni (1929–1996), film editor
- Luigi Matera (1820-1891), Roman Catholic Archbishop and Diplomat of the Holy See
- Alessandro Mattei (1744–1820), Archbishop of Ferrara and Cardinal Curia of the Roman Catholic Church
- Bruno Mattei (1931–2007), film director and film editor
- Girolamo Mattei (1547-1603), cardinal
- Orazio Mattei (1574–1622), Bishop of Gerace
- Orazio Mattei (1621-1688), cardinal
- Marco Mattiacci (* 1970), manager in the automotive industry and Formula 1 team boss at Scuderia Ferrari in 2014
- Massimo Mattioli (1943–2019), underground artist and draftsman
- Anna Mazzamauro (* 1938), actress and singer
- Carlo Mazzone (* 1937), football player and coach
- Joel McHale (* 1971), American actor and comedian
- Giovanni Battista Mellini (1405–1478), Bishop of Urbino and Cardinal
- Giorgia Meloni (* 1977), politician and journalist, from 2008 to 2011 Minister of Youth and Sports
- Giampaolo Menichelli (* 1938), football player
- Antonio Mennini (* 1947), diplomat of the Holy See
- Antonietta Meo (1930–1937), an Italian girl who was born in 2007 by Pope Benedict XVI. as the youngest person (except martyrs) to date, the “Heroic Virtue” was awarded as a preliminary stage to beatification
- Marisa Merlini (1923–2008), actress
- Raffaele Mertes (* 1956), cameraman, director, screenwriter and producer
- Maurizio Merli (1940–1989), actor
- Pietro Metastasio (1698–1782), poet and librettist
- Rodolphe Meyer de Schauensee (1901–1984), American ornithologist of Swiss origin
- Franco Micalizzi (* 1939), film composer
- Maurizio Micangeli (* 1944), automobile racing driver
- Michael of Greece (* 1939), the only child of the Greek Prince Christoph of Greece
- Nicola Michetti (* around 1680; † 1758/59), architect
- Savo Millini (1644-1701), cardinal
- Gianni Minervini (* 1966), swimmer
- Paolino Mingazzini (1895–1977), classical archaeologist
- Federico Moccia (* 1963), writer, film director and screenwriter
- Franco Modigliani (1918–2003), economist and Nobel Prize winner
- Federica Mogherini (* 1973), politician
- Benedetto Molli (1597–1657), architect
- Mario Monicelli (1915–2010), screenwriter and film director
- Elsa Morante (1912–1985), writer
- Alberto Moravia (1907–1990), writer
- Franco Morbidelli (* 1994), motorcycle racer
- Emiliano Moretti (* 1981), football player
- Mario Moretti (1912–2002), classical archaeologist and Etruscanologist
- Claudia Mori (* 1944), singer, actress, and producer; Wife of Adriano Celentano
- Carlo Luigi Morichini (1805–1879), Archbishop of Bologna and Cardinal of the Roman Catholic Church
- Gian Marco Moroni (* 1998), tennis player
- Ennio Morricone (1928–2020), composer and conductor
- Gabriele Muccino (* 1967), film director and screenwriter
- Donatus von Münstereifel (* around 140; † before 180), Roman military leader and Catholic saint
- Luigi Musso (1924–1958), racing car driver
- Alessandra Mussolini (* 1962), neo-fascist politician
- Ornella Muti (born 1955), actress
- Tiberio Muti (1574–1636), Bishop of Viterbo and Cardinal
N
- Armando Nannuzzi (1925-2001), cameraman
- Célestin Nanteuil (1813–1873), French painter, draftsman and illustrator
- Filippo Napoletano (around 1587-1629), painter
- Gregorio Naro (1581–1634), Bishop of Rieti and Cardinal
- Alessandro Nesta (* 1976), football player
- Antonio Nibby (1792–1839), archaeologist, topographer and university professor
- Marcus von Niebuhr (1817–1860), Cabinet Councilor to the Prussian King Friedrich Wilhelm IV.
