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Is
Isa
- Isa (* 1998), Swedish singer and songwriter
- Isa Agha († 1875), Yazidi head
- Isa I (1848–1932), ruler of Bahrain
- Isa ibn Nasturus († 997), chief minister of the Fatimid caliph al-Aziz (994–996)
- Isa, Dawid († 1882), Yazidi chief in Sinjar
- Isa, Dolkun (* 1967), Uighur-German politician and activist
- Isa, Harun (* 1969), Yugoslav football player
- Isa, Hidenori (* 1976), Japanese biathlete
- Isa, Kōhei (* 1991), Japanese football player
- Isa-tai , Comanche warrior and medicine man
- Isaac Mullen, Pedro (* 1985), Cuban wrestler
- Isaac, Alfred (1888–1956), German economist
- Isaac, Augie (* 2000), American actor
- Isaac, Benjamin (* 1945), Israeli ancient historian
- Isaac, Bobby (1932–1977), American NASCAR racing driver and champion
- Isaac, Glynn (1937–1985), South African paleoanthropologist
- Isaac, Heinrich († 1517), Franco-Flemish composer and singer of the Renaissance
- Isaac, Ismaël (* 1966), Ivorian singer (Côte d'Ivoire)
- Isaac, James (1960–2012), American film director
- Isaac, Jeffrey (* 1956), American painter and video artist
- Isaac, Jonathan (* 1997), American basketball player
- Isaac, Jules (1877–1963), French historian
- Isaac, Leandro (* 1953), East Timorese politician
- Isaac, Oscar (* 1979), American film and stage actor
- Isaac, Rhys (1937-2010), South African historian
- Isaac, Robert M. (1928–2008), American politician
- Isaac, Vernon (1913-1999), American jazz musician
- Isaac-Bénédic, Armand (1875–1962), French curler
- Isaachsen, Olaf (1835-1893), Norwegian painter
- Isaacius , Byzantine Exarch of Ravenna
- Isaacks, Heinrich (* 1985), Namibian soccer player
- Isaacks, Levie (* 1946), American cameraman
- Isaacs, Alick (1921-1967) British virologist and immunologist
- Isaacs, Brian (* 1967), Namibian football player and coach
- Isaacs, Gardeo (* 1998), South African sprinter
- Isaacs, Gerald, 2nd Marquess of Reading (1889–1960), British lawyer and politician
- Isaacs, Gregory (1951-2010), Jamaican reggae singer
- Isaacs, Harold (1910–1986), American journalist and political scientist
- Isaacs, Harry (1902–1973), English pianist and music teacher
- Isaacs, Henry (1830-1909) English politician
- Isaacs, Hyam (1927-2003), South African physiologist
- Isaacs, I. Martin (* 1940), American mathematician
- Isaacs, Ike (1919-1996), British jazz guitarist
- Isaacs, Ike (1923–1981), American jazz bassist
- Isaacs, Isaac (1855–1948), Chief Justice and Governor General of Australia
- Isaacs, Jason (born 1963), British actor
- Isaacs, Jorge (1837–1895), Colombian writer and liberal politician
- Isaacs, Rufus (1914–1977), American mathematician
- Isaacs, Rufus, 1st Marquess of Reading (1860–1935), British politician and lawyer
- Isaacs, Sam (1845-1920), Australian Aboriginal
- Isaacs, Simon, 4th Marquess of Reading (born 1942), British aristocrat, banker and philanthropist
- Isaacs, Stella, Marchioness of Reading (1894–1971), British nobleman
- Isaacs, Susie (* 1946), American poker player
- Isaacsohn, Siegfried (1845–1882), German educator, historian and teacher
- Isaacson von Newfort, Heinrich (1813-1896), Austrian officer
- Isaacson, Harunaga (* 1965), Japanese Indologist
- Isaacson, Jeff (* 1983), American curler
- Isaacson, Walter (1910–1999), German educator and emigrant, teacher at rural school homes
- Isaacson, Walter (* 1952), American writer
- Isaac , Patriarch of Jerusalem
- Isaac , Count of Cambrai
- Isaac († 1429), Negus Negest (Emperor) of Ethiopia
- Isaak Albalag , Jewish philosopher
- Isaak from Aachen , German-Jewish interpreter and negotiator for Harun al Raschid
- Isaac ben Eleazar , Jewish scribe
- Isaac ben Eleazar ha-Levi , rabbi and Talmud scholar
- Isaak ben Eliakum , Yiddish writer
- Isaak ben Josef ibn Polegar , Spanish-Jewish scholar
- Isaak ben Meïr from Düren , German rabbi and dean
- Isaac ben Melchizedek of Siponto , Italian rabbi
- Isaac ben Mose , Jewish scholar
- Isaac ben Mose Hallevi Profiat Duran , Jewish scholar
- Isaak ben Sheschet (1326–1408), Jewish scholar
- Isaac the blind , Jewish scholar, Kabbalist
- Isaac the Great († 439), Armenian clergyman, saint, Catholicos (or patriarch) of Armenia
- Isaak Dukas Batatzes († 1261), Byzantine aristocrat, brother of Emperor John III.
- Isaac I († 1061), Byzantine Emperor (1057-1059)
- Isaak ibn Latif , Spanish-Jewish religious philosopher
- Isaac II (1155–1204), Byzantine emperor
- Isaak Komnenos , Byzantine usurper against Emperor Isaac II.
- Isaak Komnenus , Byzantine general and Sebastocrator, brother of Emperor Alexios I.
- Isaak Komnenus , Byzantine prince, son of Emperor Alexios I.
- Isaak Komnenus , Byzantine prince and pretender to the throne, son of Emperor John II.
- Isaak Komnenos , Emperor of Cyprus
- Isaak Komnenos Batatzes († 1196), Byzantine aristocrat, son-in-law of Emperor Alexios III.
- Isaak Laskaris , Byzantine Sebastocrator, brother of Emperor Theodor I and usurper against Emperor John III.
- Isaak Nestongos , Byzantine aristocrat, conspirator against Emperor John III.
- Isaac of Antioch († 460), Christian theologian of antiquity
- Isaac of Dalmatia († 396), Byzantine monk, prophet and saint
- Isaak von Montjoie , German Jewish entrepreneur and community leader
- Isaac of Nineveh , bishop, saint, ascetic, mystic
- Isaac von Stella († 1178), Cistercian abbot and writer
- Isaak, Aaron (1730–1816), founder of the Jewish community in Stockholm
- Isaak, Chris (* 1956), American singer and film actor
- Isaak, Dawit (* 1964), Swedish journalist
- Isaak, Dirk , Namibian traditional guide
- Isaak, Felix (* 1989), German volleyball player
- Isaak, Tassos (1972–1996), Cypriot protester, victim of the Cyprus conflict
- Isaak, Zhenja (* 1985), German actor
- Isaakowa, Michalina (1880–1937), Polish entomologist
- Isaakson, Eduard (1841–1913), German businessman and politician, MdHB
- Isaaz, Alice (* 1991), French actress
- Isabeau († 1435), Queen of France
- Isabekjan, Edouard (1914–2007), Armenian-Soviet painter and graphic artist
- Isabel de Clare , Anglo-Scottish noblewoman
- Isabel de Portugal (1397–1471), daughter of John I of Portugal and wife of Philip III. of Burgundy
- Isabel of Gloucester († 1217), Countess of Gloucester; Wife of the future King Johann Ohneland
- Isabel of Portugal (1432–1455), Queen of Portugal
- Isabel of Spain (1821–1897), Spanish infanta
- Isabella († 1453), Duchess of Lorraine (1431–1453)
- Isabella Bruce († 1358), Queen of Norway
- Isabella Clara Eugenia of Spain (1566–1633), Spanish infanta and governor of the Spanish Netherlands
- Isabella Clara of Austria (1629–1685), Archduchess of Austria, by marriage Duchess of Mantua
- Isabella de Coucy , wife of Enguerrand VII. De Coucy
- Isabella d'Este (1474–1539), Margravine of Mantua, art collector of the Italian Renaissance
- Isabella I (1170–1205), Queen of Jerusalem
- Isabella I (1451–1504), Queen of Castile
- Isabella II (1212–1228), Queen of Jerusalem
- Isabella II (1830–1904), Queen of Spain (1833–1868)
- Isabella Maria of Portugal (1801–1876), Portuguese princess, regent of Portugal
- Isabella of Angoulême († 1246), Countess of Angoulême and Queen of England
- Isabella of Aragón († 1271), Queen of France
- Isabella of Aragón (1470–1524), Duchess of Milan
- Isabella of Aragon and Castile (1470–1498), Princess of Aragon and Castile, Queen of Portugal
- Isabella of Armenia , daughter of the Armenian King Leo III.
- Isabella of Armenia († 1252), Queen of Armenia
- Isabella von Bayern (1863–1924), daughter of Prince Adalbert Wilhelm von Bayern and Amalia de Bourbón
- Isabella of Beirut († 1282), Queen of Cyprus and Mistress of Beirut
- Isabella von Braganza (1402–1465), daughter of Alfons von Braganza and Beatriz Pereira de Alvim
- Isabella of Brazil (1846–1921), Crown Princess of Brazil
- Isabella von Brienne († 1360), Countess of Brienne and Lecce, titular duchess of Athens
- Isabella of Burgundy , Roman-German queen
- Isabella of England (1214–1241), English princess, Holy Roman Empress
- Isabella of France (1242–1271), Queen of Navarre
- Isabella of Hainaut († 1190), Queen of France
- Isabella of Ibelin (1241–1324), by marriage queen of Cyprus and Jerusalem
- Isabella of Castile (1283–1328), Queen of Aragon and Duchess of Brittany
- Isabella of Castile († 1392), Spanish nobleman and by marriage Duchess of York
- Isabella von Mar († 1296), first wife of Robert the Bruce
- Isabella of Austria (1501–1526), Queen of Denmark
- Isabella of Austria-Teschen (1888–1973), Archduchess of Austria-Teschen
- Isabella of Portugal († 1496), mother of Isabella I the Catholic
- Isabella of Portugal (1503–1539), wife of Charles V.