- Nicholas I (820–867), Pope from 858 to 867
- Nicholas III (* between 1210 and 1220; † 1280), Pope from 1277 to 1280
- Carlo Nocella (1826–1908), Curia Cardinal of the Roman Catholic Church
- Paolo Maria Nocera (* 1985), racing driver
- Noemi (* 1982), singer
- Franziska Nori (* 1968), German-Italian art historian, curator and museum director
- Giuliano Nostini (1912-1983), fencer
- Renzo Nostini (1914-2005), fencer
O
- Claudio Olivieri (1934–2019), painter
- Delio Onnis (born 1948), Argentine football player
- Alberto Orlando (born 1938), football player
- Franciotto Orsini (1473–1534), cardinal of the Roman Catholic Church
- Fulvio Orsini (1529–1600), late humanist, antiquarian and librarian
- Alfredo Ottaviani (1890–1979), Curia Cardinal of the Roman Catholic Church
P
- Camillo Pacetti (1758–1827), sculptor
- Michelangelo Pacetti (1793–1865), painter
- Vincenzo Pacetti (1746-1820), sculptor
- Pier Carlo Padoan (* 1950), economist and politician, Minister of Finance since 2014
- Luca Paganini (* 1993), football player
- Anita Pallenberg (1942–2017), model, actress and fashion designer
- Vincenzo Pallotti (1795–1850), Catholic priest and founder of an order
- Massimo Pallottino (1909–1995), archaeologist
- Luciana Paluzzi (born 1937), actress
- Silvana Pampanini (1925–2016), actress
- Alessandra Panaro (1939–2019), actress
- Patrizia Panico (* 1975), soccer player
- Raniero Panzieri (1921-1964), Marxist
- Arvid Pardo (1914–1999), Maltese diplomat, schoolmaster and university professor
- Massimo Paris (* 1953), violinist, composer, conductor and university professor
- Ryan Paris (born 1953), musician
- Gianfranco Parolini (1925–2018), film director and screenwriter
- Paul V (1552–1621), Pope from 1605 to 1621
- Antonio Pellegrini (1812-1887), cardinal
- Lorenzo Pellegrini (* 1996), football player
- Luca Pellegrini (* 1999), football player
- Federico Peluso (* 1984), football player
- Francesco Pentini (1797–1869), cardinal and politician of the Papal States
- Jacopo Peri (1561–1633), composer
- Achille Perilli (* 1927), painter and graphic artist
- Casimir Pfyffer (1794–1875), first mayor of Lucerne and publicist
- Giorgio Pessina (1902–1977), fencer
- Antonio Luigi Piatti (1782–1841), Archbishop of the Curia
- Carlo Pietromarchi (* 1937), automobile racing driver
- Luigi Pintor (1925–2003), journalist, publicist and politician
- Luca Pirri (* 1973), automobile racing driver
- Emanuele Pirro (* 1962), automobile racing driver
- Pius XII. (1876–1958), Pope from 1939 to 1958
- Carlo Alberto Pizzini (1905–1981), composer and conductor
- Matteo Politano (* 1993), football player
- Marco Politi (* 1947), journalist and book author
- Alberto Pomeranz († after 2000), pianist, composer and music teacher
- Domenico Pompili (* 1963), Bishop of Rieti
- Józef Michał Poniatowski (1816–1873), Polish composer, singer and diplomat
- Giacomo della Porta (≈1532–1602), architect and sculptor
- Gaspard Poussin (1615–1675), landscape painter
- Andrea Prodan (born 1961), actor
- Titus Pullo (1st century BC), Centurion
- Massimo Pupilo (* 1969), fusion and improvisation musician
Q
- Francesco Quinn (1963-2011), American actor
R.