- Isabella of Scotland , Scottish King's daughter
- Isabella of Spain (1851–1931), Spanish princess from the Bourbon family
- Isabella of Toron , Princess of Lesser Armenia, titular mistress of Toron and Oultrejordain
- Isabella of Cyprus († 1264), daughter of Hugo I, regent of Cyprus
- Isabella, Countess of Fife , Scottish magnate
- Isabella, Tony (* 1951), American comic book author
- Isabelle († 1428), Countess of Foix
- Isabelle , American wolf child
- Isabelle de France († 1269), founder of the monastery
- Isabelle de France († 1358), princess of France and wife of King Edward II.
- Isabelle de Valois (1389–1409), Princess of France, daughter of King Charles VI.
- Isabelle de Villehardouin (1263–1312), princess of Achaia
- Isabelle, Ana (* 1986), Puerto Rican singer, dancer and actress
- Isabelle, Katharine (* 1981), Canadian actress
- Isabey, Eugène (1803-1886) French painter
- Isabey, Jean-Baptiste (1767–1855) French painter
- Isac, Lidia (* 1993), Moldovan pop singer
- Isachsen, Gunnerius Ingvald (1868–1939), Norwegian polar explorer
- Isacker, Piet van , Belgian physicist
- Isacks, Jacob C. (1767-1835), American politician
- Isacson, Leo (1910–1996), American lawyer and politician
- Isacsson, Arne (1917–2010), Swedish painter and art educator
- Isael (* 1988), Brazilian soccer player
- Isaev, Kristina (* 2001), German figure skater
- Isagoras , politician in Athens
- Isah, Musa (* 2000), Bahraini sprinter
- Isai, Hekuran (1933–2008), Albanian communist politician
- Isaia da Pisa , Italian sculptor
- Isaiah the Serb , Serbian monk
- Isăilă, Daniel (* 1972), Romanian football player and coach
- Isăilă, Ion-Ilarion (* 1953), Romanian painter
- Isailović, Bojan (* 1980), Serbian football player
- Isailović, Ivana (* 1986), Serbian volleyball player
- Isailović, Nikola (* 1986), Serbian handball player
- Isaios , Attic orator
- Isak ben Mordechai , Jewish scribe
- Ísak Bergmann Jóhannesson (* 2003), Icelandic football player
- Isak, Alexander (* 1999), Swedish football player
- Isaka, Mito (* 1976), Japanese soccer player
- Isaka, Teppei (* 1974), Japanese football player
- Isakiewicz, Edith (* 1907), Austrian-British athlete
- Isakov, Gregory Alan (* 1979), American singer-songwriter
- Isaković, Antonije (1923–2002), Yugoslav or Serbian writer and politician
- Isaković, Mile (* 1958), Yugoslav-Serbian handball player and coach
- Isakovič, Sara (* 1988), Slovenian swimmer
- Isakow, Sapar Dschumakadirowitsch (* 1977), Kyrgyz statesman, Prime Minister of Kyrgyzstan (2017-2018)
- Isakower, Otto (1899–1972), American psychiatrist and psychoanalyst
- Isakowitz, Melanie (* 1980), German actress, voice-over and dubbing artist
- Isaksen, Ella Marie Hætta (* 1998), Norwegian-Sami singer and joiker
- Isaksen, Finn T. (1924–1987), Norwegian politician (Senterpartiet) and manager
- Isaksen, Gustav (* 2001), Danish football player
- Isaksen, Ingvild (* 1989), Norwegian soccer player
- Isaksen, Jógvan (* 1950), Faroese writer
- Isaksen, Kjersti (* 1986), Norwegian biathlete
- Isaksen, Lassin (* 1961), Faroese football referee
- Isaksen, Torbjørn Røe (* 1978), Norwegian conservative politician
- Ísakson, Finnbogi (1943–2005), Faroese journalist, writer and politician for the republican Tjóðveldisflokkurin
- Isakson, Jane (born 1965), Canadian biathlete
- Isakson, Johnny (* 1944), American politician
- Isaksson, Andreas (* 1981), Swedish football goalkeeper
- Isaksson, Kjell (* 1948), Swedish pole vaulter
- Isaksson, Preben (1943–2008), Danish track cyclist
- Isaksson, Sara (* 1971), Swedish jazz and pop singer
- Isaksson, Staffan (* 1952), Swedish football player and coach
- Isaksson, Ulf (1954–2003), Swedish ice hockey player
- Isaksson, Ulla (1916–2000), Swedish author and screenwriter
- Isakstuen, Monica (* 1976), Norwegian writer
- Isaman, Roy Maurice (1917–1988), American naval officer
- Isambert, François-André (1792–1857), French lawyer and politician
- ʿIsāmī, al- (1639–1699), Muslim historian, scholar and poet of Shafi'i teaching
- Isamitt, Carlos (1887–1974), Chilean composer, painter and university professor
- Isangrim († 941), Bishop of Regensburg
- Isani, Claudio (1941–2001), German cultural journalist and author
- Isao, Nakauchi (1922–2005), Japanese entrepreneur and philanthropist
- Isar (* 1983), German-Turkish rapper and producer
- Isar-Damu , ruler of Ebla
- Isara, Bodin (* 1990), Thai badminton player
- Isard, Walter (1919-2010), American economist
- Isărescu, Andreea (* 1984), Romanian gymnast
- Isărescu, Mugur (* 1949), Romanian politician
- Isariya Marom (* 1995), Thai soccer player
- Isarnus von Fontiano († 1310), Archbishop of Riga, Archbishop of Lund and Archbishop of Salerno
- Isasi, Andrés (1890–1940), Basque-Spanish composer
- Isasi, Iñaki (* 1977), Spanish cyclist
- Isasi, Joel (* 1967), Cuban athlete
- Isasi-Isasmendi, Antonio (1927–2017), Spanish film director, screenwriter, film editor, and film producer
- Isaszegi, Róbert (* 1965), Hungarian boxer
- Isatitsch, Bert (1911–1994), Austrian tobogganing official
- Isau, Ralf (* 1956), German writer
- Isava Fonseca, Flor (1921–2020), Venezuelan equestrian, tennis and golf player and IOC member
- Isawa, Taka (1933–1997), Japanese writer
- Isay, Ernst (1880–1943), German lawyer
- Isay, Hermann (1873–1938), German lawyer
- Isay, Richard (1934–2012), American psychiatrist
- Isay, Rudolf (1886–1956), German lawyer, patent attorney and antitrust expert
- Isayama, Hajime (* 1986), Japanese mangaka
- İsayev, Əli (* 1983), Azerbaijani and Russian wrestler
- İsayev, Arif (* 1985), Azerbaijani football player
- İsayev, Radik (* 1989), Azerbaijani Taekwondoin
Isb
- Isbary, Gerhard (1909–1968), German spatial planner
- Isbary, Rudolf von (1827–1892), Austrian textile industrialist, member of the Reichsrat and President of the Vienna Chamber of Commerce
- Isbej, Verónica (* 1976), Chilean biathlete
- Isbel, Ursula (* 1942), German writer and translator
- Isbell, Cecil (1915–1985) American football player and coach
- Isbell, Jason (* 1979), American southern rock musician
- Isbell, John (1930-2005), American mathematician
- Isberg, Jürgen (* 1928), German handball world champion
- Isberg, Paul (1882–1955), Swedish sailor
- Isberg, Sophia (1819–1875), Swedish artist
- Isbert, Adolf (1858–1938), German automotive expert and functionary
- Isbert, August (1856–1950), Prussian general of the infantry
- Isbert, Christian (1929–1986), German life coach, graphologist, astrologer, editor and translator
- Isbert, Jakob (1808–1881), ducal Nassau bailiff and magistrate, later royal Prussian court judge and appellate judge
- Isbert, Jakob (1846–1888), Roman Catholic priest in the Trier Kulturkampf
- Isbert, José (1886–1966), Spanish actor
- Isbert, Karl (1864–1946), Prussian major general
- Isbert, Marion (* 1964), German soccer player
- Isbert, Otto Albrecht (1901–1986), German yoga teacher and yoga writer
- Isbert, Tony (born 1950), Spanish actor
- Isbert, Volkan (* 1988), German actor
- Išbi-Erra , King of Sumer and founder of the Isin dynasty
- Isbin, Sharon (* 1956), American classical guitarist
- Isbister, Brad (born 1977), Canadian ice hockey player and coach
- Isbrücker, Isaäc (* 1944), Dutch ichthyologist
Isc
- İşcan, Elit (* 1994), Turkish actress
- İşcan, Eray (* 1991), Turkish soccer goalkeeper
- Ish Schalom, Mordechai (1901–1991), Israeli politician
- Ish-Boscheth , son of King Saul
- Ischajew, Viktor Ivanovich (* 1948), Russian politician
- Ischakow, Margub Timergalijewitsch (1923–1992), Tatar Major General of the Chinese People's Liberation Army
- Ischangulyjewa, Merdschen (* 1988), Kazakh hurdler of Turkmen origin
- Ischdonat, Daniel (* 1976), German soccer goalkeeper
- Ischer, Theophil (1885–1954), Swiss teacher and prehistoric
- Ischer, Yvan (* 1961), Swiss jazz musician (tenor saxophone, also alto and soprano saxophone) and jazz journalist
- Ischi, Takeo (* 1947), Japanese singer and yodeler
- Ischimowa, Alexandra Ossipowna (1805–1881), Russian author and translator for children and young people
- Ischinger, Barbara (* 1949), German scientist and OECD diplomat
- Ischinger, Wolfgang (* 1946), German diplomat
- Ischirkow, Anastas (1868–1937), Bulgarian geographer
- Ischlinski, Alexander Juljewitsch (1913–2003), Soviet and Russian mechanic and mathematician
- Ischmametjew, Alexei Viktorovich (* 1988), Russian ice hockey player
- Ischmuratow, Airat Rafailowitsch (* 1973), Russian-Canadian composer, conductor and klezmer clarinetist
- Ischmuratowa, Svetlana Irekovna (* 1972), Russian biathlete
- Ischo-Jab III. († 659), Patriarch of the Assyrian Church of the East
- Ischowa, Jekaterina Jurjewna (* 1989), Russian medium and long-distance runner
- Ishchenko, Mychajlo (* 1950), Soviet handball player
- Ischtschenko, Natalja Sergejewna (* 1986), Russian synchronized swimmer
- Ishchenko, Pavlo (* 1992), Ukrainian boxer
- Ishchenko, Volodymyr , Ukrainian sociologist
- İşçiler, Batuhan (* 1995), Turkish soccer player
- Isco (* 1992), Spanish soccer player
- Iscove, Robert (* 1947), Canadian film director and film producer
Isd
- Isdal, Arve (* 1977), Norwegian guitarist
- Isdal woman († 1970), unknown female fatality in Norway
- Isdell, Edward Neville (born 1944) Northern Irish businessman and CEO of the Coca-Cola Company
- Isdryk, Jurij (* 1962), Ukrainian writer, cultural scientist and magazine editor
Ise
- Ise († 938), mistress and poet
- Ise, Kō (* 2002), Japanese football player
- Isebrand, Wulf († 1506), fought in 1500 in the Battle of Hemmingstedt
- Isecke, Regina (1953–2015), German wheelchair tennis player
- Iseda, Tetsuji (* 1968), Japanese philosopher
- Isegawa, Moses (* 1963), Ugandan writer
- Iseke, Hermann (1856–1907), German poet
- Isele, Eugen (1902–1992), Swiss legal scholar
- Isele, Hellmut Georg (1902–1987), German legal scholar
- Isele, Klaus (* 1960), German publisher, editor and publicist
- Isele, Leo (* 1907), German gymnast
- Iseler, Dieter (* 1937), German architect and politician (SPD), MdHB
- Iseli, Christian (* 1957), Swiss filmmaker
- Iseli, Rolf (* 1934), Swiss painter and graphic artist
- Iselin, Christoph (1869–1949), pioneer in Swiss skiing history
- Iselin, Heinrich (1888–1955), Swiss officer
- Iselin, Isaak (1728–1782), Swiss journalistic philosopher of history during the Enlightenment
- Iselin, Jakob Christoph (1681–1737), Swiss theologian, historian and lexicographer
- Iselin, Johann Rudolf (1705–1779), Swiss lawyer, historian and editor
- Iselin, Pauline (1876-1946), American golfer
- Iselin-Sarasin, Isaak (1851–1930), Swiss lawyer, politician and officer
- Isella, Dante (1922–2007), Italian Romance studies and literary scholar
- Isella, Edoardo (* 1980), Mexican soccer player
- Iselstein, Franz Wilhelm von († 1777), Prussian lieutenant colonel and chief of the Königsberger Land Regiment
- Iseman, Madison (born 1997), American actress
- Isemann, Bernd (1881–1967), German writer
- Isemann, Till (* 1996), German basketball player
- Isembart († 852), Frankish nobleman, Count of Barcelona
- Isemborghs, Hendrik (1914–1973), Belgian football player
- Isemeyer, Manfred (* 1948), German political scientist, publicist and humanist
- Isenbart, August (1876–1940), German Imperial Judge
- Isenbart, Hans-Heinrich (1923–2011), German moderator and horse specialist
- Isenbart, Jürgen (1943–2015), German multi-instrumentalist, percussionist, performance artist and comedian
- Isenbeck, Karl (1904–1945), German plant breeding scientist
- Isenbeck, Ludwig (1882–1958), German sculptor
- Isenberg, Beta (1846–1933), German patron for church, social and cultural purposes
- Isenberg, Gabriele (* 1943), German historian and medieval archaeologist
- Isenberg, Gerhard (1902–1982), German economist, spatial planner and regional planner
- Isenberg, Herbert (* 1930), German painter
- Isenberg, Horst (* 1937), German text linguist and Hispanist
- Isenberg, Johann von († 1484), auxiliary bishop in Speyer, Minorit
- Isenberg, Jürgen (* 1971), German biathlete
- Isenberg, Karl (1906–1977), German politician (SPD), MdL
- Isenberg, Nancy , American historian
- Isenberg, Paul (1837–1903), German sugar manufacturer
- Isenberg, Sally (1889–1961), German banker
- Isenberg, Thomas (* 1967), German politician (SPD), MdA
- Isenbiehl, Johannes Lorenz (1744-1818), German theologian
- Isenbort, Gregor (* 1970), German economic and social historian and philosopher
- Isenbrant, Adriaen († 1551), Dutch painter
- Isenbügel, Felix (* 1986), German theater and television actor
- Isenbügel, Günther (1922–1996), German sports reporter and motor sportsman
- Isenburg and Büdingen, Friedrich Wilhelm zu (1730–1804), lieutenant general and chamberlain from Bavaria
- Isenburg and Büdingen, Viktor Alexander zu (1802–1843), civil registrar
- Isenburg and Büdingen, Wolfgang Ernst II zu (1735–1803), German prince
- Isenburg and Büdingen, Wolfgang Ernst III. zu (1798–1866), member of the Grand Duchy and Electorate of Hesse, member of the state parliament
- Isenburg, Anna von (1460–1522), German nobleman
- Isenburg, Arnold II. Von († 1259), Archbishop of Trier
- Isenburg, Bonizeth von , abbess at Freckenhorst Abbey
- Isenburg, Diether von (1412–1482), German clergyman, Archbishop of Mainz (1459–1462 and 1475–1482)
- Isenburg, Helene Elisabeth von (1900–1974), President of the Silent Help for Prisoners of War Association
- Isenburg, Hugo , German publisher
- Isenburg, Wilhelm Karl von (1903–1956), German genealogist
- Isenburg-Birstein, Christian Ludwig von (1710–1791), Hesse-Kassel general and German prince
- Isenburg-Birstein, Franz-Joseph zu (1869–1939), German nobleman, landlord and head of the Isenburg-Birstein house
- Isenburg-Birstein, Johann Casimir von (1715–1759), German army leader
- Isenburg-Birstein, Karl zu (1838–1899), German nobleman, landlord and head of the Isenburg-Birstein house
- Isenburg-Büdingen zu Ronneburg, Anton von (1501–1560), Count
- Isenburg-Büdingen, Johann Ernst I von (1625–1673), founder of the Büdinger line of the Isenburg family
- Isenburg-Büdingen, Wolfgang Ernst I von (1560–1633), Count of Isenburg and Burgrave of Gelnhausen
- Isenburger, Eric (1902–1994), German painter
- Isendahl, Walter , German naval officer
- Isendahl, Walther (1877–1950), German engineer and specialist writer for motor vehicles and automotive engineering
- Isene, Kristi Anna , Norwegian opera singer (soprano)
- Isenegger, Samuel (1899–1964), Swiss study composer
- Isenfels, Paul (1888–1974), German actor, writer and photographer
- Isenflamm, Heinrich Friedrich (1771–1828), German physician and university professor
- Isenflamm, Jacob Friedrich (1726–1793), German physician and university professor
- Isengard , noblewoman
- Isengwe, Christopher (* 1976), Tanzanian marathon runner
- Isenhofer von Waldshut , author of a blacksmith's against the Confederates
- Isenkrahe, Caspar (1844–1921), German mathematician, physicist and Catholic natural philosopher
- Isenmann, Anton , Prismeller stonemasons and foremen
- Isenmann, Caspar , painter and engraver
- Isenmann, Eberhard (* 1944), German historian
- Isenmann, Eduard (1860–1932), German politician (center), MdR
- Isenmann, Hermann (1908–1991), German sculptor, metal caster and restorer
- Isenmann, Johann († 1574), Lutheran theologian and reformer
- Isenrath, Hans Paul (* 1936), German sculptor and university professor
- Isenrath, Jacob (1879–1951), German police chief and politician (center)
- Isenring, Johann Baptist (1796–1860), Swiss landscape painter and Daguerre typist
- Isenschmid, Andreas (* 1952), Swiss journalist and literary critic
- Isenschmid, Josef (1908–2009), Swiss politician (Conservative People's Party)
- Isensee, Ada (* 1944), German painter
- Isensee, August Ludwig Christian (1743-1824), German hymn poet
- Isensee, Josef (* 1937), German constitutional lawyer
- Isensee, Rik , American author and therapist
- Isensee, Willy , German politician (KPD, SED), MdL
- Isenstein, Kurt Harald (1898–1980), German sculptor and art teacher
- Isenta, Ellen (1885–1959), German actress
- Isentrud von Hörselgau , wife in the entourage of Elisabeth of Thuringia, witness in their canonization process
- Isepp, Sebastian (1884–1954), Austrian painter
- Iser, Dorothea (* 1946), German writer
- Iser, Gabriel Hubert (1826–1907), German Imperial Judge
- Iser, Iosif (1881–1958), Romanian painter
- Iser, Wolfgang (1926–2007), German English and literary scholar
- Iserbyt, Eli (* 1997), Belgian racing cyclist
- İşeri, Doğa (* 1992), Turkish soccer player
- Iserles, Arieh (* 1947), Israeli mathematician
- Iserloh, Erwin (1915–1996), Catholic church historian
- Iserlohe, Klaus (1928–2011), German sculptor of sacred art
- Iserlohe, Ulrich (* 1946), German politician (SPD), MdL
- Isermann, Gerhard (1931–2015), German Lutheran theologian, publicist and author
- Isermann, Heinz (* 1941), German economist
- Isermann, Ludolph (* 1882), German manufacturer
- Isermann, Maike (* 1963), German biologist and qualified research assistant at the University of Bremen
- Isermann, Rolf (* 1938), German engineer, professor of control engineering and scientist for mechatronics
- Isermeyer, Christian Adolf (1908–2001), German art historian
- Isermeyer, Folkhard (* 1958), German agricultural economist
- Isern, Fernando (* 1958), Cuban clergyman, emeritus bishop of Pueblo
- Isernhagen, Gustav (* 1937), German politician (CDU), MdL
- Isernhagen, Hans (1897–1960), German politician (DP), MdL
- Isernhagen, Hartwig (* 1940), German Anglicist
- Isernhagen, Peter († 1664), merchant and councilor of the Hanseatic city of Lübeck
- Isert, Bernd (1951–2017), German graduate engineer, coach, trainer and author
- Isert, Paul Erdmann (1756–1789), German botanist and zoologist
- Iset , second or third daughter of Amenhotep III. and his Great Royal Wife Teje; Sister of Akhenaten (Amenhotep IV)
- Iset , daughter of Ramses VI .; Consort of Amun
- Isett, Philip (* 1986), American mathematician
- Isettahemdjert , wife of the Egyptian pharaoh Ramses III.