- Virginia Raggi (* 1978), lawyer and politician (M5S); Mayor of Rome since 2016
- Pietro Raimondi (1786–1853), composer and music teacher
- Eros Ramazzotti (* 1963), singer and musician
- Gianluca Ramazzotti (* 1970), actor and voice actor
- Catherine de Vivonne, Marquise de Rambouillet (1588–1665), French noblewoman, held a literary salon in the Hôtel de Rambouillet in Paris
- Alfredo Rampi (1975–1981) plunged into an artesian well, was found dead despite attempts to rescue it
- Claudio Ranieri (* 1951), football player and coach
- Ranieri Randaccio (* 1952), racing car driver
- Francesco Angelo Rapaccioli (1605–1657), cardinal, bishop of Terni
- Fausto Razzi (* 1932), composer
- Dagmar Reichardt (* 1961), German literary scholar and Romance philologist
- Anna Renzi , called "Romana" (approx. 1620 - after 1662), opera singer (soprano)
- Mario Revelli di Beaumont (1907–1985), motorcycle racer and vehicle designer
- Andrea Riccardi (* 1950), theologian and co-founder of the Sant'Egidio group
- Luciano Ricceri (1940–2020), film architect and costume designer
- Francesco Ricci Paracciani (1830–1894), Roman Catholic cardinal and archpriest of St. Peter's Basilica
- Paolo Ricciardi (* 1968), Roman Catholic clergyman, auxiliary bishop in Rome
- Francesca Ridgway (1936–2008), archaeologist and etrusologist
- Cola di Rienzo (1313–1354), politician and tribune
- Carlo Roberti (1605–1673), Archbishop and Cardinal
- Manlio Rocchetti (1943–2017), make-up artist (Oscar-winning), lecturer
- Ciriaco Rocci (1582–1651), Archbishop and Cardinal
- Ettore Roesler Franz (1845–1907), Italian painter of German descent
- Paolo Antonio Rolli (1687–1765), poet and librettist
- Roberto Ronca (1901–1977), Roman Catholic Bishop, Prelate of Pompei
- Flavio Roma (* 1974), football player
- Giulio Romano (1499–1546), painter, architect and builder
- Cesare Romiti (1923–2020), Managing Director of Fiat
- Rocco Ronzani (* 1978), Catholic theologian
- Aleandro Rosi (* 1987), football player
- Isabella Rossellini (born 1952), actress
- Roberto Rossellini (1906–1977), director
- Daniele De Rossi (born 1983), football player
- Giovanni Battista de Rossi (1822-1894), Christian archaeologist and epigraphist
- Tullio Rossi (1903–1997), architect
- Tullio Rossi (* 1948), racing cyclist
- Nunzio Rotondo (1924–2009), jazz trumpeter
- Massimo Rotundo (* 1955), comic artist
- Antonio Rozzi (* 1994), football player
- Bruno Rubeo (1946–2011), set designer
- Giorgio Rubino (* 1986), athlete
- Bartolomeo Ruspoli (1697–1741), cardinal
- Gianrico Ruzza (* 1963), Bishop of Civitavecchia-Tarquinia
S.
- Stefano Sabelli (* 1993), football player
- Giulio Cesare Sacchetti (1587–1663), Cardinal to the Curia
- Fabrizio Saccomanni (1942–2019), economist
- Carlo Alberto Salustri, called Trilussa (1871–1950), dialect poet and fabulous author
- Fausto Salvatori (1870–1929), writer and librettist
- Cesare Sambucetti (1838–1911), Roman Catholic Archbishop and Diplomat of the Holy See
- Rafael Sánchez Ferlosio (1927–2019), Spanish writer
- Mauro Sandreani (* 1954), soccer player and coach
- Gianni Sanjust (1934-2020), jazz musician
- Antonio Santacroce (1599–1641), Archbishop and Cardinal
- Marcello Santacroce (1619–1674), Bishop of Tivoli and cardinal
- Prospero Santacroce (1514–1589), cardinal
- Sante de Santis (1965–2016), cook, restaurateur, cookbook author and TV chef in Germany
- Giulio Aristide Sartorio (1860–1932), painter, illustrator, screenwriter and film director
- Giacomo Savelli (1523–1587), cardinal of the Roman Catholic Church
- Giulio Savelli (1574–1644), Archbishop of Salerno and Cardinal
- Giovanna von Savoyen (1907-2000), wife of the Bulgarian Tsar Boris III.