- Isezaki, Jun (* 1936), Japanese artisan and living national treasure
- Isezaki, Kenji (* 1957), Japanese development worker, UN worker and university professor
Isf
- Isfahani, Abu Turab (1581–1662), Persian calligrapher
- Isfahani, Ali ibn Sahl († 919), Persian mystic
- Isfahani, Baba Shah († 1588), Iranian calligrapher and calligraphy teacher
- Isfahani, Mohammed Saleh , Iranian calligrapher
- Isfahani, Nur ad-Din Mohammed († 1683), Persian calligrapher
- Isfalt, Björn (1942–1997), Swedish musician and film composer
- Isfen, Osman (* 1977), German legal scholar
- Isfordink, Johann Nepomuk (1776–1841), military doctor and director of the Josephs Academy in Vienna
- Isfort, Tim (* 1967), German musician, producer and arranger
- Isfried von Ratzeburg († 1204), Premonstratensian, Bishop of Ratzeburg
Isg
- Isgaard (* 1972), German singer
- Isgró, Salvatore (1930-2004), Italian clergyman, Roman Catholic Archbishop of Sassari
- Išgum-Addu , ruler of Mari
- Isgur, Nathan (1947-2001), Canadian physicist
Ish
- Ishag, Lissy (* 1979), German television presenter
- Ishaghpour, Youssef (* 1940), Iranian university professor, philosopher, film sociologist, film critic
- İshak Efendi , Ottoman military engineer and natural scientist
- Ishak Pasha (1444–1487), Ottoman statesman, governor, general and grand vizier
- Ishak, Mikael (* 1993), Swedish football player of Syrian origin
- Ishak, Yusof bin (1910–1970), Singaporean politician, President of Singapore
- Ishak-Boushaki, Mustapha (* 1967), Algerian theoretical physicist
- İshaki, Ayaz (1878–1954), pan-Islamic and pan- Turkish agitator and journalist
- Ishaki, Meir , Grand Rabbi in Constantinople (1762–1780)
- Ishaković, Isa-Beg († 1470), Ottoman-Bosnian general
- Isham, Christopher (* 1944), British physicist
- Isham, Mark (* 1951), American composer for film music
- Isham, Wayne (born 1958), American director
- Ishanavarman II († 928), King of Angkor
- Ishaq ibn Ali († 1147), ruler of the Almoravids
- Ishāq ibn Hunain († 910), translator from Greek into Arabic
- Ishaq ibn Muhammad ibn Ghaniya († 1184), Wālī of Mallorca
- Ishaq Khan, Ghulam (1915-2006), Pakistani politician and President (1988-1993)
- Ishaq, Jacques (* 1938), Iraqi Chaldean Catholic clergyman, Curia Bishop in the Patriarchate of Babylon
- Ishaq, Maryam Yahya Ibrahim (* 1987), Sudanese Roman Catholic Christian
- Ishaq, Sara , Yemeni film producer
- Ishaque, Christine (* 1972), German national basketball player
- Ishara, Babu Ram (1934–2012), Indian film director and screenwriter
- Ishema, Lorna (* 1989), Ugandan-German actress
- Isherwood, Benjamin F. (1822-1915) American railroad and shipbuilding engineer
- Isherwood, Christopher (1904–1986), British-American writer
- Isherwood, Joseph (1870-1937), British naval engineer
- Ishi († 1916), Indian, last survivor of the Yahi
- Išḫi-Addu , King of Qatna
- Ishiaku, Manasseh (* 1983), Nigerian-Belgian football player
- Ishiba, Shigeru (* 1957), Japanese politician
- Ishibashi, Michinori (* 1952), Japanese judoka
- Ishibashi, Naoki (* 1981), Japanese soccer player
- Ishibashi, Ningetsu (1865–1926), Japanese literary critic and writer
- Ishibashi, Noriko , Japanese soccer player
- Ishibashi, Tanzan (1884–1973), Japanese Prime Minister
- Ishibitsu, Yōsuke (born 1983), Japanese football player
- Ishibumi, Ichiei (* 1981), Japanese light novel writer
- Ishida, Akira (* 1967), Japanese voice actor (Seiyū)
- Ishida, Baigan (1685–1744) Japanese scholar, founder of Shingaku
- Ishida, Eiichirō (1903–1968), Japanese anthropologist
- Ishida, Hakyō (1913-1969), Japanese poet
- Ishida, Hideyuki (* 1982), Japanese soccer player
- Ishida, Hiroyuki (* 1979), Japanese soccer player
- Ishida, Jun'ichi (born 1954), Japanese actor and television performer
- Ishida, Junko , Japanese soccer player
- Ishida, Masako (* 1980), Japanese cross-country skier
- Ishida, Masato (* 1983), Japanese soccer player
- Ishida, Masatoshi (* 1952), Japanese politician
- Ishida, Masatoshi (* 1995), Japanese soccer player
- Ishida, Mitsunari (1560–1600), Japanese military leader and daimyo
- Ishida, Nicole (* 1990), Japanese actress and model
- Ishida, Ryōma (* 1996), Japanese football player
- Ishida, Tanrō (* 1987), Japanese actor
- Ishida, Yōko (* 1973), Japanese singer
- Ishida, Yūki (born 1980), Japanese soccer player
- Ishidate, Yasuki (* 1984), Japanese soccer player
- Ishidō, Kazuto (* 1982), Japanese football player
- Ishidō, Keita (* 1992), Japanese football player
- Ishiepai, Benson (* 1936), Ugandan hurdler
- Ishigaki, Eitarō (1893–1958), Japanese painter
- Ishigaki, Rin (1920-2004), Japanese poet
- Ishigaki, Sumiko (* 1985), Japanese cross-country skier
- Ishigaki, Yuka (* 1989), Japanese table tennis player
- Ishigame, Akira (born 1985), Japanese soccer player
- Ishigami, Jun'ya (* 1974), Japanese architect
- Ishigami, Kōsei (* 1990), Japanese football player
- Ishigami, Naoya (born 1985), Japanese soccer player
- Ishigami, Peter Baptist Tadamarō (1920–2014), Japanese clergyman, Roman Catholic bishop of Naha
- Ishigami, Shōma (* 2002), Japanese football player
- Ishigami, Yoshinori (born 1957), Japanese soccer player
- Ishigamori, Sōma (* 2001), Japanese football player
- Ishige, Hideki (* 1994), Japanese soccer player
- Ishiguro, Hiroshi (* 1963), Japanese robotics
- Ishiguro, Kazuo (* 1954), British writer of Japanese origin
- Ishiguro, Munemaro (1893–1968), Japanese potter
- Ishiguro, Tadaatsu (1884–1960), Japanese politician
- Ishiguro, Tomohisa (* 1981), Japanese football player
- Ishihara, Daisuke (born 1971), Japanese soccer player
- Ishihara, Hirokazu (* 1999), Japanese soccer player
- Ishihara, Hirotaka (* 1964), Japanese politician
- Ishihara, Jun (1881-1947) Japanese physicist
- Ishihara, Katsuya (* 1978), Japanese soccer player
- Ishihara, Ken (1882–1976), Japanese historian
- Ishihara, Kenji (* 1934), Japanese geotechnical engineer
- Ishihara, Naoki (* 1984), Japanese soccer player
- Ishihara, Nobuteru (* 1957), Japanese politician
- Ishihara, Shinobu (1879–1963), Japanese ophthalmologist
- Ishihara, Shintarō (* 1932), Japanese writer and politician
- Ishihara, Tadaoki (* 1940), Japanese composer and professor
- Ishihara, Takayoshi (* 1992), Japanese soccer player
- Ishihara, Taku (* 1988), Japanese soccer player
- Ishihara, Tatsuya (* 1966), Japanese film director
- Ishihara, Toshimichi , Japanese badminton player
- Ishii, Baku (1886–1962), Japanese dancer and choreographer
- Ishii, Chiaki (* 1941), Brazilian judoka
- Ishii, Gakuryū (* 1957), Japanese film director
- Ishii, Hajime (born 1959), Japanese soccer player
- Ishii, Hakutei (1882–1958), Japanese painter and printmaker
- Ishii, Hidenori (* 1985), Japanese soccer player
- Ishii, Hiroo (* 1964), Japanese politician and baseball player
- Ishii, Hitoshi (* 1947), Japanese mathematician
- Ishii, Kaisei (* 2000), Japanese soccer player
- Ishii, Kan (1921–2009), Japanese composer
- Ishii, Keiichi (* 1958), Japanese politician
- Ishii, Keita (* 1995), Japanese soccer player
- Ishii, Ken (* 1970), Japanese techno DJ and producer
- Ishii, Kengo (* 1986), Japanese soccer player
- Ishii, Kenta (* 1987), Japanese soccer player
- Ishii, Kikujirō (1866-1945), Japanese diplomat and politician, Foreign Minister of Japan (1915-1916)
- Ishii, Kōki (1940-2002), Japanese politician
- Ishii, Kōki (* 1954), Japanese boxer
- Ishii, Kōki (born 1995), Japanese football player
- Ishii, Kuniko , Japanese actress
- Ishii, Maki (1936–2003), Japanese composer
- Ishii, Masahiro (* 1945), Japanese politician
- Ishii, Masatada (* 1967), Japanese soccer player
- Ishii, Midori (* 1949), Japanese politician
- Ishii, Motoko (* 1938), Japanese light artist
- Ishii, Ryō (* 1993), Japanese football player
- Ishii, Ryōsuke (1907-1993), Japanese legal historian
- Ishii, Satoshi (* 1986), Japanese judoka
- Ishii, Shigemi (* 1951), Japanese soccer player
- Ishii, Shigeo (1933–1962) Japanese painter
- Ishii, Shirō (1892-1959), Japanese medic
- Ishii, Sōjirō (* 1970), Japanese football player
- Ishii, Takakazu (* 1945), Japanese politician
- Ishii, Takashi (* 1946), Japanese director and screenwriter
- Ishii, Takashi (* 1954), Japanese middle-distance runner
- Ishii, Toshiya (* 1978), Japanese soccer player
- Ishii, Tsuruzō (1887–1973), Japanese painter
- Ishii, Yoshinobu (1939–2018), Japanese football player and coach
- Ishii, Yūsuke (* 1991), Japanese football player
- Ishikawa, Akira (1931–2015), Japanese lawyer and university professor
- Ishikawa, Akira (1934-2002), Japanese jazz musician
- Ishikawa, Chiaki (* 1969), Japanese singer and composer
- Ishikawa, Daichi (* 1996), Japanese soccer player
- Ishikawa, Emerick (1920-2006), American weightlifter
- Ishikawa, Goemon († 1594), Japanese robber
- Ishikawa, Haruna (* 1994), Japanese ski racer
- Ishikawa, Hironori (* 1988), Japanese soccer player
- Ishikawa, Hiroto (* 1998), Japanese soccer player
- Ishikawa, Jun (1899–1987), Japanese writer
- Ishikawa, Kaoru (1915–1989), Japanese chemist, developed the Ishikawa diagram
- Ishikawa, Kasumi (* 1993), Japanese table tennis player
- Ishikawa, Kei (* 1992), Japanese soccer player
- Ishikawa, Ken (1948-2006) Japanese manga artist
- Ishikawa, Ken (* 1970), Japanese soccer player
- Ishikawa, Kentarō (born 1970), Japanese football player
- Ishikawa, Kō (* 1970), Japanese football player
- Ishikawa, Masahiro (* 1990), Japanese soccer player
- Ishikawa, Miki (* 1991), American actress
- Ishikawa, Miyuki (* 1897), Japanese serial killer
- Ishikawa, Naohiro (* 1981), Japanese soccer player
- Ishikawa, Naoki (* 1985), Japanese soccer player
- Ishikawa, Naoto (* 1989), Japanese soccer player
- Ishikawa, Ryō (* 1991), Japanese golfer
- Ishikawa, Sanshirō (1876–1956), Japanese socialist and anarchist
- Ishikawa, Takuboku (1886–1912), Japanese poet and literary critic of the Meiji period
- Ishikawa, Tatsuya (* 1979), Japanese soccer player
- Ishikawa, Tatsuzō (1905–1985), Japanese writer
- Ishikawa, Tomohiro (* 1973), Japanese politician
- Ishikawa, Toraji (1875–1964) Japanese painter
- Ishikawa, Toshiki (* 1991), Japanese soccer player
- Ishikawa, Yoshinobu (* 1940), Japanese politician
- Ishikawa, Yui (* 1989), Japanese voice actress (Seiyū)
- Ishikawa, Yūji (* 1979), Japanese soccer player
- Ishikura, Saburō (born 1946), Japanese actor
- Ishimaru, Kiyotaka (* 1973), Japanese football player
- Ishimatsu, Guts (* 1949), Japanese boxer
- Ishimatsu, Hajime , Japanese jazz musician
- Ishimatsu, Haley (* 1992), American water diver
- Ishimine, Satoko (* 1975), Japanese singer-songwriter
- Ishimoto, Shinroku (1854–1912), General of the Imperial Japanese Army and Japanese Army Minister
- Ishimoto, Takashi (1935–2009), Japanese swimmer
- Ishimoto, Takeharu (* 1970), Japanese composer and musician
- Ishimoto, Yasuhiro (1921–2012), American-Japanese photographer
- Ishimoto, Yukari (* 1962), Japanese conductor
- Ishimure, Michiko (1927-2018), Japanese author
- Ishino, Takkyu (* 1967), Japanese techno producer and DJ
- Ishinomori, Shōtarō (1938–1998), Japanese manga artist
- Ishio, Ryōga (* 2000), Japanese football player
- Ishioka, Bin (* 1984), Japanese ice hockey player
- Ishioka, Eiko (1938–2012), Japanese designer and costume designer
- Ishisaka, Genki (* 1993), Japanese soccer player
- Ishitani, Goichi (* 1979), Japanese soccer player
- Ishiuchi, Miyako (* 1947), Japanese photographer
- Ishiura, Hiroaki (* 1981), Japanese racing car driver
- Ishiura, Taiga (* 2001), Japanese soccer player
- Ishiwa, Masato (* 1996), Japanese soccer player
- Ishiwara, Kanji (1889–1949), General in the Imperial Japanese Army
- Ishiwata, Asahi (* 1996), Japanese soccer player
- Ishiwata, Sōtarō (1891–1950), Japanese politician and financial expert
- Ishiwatari, Akihiro (* 1958), Japanese jazz and rock musician (guitar)
- Ishiwatari, Daisuke (* 1973), Japanese video game developer, musician and illustrator
- Ishizaka, Danjulo (* 1979), German cellist and professor
- Ishizaka, Kimishige (1925-2018), Japanese immunologist
- Ishizaka, Teruko (1926-2019), Japanese immunologist
- Ishizaka, Yōjirō (1900–1986), Japanese writer
- Ishizaka, Yukiko (* 1968), Japanese beach volleyball player
- Ishizaki, Kotomi (* 1979), Japanese curler
- Ishizaki, Kōyō (1884–1947), Japanese painter
- Ishizaki, Nobuhiro (born 1958), Japanese football player
- Ishizaki, Stefan (* 1982), Swedish football player
- Ishizawa, Noriaki (* 1985), Japanese soccer player
- Ishizawa, Yukari (* 1988), Japanese athlete
- Ishizu, Daisuke (* 1990), Japanese soccer player
- Ishizu, Mitsue (* 1914), Japanese discus and javelin thrower
- Ishizu, Sachie (* 1992), Japanese tennis player
- Ishizue, Kachiru , Mangaka and illustrator
- Ishizue, Ryūji (born 1964), Japanese football player
- Ishizuka, Keiji (* 1974), Japanese soccer player
- Ishizuka, Tatsumaro (1764–1823), Japanese historian
- Ishizuka, Tomoji (1906–1986), Japanese haiku poet and writer
- Ishmael, Kemal (born 1991), American football player
- Ishtar (* 1968), Israeli singer
Isi
- Isi , Egyptian treasurer
- Isi , Gaufürst
- Isidore , Greek philosopher
- Isidore of Kiev († 1463), Roman Catholic bishop
- Isidore of Madrid († 1130), saint of the Roman Catholic Church
- Isidore von Milet (442-537), Greek architect, physicist and mathematician
- Isidore of Pelusium , ascetic, abbot, theologian
- Isidore of Seville († 636), Bishop of Hispale; Author of Latin etymologiae and exegetical texts
- Isidor, Lazare (1813–1888), Grand Rabbi of France
- Isidoro, Micael (* 1982), Portuguese road cyclist
- Isidorus of Charax , Roman geographer
- Isidorus of Chios , saint, martyr and patron saint of Venice, of Chios and the sailors
- Isídrez, Julia (* 1967), Paraguayan ceramic artist
- Isidro, Pedro (* 1985), Portuguese athlete
- Isijara, Jesús (* 1989), Mexican soccer player
- Isik, Aydin (* 1978), cabaret artist, actor, director, author
- Işık, Ayhan (1929–1979), Turkish actor
- Işık, Esen (* 1969), Turkish-Swiss director and screenwriter
- Işık, Fikri (* 1965), Turkish politician
- Işık, Hasan Esat (1916–1989), Turkish diplomat and politician
- Işık, Haydar (* 1937), Kurdish teacher, writer and translator
- Işık, Mehmet Can (* 1993), Turkish soccer player
- Işık, Timur (* 1980), German actor
- Işık, Volkan (* 1967), Turkish rally driver
- Işılar, Osman Nuri (* 1953), Turkish football coach
- Isimat-Mirin, Nicolas (* 1991), French football player
- Isinder, Melchior († 1588), German Protestant theologian
- Ising, Erika (1928–2019), German Germanist and linguist
- Ising, Ernst (1900–1998), German-American mathematician and physicist
- Ising, Georg Hilmar (1637–1708), Protestant theologian, historian and author
- Ising, Gustav (1883–1960), Swedish particle physicist and geophysicist
- Ising, Ignaz (1845–1919), German balneologist and spa doctor
- Ising, Jane (1902–2012), German-American economist
- Ising, Johannes (1902–1971), German politician (CDU)
- Ising, Julius von (1832–1898), Prussian lieutenant general and commandant of the Berlin armory
- Ising, Meinhard von (1790–1861), Prussian major general
- Ising, Rudolf (1903–1992), American animator, film producer and director
- Isingrim († 1180), abbot of Ottobeuren monastery
- Isiordia, Raúl (* 1952), Mexican soccer player
- Isis , concubine of the ancient Egyptian king (pharaoh) Thutmose II and mother of king Thutmose III.
- Isisnofret , wife of Pharaoh Ramses II.