- Giovanni Battista Scaramelli (1687–1752), Jesuit, priest, preacher and writer of ascetic and mystical books
- Giorgio Scarlatti (1921–1990), racing car driver
- Pietro Filippo Scarlatti (1679–1750), composer, organist and choir director
- Furio Scarpelli (1919-2010), screenwriter
- Pietro Scarpini (1911–1997), pianist and music teacher
- Patrizia Scascitelli (* 1949), jazz musician
- Rudolf Schadow (1786–1822), German sculptor
- Elsa Schiaparelli (1890–1973), Italian-French fashion designer
- Marie von Schleinitz (1842–1912), Berlin salonière and Richard Wagner's patron
- Alfredo Ildefonso Schuster (1880–1954), Archbishop of Milan and Cardinal of the Roman Catholic Church
- Toti Scialoja (1914–1998), painter and writer
- Yvonne Sciò (* 1969), actress
- Bruno Scipioni (1934–2019), actor and voice actor
- Luca Scribani Rossi (* 1960), marksman
- Stefano Sebastiani (* 1942), racing car driver
- Andy Selva (* 1976), San Marino soccer player
- Paolo Selvadagi (* 1946), auxiliary bishop in Rome
- Domenico Serafini (1852–1918), Archbishop of Spoleto and Cardinal Curia of the Roman Catholic Church
- Jordi Serangeli (* 1971), prehistoric archaeologist
- Alessio Sestu (* 1983), football player
- Fabrizio Sferra (* 1959), jazz drummer
- Alessandro Sforza (1534–1581), Bishop of Parma and Cardinal
- Francesco Siacci (1839–1907), mathematician, ballistician and officer
- Sabrina Siani (* 1963), film actress
- Enzo Siciliano (1934-2006), writer and journalist
- Marguerite Sikabonyi (* 1982), actress
- Clara von Simson (1897–1983), natural scientist and German politician (FDP)
- Fernando Silva (* 1986), Brazilian swimmer
- Silvester IV. († 1111), antipope from 1105 to 1111 to Paschal II.
- Lorenzo De Silvestri (* 1988), football player
- Attilio Simonetti (1843–1925), Roman genre painter
- Giancarlo De Sisti (* 1943), football player and coach
- Bobby Solo (born 1945), singer
- Sergio Sollima (1921–2015), screenwriter and film director
- Cornelio Sommaruga (* 1932), Swiss lawyer, former President of the ICRC
- Alberto Sordi (1920–2003), film, television and theater actor as well as director, screenwriter and voice actor
- Alessandro Spada (1787–1843), cardinal
- Alessandro Specchi (1666–1729), Roman architect and graphic artist
- Luciano Spinosi (* 1950), football player and coach
- Ludovico Stanzani (1793–1872), architect and art collector in the Ukraine
- Giampietro Stocco (* 1961), writer and journalist
- Vittorio Storaro (* 1940), cameraman and Oscar winner
- Charles Edward Stuart (1720–1788), exiled heir to the throne of Great Britain and Ireland
- Henry Benedict Stuart (1725–1807), Curia Cardinal of the Roman Catholic Church and a Catholic pretender to the British royal title
- Kim Rossi Stuart (born 1969), film and stage actor; Film director
T
- Antonio Tajani (* 1953), politician
- Enrico Tamberlik (1820–1889), opera tenor
- Dario Tamburrano (* 1969), politician
- Domenico Tardini (1888–1961), Curia Cardinal of the Roman Catholic Church
- Mauro Tassotti (* 1960), soccer player and coach
- Tatiana of Rome (* between 222 and 235; † before 250), Christian martyr
- Scipione Tecchi (1854–1915), Curia Cardinal of the Roman Catholic Church
- Gianfranco Tedeschi , double bass player
- Danilo Terenzi (1956–1995), jazz musician
- Mario Theodoli (1601–1650), cardinal of the Roman Catholic Church
- Tiberius (* 42 BC; † 37 AD), Roman emperor from 14 to 37 AD.