- Isitan, Isaac , Canadian documentary film director
- Isitt, Kate , British actress
- Isizoh, Denis Chidi (* 1956), Nigerian Roman Catholic clergyman and auxiliary bishop in Onitsha
Isj
- Isjaslav I (1024-1078), Grand Duke of Kiev
- Isjaslav II. († 1154), Grand Duke of the Kievan Rus
- Isjaslav III. († 1162), Prince of Chernigov, Grand Prince of Kiev
Isk
- Iskallatu , Queen of the Arabs at the time of the Assyrian King Sennacherib
- Iskandar Muda (1590–1636), 12th Sultan of Aceh in Sumatra
- Iskandar, Aide (* 1975), Singaporean football player
- Iskandar, Alif (* 1999), Singaporean football player
- Iskandar, Fashah (* 1995), Singaporean football player
- Iskandar, Mahmud Al-Haj (1932-2010), eighth king of Malaysia
- Iskandar, Mohd Azlan (* 1982), Malaysian squash player
- Iskandar, Shady Ahdy (* 1993), Egyptian-American football player
- Iskandarjan, Mnazakan Frunsewitsch (* 1967), Soviet wrestler
- Iskandarova, Saida (* 1980), Uzbek swimmer
- Iskandarow, Akbarscho (* 1951), Tajik politician and president
- Iskandarowa, Diloro (* 1960), Tajik university professor
- Iskandarowa, Faroghat (* 1955), Tajik Iranist and lecturer in the Tajik language
- Iskander, Fasil Abdulowitsch (1929–2016), Abkhazian writer
- Iske, Horst (* 1928), German politician (SPD) and sports scientist
- Iskender, Hagop (1871-1949), Turkish photographer
- Iskender, Sabri (* 1947), Bulgarian human rights activist, dissident
- Iškibal , ruler of the first Meerland dynasty
- İskilipli Atıf Hoca (1875–1926), Turkish religious scholar and author
- Iskowskich, Wassili Alexejewitsch (1939–2009), Russian mathematician
- Iskraut, Hans-Jürgen (1931–2016), German composer
- Iskraut, Karl (1854–1942), German clergyman and politician, MdR
- Iskrenow, Georgi (* 1990), US-Bulgarian ice hockey player
Isl
- Isla, José Francisco de (1703–1781), Spanish writer and translator
- Isla, Mauricio (* 1988), Chilean football player
- Islacker, Frank (* 1963), German soccer player
- Islacker, Franz (1926–1970), German football player
- Islacker, Mandy (* 1988), German soccer player
- İslâm III. Giray (1604–1654), Khan of the Crimean Khanate
- Islam, Alhaj Mohammed Dabirul (* 1948), Bangladeshi politician of the Awami League
- İslam, Ayşenur (* 1958), Turkish politician of the Adalet ve Kalkınma Partisi
- Islam, Faisal (* 1977), British journalist
- Islam, Kazi Nazrul (1899–1976), Bengali poet
- Ïsläm, Qanat (* 1984), Chinese boxer
- Islam, Zaheerul (* 1956), Pakistani military, director of the Pakistani Inter-Services Intelligence (ISI)
- Islambouli, Sabat († 1941), Syrian doctor
- Islambuli, Chalid (1955–1982), Egyptian radical Islamist army officer
- Islamchan, Bauyrschan (* 1993), Kazakh football player
- Islami, Kastriot (* 1952), Albanian politician (PS)
- İslamoğlu, Cem (* 1980), Turkish soccer player
- İslamoğlu, Mustafa (* 1960), Turkish Islamic theologian and writer
- Islamov, Rauf (* 1978), Azerbaijani Kamantsch player
- Islamović, Alen (* 1957), Yugoslav or Bosnian musician and singer
- Islamow, Alexander Alexandrovich (* 1986), Russian ice hockey player
- Islamzade, Akif (* 1948), Azerbaijani singer
- Islandsmoen, Sigurd (1881–1964), Norwegian composer
- Islas Mendoza, Héctor (* 1967), Mexican soccer player and coach
- Islas, Alejandro (* 1992), Mexican water diver
- Islas, Idulio (* 1987), Mexican Taekwondoin
- Islas, Luis (* 1965), Argentine soccer player
- Islas, Ricardo , Uruguayan soccer player
- Ísleifur Gissurarson (1006-1080), first bishop of Iceland and Greenland
- Islek, Yasin (* 1988), German-Turkish actor and model
- Islenjew, Iwan Iwanowitsch (1738–1784), Russian astronomer, mathematician and university professor
- Isler Béguin, Marie Anne (* 1956), French politician, MEP
- Isler, Alan (1934-2010), British writer
- İşler, Cenk (* 1974), German-Turkish soccer player
- Isler, Emma (1816–1886), founding member of the College for Women
- İşler, Emrullah (* 1960), Turkish theologian and politician
- Isler, Gabriela (* 1988), Venezuelan beauty queen and Miss Universe 2013
- Isler, Gerhart (* 1949), Swiss publicist and politician
- Isler, Hans Peter (* 1941), Swiss classical archaeologist
- Isler, Heinz (1926–2009), Swiss civil engineer
- Isler, Heinz (* 1960), Swiss cyclist
- Isler, JJ (* 1963), American sailor
- Isler, Jacob (1758–1837), Swiss businessman and politician
- Isler, Jakob (1809–1862), Swiss politician
- Isler, Jedidah , American astrophysicist and university professor
- Isler, Johann Luzius (1810–1877), Bündner confectioner
- Isler, Manuel († 2011), Swiss literary scholar and journalist
- Isler, Meyer (1807–1888), German philologist and librarian
- Isler, Michael (* 1984), Swiss athlete (high jump)
- Isler, Morton L. (* 1929), American ornithologist
- Isler, Otto (1910–1992), Swiss chemist
- Isler, Peter (1847–1921), Swiss professional officer
- Isler, Peter Emil (1851–1936), Swiss politician
- Isler, Tuna (* 1989), German basketball coach
- Isler, Ursula (1923–2007), Swiss writer
- Isler-Christ, Lydia (* 1964), Swiss pharmacist and politician (LDP)
- Isler-Kerényi, Cornelia (* 1942), Swiss classical archaeologist
- Isler-Leiner, Vera (1931–2015), Swiss photographer
- Isles, Carlin (* 1989), American rugby seven player and American football player
- Isles, Nabaté , American jazz trumpeter, television presenter and film composer
- Isley, Troy (* 1998), American boxer
- İşleyen, Ali (* 1982), Turkish soccer player
- Isliker, Henri (1922–2007), Swiss immunologist
- Islip, Simon († 1366), Archbishop of Canterbury
Ism
- Išma-ia , Sumerian scholar, mathematician
- Ismael, Luís , Portuguese actor and film director
- Ismaël, Valérien (* 1975), French football player and coach
- Ismagambetov, January (* 1986), Kazakh chess player
- Ismagilow, Sinfer Rischatowitsch (* 1947), Russian chemist and university professor
- Ismaik, Hasan (* 1977), Jordanian businessman and investor
- Ismail al-Ajami († 1130), head of the Ismailis in Syria
- Ismail Bey († 1791), Emir of the Mamluks and regent of Egypt
- Ismail bin Omar Abdul Aziz (1911–1994), Bruneian Vice Mufti of Johor, Chief Kadi of Johor and Mufti Negara Brunei (State Mufti of Brunei)
- İsmail Hakki Bey († 1927), Ottoman composer and musician
- İsmail Hakkı Bursevî (1653–1725), Ottoman mystic, scholar (Koran exegete), musician and poet from the Jelveti order
- Ismail I (1279-1325), Emir of Granada
- Ismail I (1487–1524), Iranian Shah (Safavid dynasty), high cleric of Safawiyya
- Ismāʿīl ibn Jaʿfar , Imam of the Seventh Shiites or Ismailis
- Ismail Ibrahim, Mohamed (* 1997), Djiboutian long-distance runner
- Ismail II (1339-1360), Emir of Granada (1359-1360)
- Ismail II (1537–1577), second Shah of the Safavid dynasty
- Ismail III. († 1773), last Safavid Shah of Persia without real power
- Ismail Nasiruddin Shah († 1979), 15th Sultan of Terengganu and 4th Malaysian electoral king (1965–1970)
- Ismail Pascha (1830–1895), Wali (until 1867) and Khedive (from 1867) of Egypt (1863–1879)
- Ismail Sabri Yaakob (* 1960), Malaysian politician
- İsmail YK (* 1978), Turkish pop musician
- Ismail, Abd al-Fattah (1939–1986), Yemeni politician (Yemeni Socialist Party), President of South Yemen (1978–1980)
- Ismail, Afa (* 1993), Maldivian athlete
- Ismail, Ahmed (* 1975), Egyptian boxer
- Ismail, Atik (* 1957), Finnish football player
- Ismail, Dhurgham (* 1994), Iraqi soccer player
- Ismail, Fakhri (* 1991), Brunei athlete and soccer player
- Ismail, Hamid (* 1987), Qatari soccer player
- Ismail, Ismail Ahmed (* 1984), Sudanese middle-distance runner
- Ismail, Jaseel P. (* 1972), Indian badminton player
- Ismail, Maisa Fathuhulla (* 1999), Maldivian badminton player
- Ismāʿil, Muhammad (* 1946), Afghan politician
- Ismail, Muhammad Hafez (1918–1997), Egyptian military man and diplomat
- Ismail, Muhammad Hakimi (* 1991), Malaysian triple jumper
- Ismāʿīl, Muhammad ibn , son of Ismail ibn Jafar, the 7th Imam of the Ismailis (Seventh Shiites)
- Ismail, Muhammad Zulfiqar (* 2000), Malaysian sprinter
- Ismail, Samir , Kuwaiti-Palestinian doctor
- Ismail, Sherif (* 1955), Egyptian engineer and politician
- Ismail, Taufiq (* 1935), Indonesian writer
- Ismail, Wan Azizah Wan (* 1952), Malaysian politician
- Ismaila, Halimat (* 1984), Nigerian athlete
- Ismaili, Emin (* 1982), Kosovar football player
- Ismaili, Fisnik (* 1973), Kosovar Albanian designer and politician
- Ismaili, Florijana (1995–2019), Swiss football player
- Ismaili, Hysni (* 1963), North Macedonian physician and politician
- Ismaili, Shaban (* 1989), Macedonian football player
- Ismaili, Vait (* 1988), Austrian-Macedonian football player
- Ismaili, Valbona (* 2003), German volleyball player
- Ismailov, Anzur (* 1985), Uzbek football player
- Ismailow, Abdulchakim Issakowitsch (1916-2010), Soviet soldier who hoisted the victory flag on the Reichstag
- Ismailow, Enwer (* 1955), Ukrainian folk and jazz guitarist
- Izmailov, Korman (* 1972), Bulgarian politician
- Izmailov, Marat Nailewitsch (* 1982), Russian football player
- Ismailow, Nikolai Fyodorowitsch (1891–1971), Russian revolutionary
- Ismailow, Telman Mardanowitsch (* 1956), Russian entrepreneur
- Ismaily (* 1990), Brazilian soccer player
- Ismaily, Shahzad , American bassist and composer
- Ismair, Bettina (* 1962), German founder of the "Open House - Open Heart" initiative
- Ismajli, Adelina (* 1979), Kosovar pop singer and photo model
- Ismajli, Ardian (* 1996), Albanian-Kosovar soccer player
- Ismajli, Gentiana (* 1984), Kosovar pop singer
- Ismajli, Zanfina (* 1985), Kosovar pop singer
- Ismajlovic, Robert (* 1975), Swiss model and actor
- Ismatullayev, Akbar (* 1991), Uzbek football player
- Ismaun, Kamal , Malaysian diplomat
- Ismay, Hastings, 1st Baron Ismay (1887–1965), British politician, diplomat and general
- Ismay, J. Bruce (1862-1937), White Star Line director
- Ismay, Thomas (1837–1899), British shipowner
- Ismayil, Javid (* 1972), Azerbaijani economist, lawyer, doctor of philosophy in economics
- İsmayılov, Əjdər (* 1938), Azerbaijani philologist and politician
- İsmayılova, Olqa (* 1985), Azerbaijani track cyclist
- İsmayılova, Xədicə (* 1976), Azerbaijani journalist
- Ismayr, Rudolf (1908–1998), German weightlifter
- Ismayr, Wolfgang (* 1942), German political scientist, professor for German government systems at the TU Dresden
- Išme-Dagan , ruler of Mari
- Išme-Dagan († 1935 BC), King of Babylonia
- Išme-Dagan I , Assyrian king
- Išme-Dagan II , 58th Assyrian king
- Ismenos , Attic black-figure vase painter
- Ismer, Roland (* 1974), German tax lawyer
- Ismer, Rolf (1913–1984), German politician (CDU), MdL
- İsmihan Sultan († 1585), wife of the Ottoman Grand Vizier Sokollu Mehmed Pasha
- Ismit, Anaqi (* 2001), Singaporean soccer player
- Ísmodes, Damián (* 1989), Peruvian soccer player
- Ismuchambetov, Baqtyqoscha (* 1948), Kazakh politician
Isn
- Isna, Pansau Na , Guinea-Bissau resistance fighter of the PAIGC
- Isnard, Clément († 1612), French bishop
- Isnard, Clemente (1917–2011), Brazilian religious, Bishop of Nova Friburgo
- Isnard, Francis (1945-2010), French football player
- Isnard, Jean (1901–1976), French cameraman
- Isnard, Jean Esprit (1707–1781), French Dominican and organ builder
- Isnard, Maximin († 1825), politician in the French Revolution
- Isnard, Octave († 1626), French bishop
- Isnardi Parente, Margherita (1928–2008), Italian philosopher and university professor
- Isner, John (born 1985), American tennis player
Iso
- Iso of St. Gallen († 871), Benedictine, teacher and hagiographer
- Iso von Wölpe (1167–1231), Bishop of Verden
- Iso, Mitsuo (* 1966), Japanese anime director, screenwriter and animator
- Iso-Hollo, Volmari (1907–1969), Finnish athlete
- Isoaho, Olli (* 1956), Finnish football goalkeeper
- Isoard, Joachim-Jean-Xavier d ' , French Christian scholar, bishop and cardinal
- Isoard-Vauvenargue, Marc Léon Bruno Joseph Gustave d ' , French chess player
- Isobe, Takayuki (* 1959), Japanese sprinter
- Isoda, Kōichi (1931–1987), Japanese literary critic and scholar
- Isoda, Koryūsai , Japanese painter
- Isoda, Povilas (* 1988), Lithuanian politician
- Isoda, Yoshikazu (* 1965), Japanese football player
- Isoe, Taisei (* 1997), Japanese soccer player
- Isogai, Hiromitsu (* 1969), Japanese football player
- Isogai, Rensuke (1886–1967), General of the Imperial Japanese Army, Governor of Hong Kong
- Isoir, André (1935–2016), French organist
- Isokoski, Soile (* 1957), Finnish opera, song and concert singer (lyric soprano)
- Isocrates (436 BC – 338 BC), Attic orator
- Isol (* 1972), Argentine illustrator, children's book author and singer
- Isola, Albert (1898–1991), French obstacle runner
- Isola, Frank (1925-2004), American jazz drummer
- Isola, Horst (* 1939), German politician (SPD)
- Ísola, Luciano (* 1993), Uruguayan football player
- Isola, Peter (1929-2006), Gibraltar politician
- Isolani, Gertrud (1899–1988), German journalist, writer and translator
- Isolani, Johann Ludwig Hektor von (1586–1640), Imperial General of the Croatian Horsemen in the Thirty Years' War
- Isolée , German musician
- Isomäki, Risto (* 1961), Finnish writer, science editor and environmental activist
- Isometsä, Jari (* 1968), Finnish cross-country skier
- Isomura, Ryōta (* 1991), Japanese football player
- Isono, Nobuhisa (* 1974), Japanese football player
- Isop, Utta (* 1974), Austrian philosopher, gender researcher and activist
- Isopescu, Claudio (1894–1956), Romanian Romanist, Italianist, Romanist and Hispanist, who worked mainly in Italy
- Isopescul, Demeter (1839–1901), Austrian high school teacher, member of the Reichsrat
- Isopi, Antonio (1758–1833), Italian-German sculptor
- Isopp, Rosemarie (1927–2019), Austrian radio presenter on ORF
- Isoria, Swiad (* 1984), Georgian chess master
- Isorni, Jacques (1911–1995), French lawyer and politician, member of the National Assembly
- Isossimow, Alexander Vladimirovich (1939–1997), Soviet boxer
- Isotamm, Johnny B. (1939-2014), Estonian poet
- Isotow, Danila Sergejewitsch (* 1991), Russian swimmer
- Isotow, Eduard Konstantinowitsch (1936–2003), Russian actor
- Isotow, Sergei Petrovich (1917–1983), Russian aeronautical engineer
- Isotow, Vadim (* 1989), Kazakh road cyclist
- Isotowa, Kira Vladimirovna (1931–2013), Russian singer (soprano) and music teacher
- Isou, Isidore (1925-2007), French author
- Isouard, Nicolas (1775–1818), Maltese composer of French origin
- Isoufi, Shabir (* 1992), Dutch-Afghan soccer player
- Isović, Safet (1936–2007), Bosnian musician
- Isoyama, Hiroshi (* 1937), Japanese aikido teacher
- Isoyama, Kazushi (* 1975), Japanese soccer player
- Isozaki, Arata (* 1931), Japanese architect
- Isozaki, Keita (* 1980), Japanese soccer player
- Isozaki, Ken'ichirō (* 1965), Japanese writer
Isp
- Išpakai , king of the Scythians
- Ispanow, Ilijas (* 1976), Kazakh politician
- İspirli, Sabahattin (1958–2012), Turkish soccer player, soccer coach
- Išpuini , King of Urartu
Isr
- Isra al-Mudallal , Palestinian journalist
- Israel ben Eliezer († 1760), founder of Hasidism
- Israel ben Josef , founder of the Remuh Synagogue in Krakow-Kazimierz
- Israel Hopstein von Koschnitz (1733-1814), Hasidic tzaddik and preacher
- Israel Ibn al-Naqawa († 1391), Spanish Jewish scholar
- Israel of Axum , King of Axum
- Israel von Stolin (1868–1921), Hasidic rabbi and mystic
- Israel, Agathe (* 1949), German psychiatrist, psychoanalyst and author
- Israel, August (1836–1906), German educator and philanthropist
- Israel, Christoph (* 1964), German pianist, composer, arranger and producer
- Israel, Clara (1876–1942), German social worker and first female magistrate in Prussia
- Israel, Daniel (1859–1901), Austrian painter
- Israel, Frank Pieter (* 1946), Dutch radio astronomer
- Israel, Georg († 1588), Bishop of the Unity of the Bohemian Brethren
- Israel, Jacob (1621–1674), German anatomist and surgeon
- Israel, James (1848–1926), German urologist and surgeon
- Israel, Joachim (1920–2001), Swedish sociologist, social psychologist and critical social theorist
- Israel, John (1833–1898), Hamburg lawyer, Member of the Bundestag
- Israel, Jonathan (* 1946), British historian
- Israel, Jürgen (* 1944), German editor, publicist and author
- Israel, Märt (* 1983), Estonian athlete
- Israel, Martha , Sorbian member of the People's Chamber of the GDR
- Israel, Ottokar (1919–2004), German historian, archivist and genealogist
- Israel, Regine (* 1958), German soccer player
- Israël, Rinus (* 1942), Dutch football player and coach
- Israel, Robert (* 1963), American film composer and conductor
- Israel, Robert B. , American mathematical physicist and mathematician
- Israel, Rouven (* 1994), German actor
- Israel, Rudolf (1916–1985), German major general in the Ministry for State Security (MfS) of the GDR
- Israel, Samuel (1802–1870), German merchant and member of the citizenship
- Israel, Siegfried (1928–2016), German sports doctor, GDR team doctor
- Israël, Stéphane (* 1971), French civil servant and manager
- Israel, Steve (* 1958), American politician (Democratic Party)
- Israel, Ulf , German film producer
- Israel, Uwe (* 1963), German historian
- Israel, Víctor (1929–2009), Spanish actor
- Israel, Werner (* 1931), Canadian physicist
- Israel, Wilfrid (1899–1943), philanthropist and businessman
- Israel, Wilhelm James (1881–1959), German urologist and surgeon
- Israel, Yoron (* 1963), American jazz musician
- Israeli, Isaak ben Salomon , Jewish doctor and philosopher (Neoplatonist)
- Israeljan, Ruslan (* 1961), Armenian politician
- Israels, Chuck (* 1936), American jazz bassist
- Israëls, Isaac (1865–1934), Dutch painter
- Israëls, Jozef (1824–1911), Dutch painter
- Israelski, Michaelis (* 1874), German businessman
- Israelsson, Erik (* 1989), Swedish football player
- Israelsson, Karl-Erik (1929–2013), Swedish long jumper and hurdler
- Israelsson, Sven (1920–1989), Swedish Nordic combined skier
- Israhel von Halle († 1480), Jewish businessman, money dealer and pawnbroker
- Israhel, Harmen († 1558), German merchant
- Israilow, Achlidin (* 1994), Kyrgyz football player
- Israilow, Hassan (1910–1944), Chechen poet, journalist and guerrilla fighter
- Israilow, Umar (1981–2009), Chechen paramilitary and human rights activist
- Israjeljan, Martun (* 1938), Armenian composer
- Israjeljan, Rafajel (1908–1973), Armenian-Soviet architect
- Israng, Christoph (* 1971), German diplomat
- Israpilow, Nariman Magomedrassulowitsch (* 1988), Russian wrestler