- Robert Tikkanen (1888–1947), Finnish marksman and architect
- Aurelio Tiratelli (1842–1900), painter
- Tommaso Tittoni (1855-1931), diplomat, politician and from March 12 to 27, 1905 President of the Council of Ministers (Prime Minister)
- Titus (39–81), Roman Emperor from 79 to 81
- Sergio Tofano (1883–1973), comic book artist, writer, director, actor and make-up artist
- Vincenzo Tommasini (1878–1950), composer
- Aldo Tonti (1910–1988), cameraman
- Giulio Tonti (1844–1918), diplomat and cardinal curia of the Roman Catholic Church
- Mario Torelli (* 1937), archaeologist and etrusologist
- Rodolfo Torti (* 1947), comic artist
- Mario Tosi (* 1942), Italian-American cameraman
- Francesco Totti (* 1976), football player
- Lucia Traversa (* 1965), fencer
- Tito Trocchi (1864–1947), diplomat and Curia Archbishop of the Roman Catholic Church
- Licia Troisi (* 1980), fantasy writer
- Armando Trovajoli (1917–2013), pianist and film composer
U
- Federico Ughi (* 1972), jazz drummer
- Urban VII. (1521–1590), Pope in 1590
V
- Antonio Rossi Vaccari (1808–1874), Curia Bishop
- Josefina Vannini (1859–1911), religious sister, founder of the order and blessed
- Egidio Vagnozzi (1906–1980), cardinal
- Giuseppe Valadier (1762–1839), architect, town planner, archaeologist and goldsmith
- Lorenzo Valla (1405 / 07–1457), humanist and canon
- Andrea della Valle (1463-1534), cardinal
- Pietro della Valle (1586–1652), traveler and travel writer
- Massimo Vanni (born 1946), actor
- Walter Veltroni (* 1955), journalist and politician, Mayor of Rome (2001-2008)
- Antonello Venditti (* 1949), Cantautore (songwriter)
- Franco Venturi (1914–1994), historian, essayist and journalist
- Roberto Venturoni (1945–2011), painter
- Fabrizio Verospi (1571–1639), cardinal
- Girolamo Verospi (1599–1652), cardinal and bishop
- Edoardo Vesentini (1928–2020), mathematician and politician
- Giuseppe Maria Vespignani (1800–1865), Bishop of Orvieto
- Lucius Vorenus (1st century BC), Centurion
- Vigilius (around 500 - 555), Pope from 537 until June 7, 555
- Giovanni da Vigo (around 1450 - 1525), medic (15th / 16th century)
- Luca Antonio Virili (1569-1634), cardinal
- Fabrizio Violati (1935–2010), entrepreneur and racing car driver
- Carolina Visca (* 2000), javelin thrower
- Carlo Lodovico Visconti (1818-1894), archaeologist
- Ennio Quirino Visconti (1751–1818), archaeologist
- Filippo Aurelio Visconti (1754–1831), archaeologist
- Louis Visconti (1791-1853), French architect
- Mutio Vitelleschi (1563-1645), Order General
- Monica Vitti (born 1931), actress
- Matthias Theodor Vogt (* 1959), German cultural historian and author
- Milena Vukotic (born 1935), actress
W.
- John William Waterhouse (1849–1917), British painter belonging to the Pre-Raphaelite group
- Arthur Valerian Wellesley, 8th Duke of Wellington (1915-2014), British nobleman, brigadier and entrepreneur
- Lina Wertmüller (* 1928), film director
- William Frederick, Duke of Gloucester and Edinburgh (1776–1834), member of the British royal family
Z
- Giovanni Zamboni (* after 1650), composer
- Luigi Zampa (1905–1991), film director of neorealism
- Daniel Zampieri (* 1990), racing driver
- Carlo Zecchi (1903–1984), pianist, conductor and music teacher
- Francesco Saverio de Zelada (1717–1801), cardinal of the Roman Catholic Church
- Bruno Zevi (1918–2000), architect, architectural historian, author and university professor
- Antonio Zugarelli (born 1950), tennis player
- Matteo Maria Zuppi (* 1955), Catholic clergyman, Archbishop of Bologna and Cardinal