Eat
- Issa, Abdullahi (1922–1988), Somali Prime Minister of the Italian Somaliland Trust Territory (1956–1960)
- Issa, Ahmed (1943–1983), Chadian athlete
- Issa, Albert (1943–1993), Nigerien writer and publisher
- Issa, Darrell (* 1953), American politician (Republican Party), entrepreneur
- Issa, Esther (* 1998), Nigerian high jumper
- Issa, Ibrahim († 1986), Nigerien writer, journalist and manager
- Issa, Ismail (* 1989), Bulgarian-Turkish soccer player
- Issa, Mohamed (* 1998), German actor
- Issa, Muhammad bin Abdul Karim (* 1965), Saudi Arabian politician
- Issa, Pierre (* 1975), South African football player
- Issaakjan, Matewos (* 1998), Russian racing car driver
- Issabekow, Asim (* 1960), Kyrgyz politician
- Issacharoff, Jeremy (* 1955), Israeli diplomat, Ambassador of the State of Israel to Germany
- Issaew, Chassan (* 1952), Bulgarian wrestler
- Issah, Abass (* 1998), Ghanaian soccer player
- Issah, Kamal (* 1992), Ghanaian soccer player
- Issahakjan, Avetik (1875–1957), Armenian author and activist
- Issaitschew, Vladimir Evgenyevich (* 1986), Russian track and road cyclist
- Issajenko, Angella (* 1958), Canadian sprinter
- Issajenko, Denys (* 1980), Ukrainian ice hockey player
- Issajenko, Serhij (* 1987), Ukrainian snooker player
- Issajew, Anatoly Konstantinowitsch (1932-2016), Soviet football player
- Issajew, Mansur Mustafajewitsch (* 1986), Russian judoka
- Issajew, Mladen (1907–1991), Bulgarian poet
- Issak, Friedrich (1915–1991), Estonian javelin thrower
- Issaka, Amadou (1924–2004), Nigerien politician
- Issaka, Awudu (* 1979), Ghanaian soccer player
- Issaka, Hamadou Djibo (* 1977), Nigerien rower
- Issakadze, Liana (* 1946), Georgian violinist
- Issakides, Barbara (1914–2011), Austrian pianist and resistance fighter
- Issakova, Svetlana (* 1993), Estonian figure skater
- Issakow, Iwan Stepanowitsch (1894–1967), Soviet naval admiral
- Issakow, Vladimir Vyacheslavovich (* 1970), Russian sports shooter
- Issakowa, Yevgenia Leonidovna (* 1978), Russian athlete
- Issakowa, Marija Grigoryevna (1920–2011), Soviet speed skater
- Issakovsky, Michail Wassiljewitsch (1900–1973), Russian poet
- Issambourg, Ludivine (* 1983), French flautist (jazz, hip-hop)
- Issangulow, Ildar Ildussowitsch (* 1992), Russian ice hockey player
- Issara Kachaiwong (* 1983), Thai snooker player
- Issachenko, Alexander (1911–1978), Austro-Russian Slavist
- Issachenko, Alexander (* 1986), Kazakh biathlete
- Issachenko, Boris Walentinowitsch (* 1958), Belarusian archer and sports official
- Issachenko, Evgeni (* 1988), Russian natural track tobogganist
- Issachenko, Natalja (* 1986), Kazakh biathlete
- Issaurel, Salvator (1871–1944), French opera singer (tenor) and music teacher
- Issawi, Charles (1916-2000), Egyptian economic historian
- Issawi, Samer (* 1979), Palestinian member of the Democratic Front group for the liberation of Palestine
- Issberner-Haldane, Ernst (1886–1966), German-Australian palm reader, yoga teacher and occultist
- Isse, Hirsi Magan (1935–2008), Somali academic, guerrilla leader in the Somali Salvation Democratic Front and father of Ayaan Hirsi Ali, a critic of Islam
- Issekeschew, Ässet (* 1971), Kazakh politician
- Issel, Arturo (1842–1922), Italian geologist, paleontologist, prehistorian, and malacologist
- Issel, Dan (born 1948), American basketball player
- Issel, Georg Wilhelm (1785–1870), German painter and Hessian councilor
- Issel, Heinrich (1854–1934), German costume painter
- Issel, Verena (* 1982), German object and installation artist
- Issel, Werner (1884–1974), German architect
- Isselbach, Franz Fortunat von (1663–1734), German baron and general field master
- Isselburg, Peter , German draftsman, engraver, printer and publisher
- Isselhard, Wolf (1930–1998), German physician
- Isselhorst, Arnold (1615–1695), German lawyer and council secretary of the Hanseatic city of Lübeck
- Isselhorst, Erich (1906–1948), German lawyer, police officer and SS leader
- Isselhorst, Gotthard Arnold (1682–1765), German lawyer and mayor of the Hanseatic city of Lübeck
- Isselhorst, Johann Arnold (1720–1785), lawyer and mayor of the Hanseatic city of Lübeck
- Isselmann, Ernst (1885–1916), German painter
- Issels, Josef (1907–1998), German doctor, alternative medicine cancer therapist
- Issen, Roland (* 1938), German trade unionist and politician (SPD), Member of the Bundestag
- Issendorff, Franz von (1851–1908), Prussian major general
- Issendorff, Thomas von (1846–1913), Prussian lieutenant general
- Isser Großrubatscher, Johanna von (1802–1880), Tyrolean draftsman and writer
- Isser, Andreas , Transylvanian lexicographer and language didactic, Romance philologist and Romanist
- Isser, Franz (* 1932), Austrian bobsledder
- Isser, Fritz , Austrian bobsleigh athlete
- Isser, Heinrich (1928–2004), Austrian luge and bobsleigh athlete
- Isser, Maria (1929–2011), Austrian luge athlete
- Isserlein, Israel (1390–1460), German rabbi
- Isserles, Moses († 1572), Polish rabbi
- Isserlin, Max (1879–1941), German neurologist
- Isserlis, Julius (1888–1968), Russian pianist and composer
- Isserlis, Steven (* 1958), English cellist
- İşsever, Vahdettin (* 1968), Turkish boxer
- Issig, Peter (* 1965), German jazz bassist and video artist
- Issigonis, Alec (1906–1988), British automobile designer
- Issinbajewa, Jelena Gadschijewna (* 1982), Russian pole vaulter and Olympic champion
- Issing, Otmar (* 1936), German economist
- Ißleb, Jürgen (1940–2012), German football goalkeeper
- Issleib, Kurt (1919–1994), German chemist
- Issleib, Walter (* 1923), German diplomat, ambassador of the GDR
- Issler, Emil (1872–1952), Alsatian botanist and teacher
- Issler, Gaudenz (1853–1942), Swiss entrepreneur and politician
- Issler, Helen (* 1946), Swiss editor-in-chief and moderator at DRS
- Issler, Lothar (* 1943), German mechanical engineer and university professor
- Ißmer, Fritz (1865–1930), German administrative lawyer in Silesia
- Issmer, Volker (* 1943), German teacher, historian and writer
- Issojewa, Sajram (* 1942), Soviet and Tajik actress
- Issolina, Indarti (* 1976), Indonesian badminton player
- Issoufou Alfaga, Abdoulrazak (* 1994), Nigerian Taekwondoin
- Issoufou, Mahamadou (* 1952), Nigerien politician
- Issová, Klára (* 1979), Czech film and theater actress
- Issoze-Ngondet, Emmanuel (1961–2020), Gabonese politician (PDG) and diplomat
Is
- Ista, Kevyn (* 1984), Belgian racing cyclist
- Istad, Jon (1937–2012), Norwegian biathlete
- Istad, Sverre (* 1965), Norwegian biathlete
- Istad-Kristiansen, Gro Marit (* 1978), Norwegian biathlete
- İstanbulluoğlu, Garbis (1927–1994), Turkish football player
- Istanmäki, Sisko (* 1927), Finnish writer
- Ištar-šumu-ereš , scribe, scholar
- Istaz, Karl (1924-2007), Belgian wrestler and wrestler
- Istel, Edgar (1880–1948), German composer and musicologist
- Istel, Richard (* 1999), German singer and songwriter
- İstemi, Mehmet Sıddık (* 1989), Turkish soccer player
- Istenič, Lilijana (* 1931), Yugoslavian and Slovenian biologist
- Istenič, Rudi (* 1971), Slovenian football player
- Isterewicz, Philipp (* 1992), German moderator
- Isterheil, Heinz (1914–1990), German actor and theater director
- Istler, Josef (1919–2000), Czech painter
- Istóczy, Győző (1842–1915), Hungarian MP and writer
- Ištóková, Katarína (* 1986), Slovak soccer player
- Istomin, Denis (* 1986), Uzbek tennis player
- Istomin, Eugene (1925-2003), American pianist
- Istomin, Sergei , Russian-French-Canadian cellist and gambist
- Istomin, Sergei (* 1986), Kazakh weightlifter
- Istomin, Vladimir Ivanovich (1809–1855), Russian naval officer
- Istomina, Avdotja Ilyinichna (1799–1848), Russian ballerina
- Istomina, Marija Alexejewna (* 1997), Russian cross-country skier
- Istomina, Natalija (* 1973), Lithuanian politician
- Istook, Ernest (* 1950), American politician
- Istrate, Gavril (1914–2014), Romanian Romanist and Romanist
- Istrate, Nicolae (* 1982), Romanian bobsleigh athlete
- Istrățescu, Andrei (* 1975), Romanian chess player
- Istrati, Alexandre (1915–1991), Romanian-French painter and exponent of the Informel
- Istrati, Panait (1884–1935), French-speaking writer of Romanian origin
- Istrefi, Era (* 1994), Kosovar pop singer
- Istrefi, Ferat (* 1991), Albanian tennis player
- Istrefi, Nora (* 1986), Kosovar pop singer
- Istria, Dora d ' (1828–1888), Romanian-Albanian writer
- Istrokles , Greek vase painter or potter
- Ištup-ilum , ruler of Mari
- Istúriz, Francisco Javier de (1790–1871), Spanish statesman
- István Báncsa († 1270), Archbishop of Esztergom and the first Hungarian cardinal of the Roman Church
- Ištvan, Miloslav (1928–1990), Czech composer and music teacher
- Ištvan, Radomír (* 1959), Czech composer and music teacher
- Istvanffy, Miklós (1538–1615), Hungarian historian
Isu
- Isu , ancient Egyptian king of the 8th Dynasty
- Isuja, Matthias Joseph (1929–2016), Tanzanian clergyman, Roman Catholic bishop of Dodoma
- Isungset, Terje (* 1964), Norwegian jazz percussionist
Isw
- Iswaran, S. (* 1962), Singaporean politician
- Izvolsky, Alexander Petrovich (1856–1919), Russian diplomat and Foreign Minister
Isy
- Isyanov, Ravil (born 1962), Russian actor
- Isyllos , Greek poet